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FLT3
| Description | Receptor-type tyrosine-protein kinase FLT3 |
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Gene and Protein Information
| Gene ID | 2322 |
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| Uniprot Accession IDs | A0AVG9 B7ZLT7 B7ZLT8 F5H0A0 Q13414 |
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| Ensembl ID | ENSP00000241453 |
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| Symbol | CD135 FLK2 STK1 FLK2 STK1 CD135 FLK-2 |
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| Family | Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. |
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| Sequence | MPALARDGGQLPLLVVFSAMIFGTITNQDLPVIKCVLINHKNNDSSVGKSSSYPMVSESPEDLGCALRPQSSGTVYEAAAVEVDVSASITLQVLVDAPGNISCLWVFKHSSLNCQPHFDLQNRGVVSMVILKMTETQAGEYLLFIQSEATNYTILFTVSIRNTLLYTLRRPYFRKMENQDALVCISESVPEPIVEWVLCDSQGESCKEESPAVVKKEEKVLHELFGTDIRCCARNELGRECTRLFTIDLNQTPQTTLPQLFLKVGEPLWIRCKAVHVNHGFGLTWELENKALEEGNYFEMSTYSTNRTMIRILFAFVSSVARNDTGYYTCSSSKHPSQSALVTIVEKGFINATNSSEDYEIDQYEEFCFSVRFKAYPQIRCTWTFSRKSFPCEQKGLDNGYSISKFCNHKHQPGEYIFHAENDDAQFTKMFTLNIRRKPQVLAEASASQASCFSDGYPLPSWTWKKCSDKSPNCTEEITEGVWNRKANRKVFGQWVSSSTLNMSEAIKGFLVKCCAYNSLGTSCETILLNSPGPFPFIQDNISFYATIGVCLLFIVVLTLLICHKYKKQFRYESQLQMVQVTGSSDNEYFYVDFREYEYDLKWEFPRENLEFGKVLGSGAFGKVMNATAYGISKTGVSIQVAVKMLKEKADSSEREALMSELKMMTQLGSHENIVNLLGACTLSGPIYLIFEYCCYGDLLNYLRSKREKFHRTWTEIFKEHNFSFYPTFQSHPNSSMPGSREVQIHPDSDQISGLHGNSFHSEDEIEYENQKRLEEEEDLNVLTFEDLLCFAYQVAKGMEFLEFKSCVHRDLAARNVLVTHGKVVKICDFGLARDIMSDSNYVVRGNARLPVKWMAPESLFEGIYTIKSDVWSYGILLWEIFSLGVNPYPGIPVDANFYKLIQNGFKMDQPFYATEEIYIIMQSCWAFDSRKRPSFPNLTSFLGCQLADAEEAMYQNVDGRVSECPHTYQNRRPFSREMDLGLLSPQAQVEDS Show more |
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Homologous gene and protein info.
| Species | Gene ID | Gene Symbol | Name | Tax ID | Other Gene ID | Sources |
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| Chimp | 452508 | FLT3 | fms related tyrosine kinase 3 | 9598 | VGNC:7288 | OMA, EggNOG |
| Macaque | 721712 | FLT3 | fms related tyrosine kinase 3 | 9544 | | Inparanoid, OMA, EggNOG |
| Mouse | 14255 | Flt3 | FMS-like tyrosine kinase 3 | 10090 | MGI:95559 | Inparanoid, OMA, EggNOG |
| Rat | 140635 | Flt3 | fms-related tyrosine kinase 3 | 10116 | RGD:61308 | Inparanoid, OMA |
| Dog | 486025 | FLT3 | fms related tyrosine kinase 3 | 9615 | VGNC:40908 | Inparanoid, OMA, EggNOG |
| Horse | 100061780 | FLT3 | fms related tyrosine kinase 3 | 9796 | VGNC:18068 | Inparanoid, OMA, EggNOG |
| Cow | 512700 | FLT3 | fms related tyrosine kinase 3 | 9913 | VGNC:29042 | Inparanoid, OMA, EggNOG |
| Pig | 100515445 | FLT3 | fms related tyrosine kinase 3 | 9823 | | Inparanoid, OMA, EggNOG |
| Opossum | 100025262 | FLT3 | fms related tyrosine kinase 3 | 13616 | | Inparanoid, OMA, EggNOG |
| Platypus | 100090467 | FLT3 | fms related tyrosine kinase 3 | 9258 | | Inparanoid, OMA, EggNOG |
| Anole lizard | 100557093 | flt3 | fms related tyrosine kinase 3 | 28377 | | Inparanoid, OMA, EggNOG |
| Xenopus | | FLT3 | fms related tyrosine kinase 3 [Source:HGNC Symbol;Acc:HGNC:3765] | 8364 | | OMA, EggNOG |
| Zebrafish | 566708 | flt3 | fms-related tyrosine kinase 3 | 7955 | ZDB-GENE-050114-4 | Inparanoid, OMA, EggNOG |
Associated Recombinant Proteins
| Name | Specification and purity | Expression system | Protein label | Activity | View Details |
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Associated Antibodies
| Name | Specifications | Species reactivity | species | Application | View Details |
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Associated Approved Drugs
Associated Active Ligands
Pathway
| Data Source | Name | Explore more targets | Explore in Source |
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