FEN1
| Description | Flap endonuclease 1 |
|---|
Gene and Protein Information
| Gene ID | 2237 |
|---|---|
| Uniprot Accession IDs | FEN-1 |
| Ensembl ID | ENSP00000305480 |
| Symbol | RAD2 MF1 RAD2 FEN-1 |
| Family | Belongs to the XPG/RAD2 endonuclease family. FEN1 subfamily. |
| Sequence | MGIQGLAKLIADVAPSAIRENDIKSYFGRKVAIDASMSIYQFLIAVRQGGDVLQNEEGETTSHLMGMFYRTIRMMENGIKPVYVFDGKPPQLKSGELAKRSERRAEAEKQLQQAQAAGAEQEVEKFTKRLVKVTKQHNDECKHLLSLMGIPYLDAPSEAEASCAALVKAGKVYAAATEDMDCLTFGSPVLMRHLTASEAKKLPIQEFHLSRILQELGLNQEQFVDLCILLGSDYCESIRGIGPKRAVDLIQKHKSIEEIVRRLDPNKYPVPENWLHKEAHQLFLEPEVLDPESVELKWSEPNEEELIKFMCGEKQFSEERIRSGVKRLSKSRQGSTQGRLDDFFKVTGSLSSAKRKEPEPKGSTKKKAKTGAAGKFKRGK Show more |
Homologous gene and protein info.
| Species | Gene ID | Gene Symbol | Name | Tax ID | Other Gene ID | Sources |
|---|---|---|---|---|---|---|
| Chimp | 451242 | FEN1 | flap structure-specific endonuclease 1 | 9598 | VGNC:6752 | OMA, EggNOG |
| Macaque | 722348 | FEN1 | flap structure-specific endonuclease 1 | 9544 | Inparanoid, OMA, EggNOG | |
| Mouse | 14156 | Fen1 | flap structure specific endonuclease 1 | 10090 | MGI:102779 | Inparanoid, OMA, EggNOG |
| Rat | 84490 | Fen1 | flap structure-specific endonuclease 1 | 10116 | RGD:621821 | Inparanoid, OMA, EggNOG |
| Dog | 476063 | FEN1 | flap structure-specific endonuclease 1 | 9615 | VGNC:40817 | Inparanoid, OMA, EggNOG |
| Horse | 100059838 | FEN1 | flap structure-specific endonuclease 1 | 9796 | VGNC:17990 | Inparanoid, OMA, EggNOG |
| Cow | 616242 | FEN1 | flap structure-specific endonuclease 1 | 9913 | VGNC:28947 | Inparanoid, OMA, EggNOG |
| Pig | 100517749 | FEN1 | flap structure-specific endonuclease 1 | 9823 | Inparanoid, OMA, EggNOG | |
| Opossum | 100012289 | FEN1 | flap structure-specific endonuclease 1 | 13616 | Inparanoid, OMA, EggNOG | |
| Anole lizard | FEN1 | flap structure-specific endonuclease 1 [Source:HGNC Symbol;Acc:HGNC:3650] | 28377 | Inparanoid, OMA, EggNOG | ||
| Xenopus | 549759 | fen1 | flap structure-specific endonuclease 1 | 8364 | XB-GENE-955518 | Inparanoid, OMA, EggNOG |
| Zebrafish | 386707 | fen1 | flap structure-specific endonuclease 1 | 7955 | ZDB-GENE-031112-11 | Inparanoid, OMA, EggNOG |
| C. elegans | 171917 | crn-1 | Flap endonuclease 1 | 6239 | Inparanoid, OMA | |
| Fruitfly | 36887 | Fen1 | Flap endonuclease 1 | 7227 | FBgn0025832 | Inparanoid, OMA, EggNOG |
| S.cerevisiae | 853747 | RAD27 | multifunctional nuclease RAD27 | 4932 | S000001596 | Inparanoid, OMA, EggNOG |
Protein Classes
PANTHER Classes
protein / nucleic acid binding / damaged DNA-binding protein / Flap endonuclease 1
protein / nucleic acid binding / exodeoxyribonuclease / Flap endonuclease 1
protein / nucleic acid binding / nuclease / Flap endonuclease 1
protein / nucleic acid binding / endodeoxyribonuclease / Flap endonuclease 1
protein / nucleic acid binding / hydrolase / Flap endonuclease 1
protein / nucleic acid binding / damaged DNA-binding protein / Flap endonuclease 1
protein / nucleic acid binding / exodeoxyribonuclease / Flap endonuclease 1
protein / nucleic acid binding / nuclease / Flap endonuclease 1
protein / nucleic acid binding / endodeoxyribonuclease / Flap endonuclease 1
protein / nucleic acid binding / hydrolase / Flap endonuclease 1
Associated Recombinant Proteins
| Name | Specification and purity | Expression system | Protein label | Activity | View Details |
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Associated Antibodies
| Name | Specifications | Species reactivity | species | Application | View Details |
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Associated Approved Drugs
Associated Active Ligands
Associated Diseases
| Name | Disease Type | Mondoid |
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Pathway
| Data Source | Name | Explore more targets | Explore in Source |
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