FURIN

DescriptionFurin

Gene and Protein Information

Gene ID5045
Uniprot Accession IDs Q14336 Q6LBS3 Q9UCZ5
Ensembl ID ENSP00000483552
Symbol FUR PACE PCSK3 FUR PACE SPC1 PCSK3
FamilyBelongs to the peptidase S8 family. Furin subfamily.
Sequence
MELRPWLLWVVAATGTLVLLAADAQGQKVFTNTWAVRIPGGPAVANSVARKHGFLNLGQIFGDYYHFWHRGVTKRSLSPHRPRHSRLQREPQVQWLEQQVAKRRTKRDVYQEPTDPKFPQQWYLSGVTQRDLNVKAAWAQGYTGHGIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMNDNRHGTRCAGEVAAVANNGVCGVGVAYNARIGGVRMLDGEVTDAVEARSLGLNPNHIHIYSASWGPEDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREHDSCNCDGYTNSIYTLSISSATQFGNVPWYSEACSSTLATTYSSGNQNEKQIVTTDLRQKCTESHTGTSASAPLAAGIIALTLEANKNLTWRDMQHLVVQTSKPAHLNANDWATNGVGRKVSHSYGYGLLDAGAMVALAQNWTTVAPQRKCIIDILTEPKDIGKRLEVRKTVTACLGEPNHITRLEHAQARLTLSYNRRGDLAIHLVSPMGTRSTLLAARPHDYSADGFNDWAFMTTHSWDEDPSGEWVLEIENTSEANNYGTLTKFTLVLYGTAPEGLPVPPESSGCKTLTSSQACVVCEEGFSLHQKSCVQHCPPGFAPQVLDTHYSTENDVETIRASVCAPCHASCATCQGPALTDCLSCPSHASLDPVEQTCSRQSQSSRESPPQQQPPRLPPEVEAGQRLRAGLLPSHLPEVVAGLSCAFIVLVFVTVFLVLQLRSGFSFRGVKVYTMDRGLISYKGLPPEAWQEECPSDSEEDEGRGERTAFIKDQSAL
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Homologous gene and protein info.
SpeciesGene IDGene SymbolNameTax IDOther Gene IDSources
Chimp453652FURINfurin, paired basic amino acid cleaving enzyme9598VGNC:7766OMA, EggNOG
Macaque715813FURINfurin, paired basic amino acid cleaving enzyme9544Inparanoid, OMA, EggNOG
Mouse18550Furinfurin (paired basic amino acid cleaving enzyme)10090MGI:97513Inparanoid, OMA, EggNOG
Rat54281Furinfurin (paired basic amino acid cleaving enzyme)10116RGD:3274Inparanoid, OMA, EggNOG
Dog488746FURINfurin, paired basic amino acid cleaving enzyme9615VGNC:41010Inparanoid, OMA
Horse100068931FURINfurin, paired basic amino acid cleaving enzyme9796VGNC:18155Inparanoid, OMA
Cow281374FURINfurin, paired basic amino acid cleaving enzyme9913VGNC:29146Inparanoid, OMA
Chicken395457FURINfurin, paired basic amino acid cleaving enzyme9031CGNC:49330Inparanoid, OMA
Anole lizard100551704furinfurin, paired basic amino acid cleaving enzyme28377Inparanoid, OMA
Xenopus100327238furinfurin, paired basic amino acid cleaving enzyme8364XB-GENE-999035Inparanoid, OMA
Zebrafish566557furinafurin (paired basic amino acid cleaving enzyme) a7955ZDB-GENE-040901-1Inparanoid, OMA

Protein Classes

PANTHER Classes
protein    /    serine protease    /    Furin
DTO Classes
protein    /    Enzyme    /    Protease    /    Serine protease    /    Furin

Associated Recombinant Proteins

NameSpecification and purityExpression systemProtein labelActivityView Details

Associated Antibodies

NameSpecificationsSpecies reactivityspeciesApplicationView Details

Associated Approved Drugs

    Associated Active Ligands

      Associated Diseases

      NameDisease TypeMondoid

      Pathway

      Data SourceNameExplore more targetsExplore in Source