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FLT3

DescriptionReceptor-type tyrosine-protein kinase FLT3

Gene and Protein Information

Gene ID2322
Uniprot Accession IDs P36888 A0AVG9 B7ZLT7 B7ZLT8 F5H0A0 Q13414
Ensembl ID ENSP00000241453
Symbol CD135 FLK2 STK1 FLK2 STK1 CD135 FLK-2
FamilyBelongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.
Sequence
MPALARDGGQLPLLVVFSAMIFGTITNQDLPVIKCVLINHKNNDSSVGKSSSYPMVSESPEDLGCALRPQSSGTVYEAAAVEVDVSASITLQVLVDAPGNISCLWVFKHSSLNCQPHFDLQNRGVVSMVILKMTETQAGEYLLFIQSEATNYTILFTVSIRNTLLYTLRRPYFRKMENQDALVCISESVPEPIVEWVLCDSQGESCKEESPAVVKKEEKVLHELFGTDIRCCARNELGRECTRLFTIDLNQTPQTTLPQLFLKVGEPLWIRCKAVHVNHGFGLTWELENKALEEGNYFEMSTYSTNRTMIRILFAFVSSVARNDTGYYTCSSSKHPSQSALVTIVEKGFINATNSSEDYEIDQYEEFCFSVRFKAYPQIRCTWTFSRKSFPCEQKGLDNGYSISKFCNHKHQPGEYIFHAENDDAQFTKMFTLNIRRKPQVLAEASASQASCFSDGYPLPSWTWKKCSDKSPNCTEEITEGVWNRKANRKVFGQWVSSSTLNMSEAIKGFLVKCCAYNSLGTSCETILLNSPGPFPFIQDNISFYATIGVCLLFIVVLTLLICHKYKKQFRYESQLQMVQVTGSSDNEYFYVDFREYEYDLKWEFPRENLEFGKVLGSGAFGKVMNATAYGISKTGVSIQVAVKMLKEKADSSEREALMSELKMMTQLGSHENIVNLLGACTLSGPIYLIFEYCCYGDLLNYLRSKREKFHRTWTEIFKEHNFSFYPTFQSHPNSSMPGSREVQIHPDSDQISGLHGNSFHSEDEIEYENQKRLEEEEDLNVLTFEDLLCFAYQVAKGMEFLEFKSCVHRDLAARNVLVTHGKVVKICDFGLARDIMSDSNYVVRGNARLPVKWMAPESLFEGIYTIKSDVWSYGILLWEIFSLGVNPYPGIPVDANFYKLIQNGFKMDQPFYATEEIYIIMQSCWAFDSRKRPSFPNLTSFLGCQLADAEEAMYQNVDGRVSECPHTYQNRRPFSREMDLGLLSPQAQVEDS
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Homologous gene and protein info.
SpeciesGene IDGene SymbolNameTax IDOther Gene IDSources
Chimp452508FLT3fms related tyrosine kinase 39598VGNC:7288OMA, EggNOG
Macaque721712FLT3fms related tyrosine kinase 39544Inparanoid, OMA, EggNOG
Mouse14255Flt3FMS-like tyrosine kinase 310090MGI:95559Inparanoid, OMA, EggNOG
Rat140635Flt3fms-related tyrosine kinase 310116RGD:61308Inparanoid, OMA
Dog486025FLT3fms related tyrosine kinase 39615VGNC:40908Inparanoid, OMA, EggNOG
Horse100061780FLT3fms related tyrosine kinase 39796VGNC:18068Inparanoid, OMA, EggNOG
Cow512700FLT3fms related tyrosine kinase 39913VGNC:29042Inparanoid, OMA, EggNOG
Pig100515445FLT3fms related tyrosine kinase 39823Inparanoid, OMA, EggNOG
Opossum100025262FLT3fms related tyrosine kinase 313616Inparanoid, OMA, EggNOG
Platypus100090467FLT3fms related tyrosine kinase 39258Inparanoid, OMA, EggNOG
Anole lizard100557093flt3fms related tyrosine kinase 328377Inparanoid, OMA, EggNOG
XenopusFLT3fms related tyrosine kinase 3 [Source:HGNC Symbol;Acc:HGNC:3765]8364OMA, EggNOG
Zebrafish566708flt3fms-related tyrosine kinase 37955ZDB-GENE-050114-4Inparanoid, OMA, EggNOG

Protein Classes

DTO Classes
protein    /    Kinase    /    Protein kinase    /    TK group    /    PDGFR family    /    Receptor-type tyrosine-protein kinase flt3

Associated Recombinant Proteins

NameSpecification and purityExpression systemProtein labelAvailabilityView Details

Associated Antibodies

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NameSpecificationsSpecies reactivityApplicationAvailabilityView Details

Associated Approved Drugs

    Associated Active Ligands

      Associated Diseases

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      NameDirect Associated TargetsDisease TypeMondoid

      Bibliography

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