PIKFYVE

Description1-phosphatidylinositol 3-phosphate 5-kinase

Gene and Protein Information

Gene ID200576
Uniprot Accession IDs Q08AR7 Q08AR8 Q53ST3 Q53T36 Q8N5H0 Q8NB67 Phosphatidylinositol 3-phosphate 5-kinase
Ensembl ID ENSP00000264380
Symbol KIAA0981 PIP5K3 CFD FAB1 HEL37 PIP5K PIP5K3 ZFYVE29
Sequence
MATDDKTSPTLDSANDLPRSPTSPSHLTHFKPLTPDQDEPPFKSAYSSFVNLFRFNKERAEGGQGEQQPLSGSWTSPQLPSRTQSVRSPTPYKKQLNEELQRRSSALDTRRKAEPTFGGHDPRTAVQLRSLSTVLKRLKEIMEGKSQDSDLKQYWMPDSQCKECYDCSEKFTTFRRRHHCRLCGQIFCSRCCNQEIPGKFMGYTGDLRACTYCRKIALSYAHSTDSNSIGEDLNALSDSACSVSVLDPSEPRTPVGSRKASRNIFLEDDLAWQSLIHPDSSNTPLSTRLVSVQEDAGKSPARNRSASITNLSLDRSGSPMVPSYETSVSPQANRTYVRTETTEDERKILLDSVQLKDLWKKICHHSSGMEFQDHRYWLRTHPNCIVGKELVNWLIRNGHIATRAQAIAIGQAMVDGRWLDCVSHHDQLFRDEYALYRPLQSTEFSETPSPDSDSVNSVEGHSEPSWFKDIKFDDSDTEQIAEEGDDNLANSASPSKRTSVSSFQSTVDSDSAASISLNVELDNVNFHIKKPSKYPHVPPHPADQKEYLISDTGGQQLSISDAFIKESLFNRRVEEKSKELPFTPLGWHHNNLELLREENGEKQAMERLLSANHNHMMALLQQLLHSDSLSSSWRDIIVSLVCQVVQTVRPDVKNQDDDMDIRQFVHIKKIPGGKKFDSVVVNGFVCTKNIAHKKMSSCIKNPKILLLKCSIEYLYREETKFTCIDPIVLQEREFLKNYVQRIVDVRPTLVLVEKTVSRIAQDMLLEHGITLVINVKSQVLERISRMTQGDLVMSMDQLLTKPHLGTCHKFYMQIFQLPNEQTKTLMFFEGCPQHLGCTIKLRGGSDYELARVKEILIFMICVAYHSQLEISFLMDEFAMPPTLMQNPSFHSLIEGRGHEGAVQEQYGGGSIPWDPDIPPESLPCDDSSLLELRIVFEKGEQENKNLPQAVASVKHQEHSTTACPAGLPCAFFAPVPESLLPLPVDDQQDALGSEQPETLQQTVVLQDPKSQIRAFRDPLQDDTGLYVTEEVTSSEDKRKTYSLAFKQELKDVILCISPVITFREPFLLTEKGMRCSTRDYFAEQVYWSPLLNKEFKEMENRRKKQLLRDLSGLQGMNGSIQAKSIQVLPSHELVSTRIAEHLGDSQSLGRMLADYRARGGRIQPKNSDPFAHSKDASSTSSGQSGSKNEGDEERGLILSDAVWSTKVDCLNPINHQRLCVLFSSSSAQSSNAPSACVSPWIVTMEFYGKNDLTLGIFLERYCFRPSYQCPSMFCDTPMVHHIRRFVHGQGCVQIILKELDSPVPGYQHTILTYSWCRICKQVTPVVALSNESWSMSFAKYLELRFYGHQYTRRANAEPCGHSIHHDYHQYFSYNQMVASFSYSPIRLLEVCVPLPKIFIKRQAPLKVSLLQDLKDFFQKVSQVYVAIDERLASLKTDTFSKTREEKMEDIFAQKEMEEGEFKNWIEKMQARLMSSSVDTPQQLQSVFESLIAKKQSLCEVLQAWNNRLQDLFQQEKGRKRPSVPPSPGRLRQGEESKISAMDASPRNISPGLQNGEKEDRFLTTLSSQSSTSSTHLQLPTPPEVMSEQSVGGPPELDTASSSEDVFDGHLLGSTDSQVKEKSTMKAIFANLLPGNSYNPIPFPFDPDKHYLMYEHERVPIAVCEKEPSSIIAFALSCKEYRNALEELSKATQWNSAEEGLPTNSTSDSRPKSSSPIRLPEMSGGQTNRTTETEPQPTKKASGMLSFFRGTAGKSPDLSSQKRETLRGADSAYYQVGQTGKEGTENQGVEPQDEVDGGDTQKKQLINPHVELQFSDANAKFYCRLYYAGEFHKMREVILDSSEEDFIRSLSHSSPWQARGGKSGAAFYATEDDRFILKQMPRLEVQSFLDFAPHYFNYITNAVQQKRPTALAKILGVYRIGYKNSQNNTEKKLDLLVMENLFYGRKMAQVFDLKGSLRNRNVKTDTGKESCDVVLLDENLLKMVRDNPLYIRSHSKAVLRTSIHSDSHFLSSHLIIDYSLLVGRDDTSNELVVGIIDYIRTFTWDKKLEMVVKSTGILGGQGKMPTVVSPELYRTRFCEAMDKYFLMVPDHWTGLGLNC
