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Protein or Target Summary

Flap endonuclease 1

Gene ID2237
uniprotP39748
Gene NameFEN1
Ensernbl IDENSP00000305480
FamilyBelongs to the XPG/RAD2 endonuclease family. FEN1 subfamily.
Sequence
MGIQGLAKLIADVAPSAIRENDIKSYFGRKVAIDASMSIYQFLIAVRQGGDVLQNEEGETTSHLMGMFYRTIRMMENGIKPVYVFDGKPPQLKSGELAKRSERRAEAEKQLQQAQAAGAEQEVEKFTKRLVKVTKQHNDECKHLLSLMGIPYLDAPSEAEASCAALVKAGKVYAAATEDMDCLTFGSPVLMRHLTASEAKKLPIQEFHLSRILQELGLNQEQFVDLCILLGSDYCESIRGIGPKRAVDLIQKHKSIEEIVRRLDPNKYPVPENWLHKEAHQLFLEPEVLDPESVELKWSEPNEEELIKFMCGEKQFSEERIRSGVKRLSKSRQGSTQGRLDDFFKVTGSLSSAKRKEPEPKGSTKKKAKTGAAGKFKRGK
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Gene and Protein Information

SpeciesGene IDGene SymbolGene NameUniprot
HUMAN2237FEN1Flap endonuclease 1P39748
MOUSEFen1Flap endonuclease 1Q3TGH6
MOUSEFen1Flap endonuclease 1Q99M86
MOUSEFen1Flap endonuclease 1Q8R069
MOUSE14156Fen1Flap endonuclease 1Q8C952
MOUSEFen1Flap endonuclease 1Q8C5X6
MOUSE14156Fen1Flap endonuclease 1Q91Z50
MOUSEFen1Flap endonuclease 1P39749
RAT84490Fen1Flap endonuclease 1Q5XIP6

Protein Classes

PANTHER Classes
protein    /    nucleic acid binding    /    damaged DNA-binding protein    /    Flap endonuclease 1
protein    /    nucleic acid binding    /    exodeoxyribonuclease    /    Flap endonuclease 1
protein    /    nucleic acid binding    /    nuclease    /    Flap endonuclease 1
protein    /    nucleic acid binding    /    endodeoxyribonuclease    /    Flap endonuclease 1
protein    /    nucleic acid binding    /    hydrolase    /    Flap endonuclease 1
DTO Classes
protein    /    Enzyme    /    Nuclease    /    Exodeoxyribonuclease    /    Flap endonuclease 1

Associated Recombinant Proteins

NameSpecification and purityExpression systemProtein labelActivityView Details

Associated Antibodies

NameSpecificationsSpecies reactivityspeciesApplicationView Details

Associated Approved Drugs

    Associated Active Ligands

      Associated Diseases

      NameDisease TypeMondoid

      Pathway

      Data SourceNameExplore more targetsExplore in Source