Show more
Homologous gene and protein info.
SpeciesGene IDGene SymbolNameTax IDOther Gene IDSources
Chimp459908PIKFYVEphosphoinositide kinase, FYVE-type zinc finger containing9598VGNC:2754OMA, EggNOG
Macaque710115PIKFYVEphosphoinositide kinase, FYVE-type zinc finger containing9544Inparanoid, OMA, EggNOG
Mouse18711Pikfyvephosphoinositide kinase, FYVE type zinc finger containing10090MGI:1335106Inparanoid, OMA, EggNOG
Rat316457Pikfyvephosphoinositide kinase, FYVE-type zinc finger containing10116RGD:1592067Inparanoid, OMA, EggNOG
Dog478890PIKFYVEphosphoinositide kinase, FYVE-type zinc finger containing9615VGNC:44564Inparanoid, OMA, EggNOG
Horse100066445PIKFYVEphosphoinositide kinase, FYVE-type zinc finger containing9796VGNC:21455Inparanoid, OMA, EggNOG
Cow790873PIKFYVEphosphoinositide kinase, FYVE-type zinc finger containing9913VGNC:32898Inparanoid, OMA, EggNOG
Pig100521692PIKFYVEphosphoinositide kinase, FYVE-type zinc finger containing9823Inparanoid, OMA, EggNOG
Opossum100013564PIKFYVEphosphoinositide kinase, FYVE-type zinc finger containing13616Inparanoid, OMA, EggNOG
Platypus100076756PIKFYVEphosphoinositide kinase, FYVE-type zinc finger containing9258Inparanoid, EggNOG
Chicken424114PIKFYVEphosphoinositide kinase, FYVE-type zinc finger containing9031CGNC:6712Inparanoid, OMA, EggNOG
Anole lizard100566486pikfyvephosphoinositide kinase, FYVE-type zinc finger containing28377Inparanoid, OMA, EggNOG
Zebrafish337690pikfyvephosphoinositide kinase, FYVE finger containing7955ZDB-GENE-030131-9636Inparanoid, OMA, EggNOG
C. elegans181428ppk-3PIP Kinase6239Inparanoid, OMA, EggNOG
Fruitfly37033fab1fab1 kinase7227FBgn0028741Inparanoid, EggNOG
S.cerevisiae850574FAB11-phosphatidylinositol-3-phosphate 5-kinase4932S000001915Inparanoid, OMA, EggNOG

Protein Classes

DTO Classes
protein    /    Kinase    /    Non-protein kinase    /    Lipid kinase    /    1-phosphatidylinositol 3-phosphate 5-kinase

Associated Recombinant Proteins

NameSpecification and purityExpression systemProtein labelActivityView Details

Associated Antibodies

NameSpecificationsSpecies reactivityspeciesApplicationView Details

Associated Approved Drugs

    Associated Active Ligands

      Associated Diseases

      NameDisease TypeMondoid

      Pathway

      Data SourceNameExplore more targetsExplore in Source