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PTK2B
| Description | Protein-tyrosine kinase 2-beta |
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Gene and Protein Information
| Gene ID | 2185 |
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| Uniprot Accession IDs | D3DST0 Q13475 Q14290 Q16709 Q6PID4 |
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| Ensembl ID | ENSP00000380638 |
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| Symbol | FAK2 PYK2 RAFTK PKB PTK CAKB FAK2 PYK2 CADTK FADK2 RAFTK |
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| Family | Belongs to the protein kinase superfamily. Tyr protein kinase family. FAK subfamily. |
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| Sequence | MSGVSEPLSRVKLGTLRRPEGPAEPMVVVPVDVEKEDVRILKVCFYSNSFNPGKNFKLVKCTVQTEIREIITSILLSGRIGPNIRLAECYGLRLKHMKSDEIHWLHPQMTVGEVQDKYECLHVEAEWRYDLQIRYLPEDFMESLKEDRTTLLYFYQQLRNDYMQRYASKVSEGMALQLGCLELRRFFKDMPHNALDKKSNFELLEKEVGLDLFFPKQMQENLKPKQFRKMIQQTFQQYASLREEECVMKFFNTLAGFANIDQETYRCELIQGWNITVDLVIGPKGIRQLTSQDAKPTCLAEFKQIRSIRCLPLEEGQAVLQLGIEGAPQALSIKTSSLAEAENMADLIDGYCRLQGEHQGSLIIHPRKDGEKRNSLPQIPMLNLEARRSHLSESCSIESDIYAEIPDETLRRPGGPQYGIAREDVVLNRILGEGFFGEVYEGVYTNHKGEKINVAVKTCKKDCTLDNKEKFMSEAVIMKNLDHPHIVKLIGIIEEEPTWIIMELYPYGELGHYLERNKNSLKVLTLVLYSLQICKAMAYLESINCVHRDIAVRNILVASPECVKLGDFGLSRYIEDEDYYKASVTRLPIKWMSPESINFRRFTTASDVWMFAVCMWEILSFGKQPFFWLENKDVIGVLEKGDRLPKPDLCPPVLYTLMTRCWDYDPSDRPRFTELVCSLSDVYQMEKDIAMEQERNARYRTPKILEPTAFQEPPPKPSRPKYRPPPQTNLLAPKLQFQVPEGLCASSPTLTSPMEYPSPVNSLHTPPLHRHNVFKRHSMREEDFIQPSSREEAQQLWEAEKVKMRQILDKQQKQMVEDYQWLRQEEKSLDPMVYMNDKSPLTPEKEVGYLEFTGPPQKPPRLGAQSIQPTANLDRTDDLVYLNVMELVRAVLELKNELCQLPPEGYVVVVKNVGLTLRKLIGSVDDLLPSLPSSSRTEIEGTQKLLNKDLAELINKMRLAQQNAVTSLSEECKRQMLTASHTLAVDAKNLLDAVDQAKVLANLAHPPAE Show more |
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Homologous gene and protein info.
| Species | Gene ID | Gene Symbol | Name | Tax ID | Other Gene ID | Sources |
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| Chimp | 464073 | PTK2B | protein tyrosine kinase 2 beta | 9598 | VGNC:811 | OMA, EggNOG |
| Macaque | 712787 | PTK2B | protein tyrosine kinase 2 beta | 9544 | | Inparanoid, OMA, EggNOG |
| Mouse | 19229 | Ptk2b | PTK2 protein tyrosine kinase 2 beta | 10090 | MGI:104908 | Inparanoid, OMA, EggNOG |
| Rat | 50646 | Ptk2b | protein tyrosine kinase 2 beta | 10116 | RGD:628758 | Inparanoid, OMA, EggNOG |
| Dog | 486102 | PTK2B | protein tyrosine kinase 2 beta | 9615 | VGNC:45159 | Inparanoid, OMA, EggNOG |
| Horse | 100054547 | PTK2B | protein tyrosine kinase 2 beta | 9796 | VGNC:22003 | Inparanoid, OMA, EggNOG |
| Cow | 541008 | PTK2B | protein tyrosine kinase 2 beta | 9913 | VGNC:33519 | Inparanoid, OMA, EggNOG |
| Pig | 100157507 | PTK2B | protein tyrosine kinase 2 beta | 9823 | | Inparanoid, OMA, EggNOG |
| Opossum | 100025175 | PTK2B | protein tyrosine kinase 2 beta | 13616 | | Inparanoid, EggNOG |
| Platypus | | PTK2B | protein tyrosine kinase 2 beta [Source:HGNC Symbol;Acc:HGNC:9612] | 9258 | | OMA, EggNOG |
| Chicken | 421998 | PTK2B | protein tyrosine kinase 2 beta | 9031 | CGNC:12407 | OMA, EggNOG |
| Anole lizard | | PTK2B | protein tyrosine kinase 2 beta [Source:HGNC Symbol;Acc:HGNC:9612] | 28377 | | Inparanoid, OMA |
| Xenopus | 496459 | ptk2b | protein tyrosine kinase 2 beta | 8364 | XB-GENE-489525 | Inparanoid, OMA, EggNOG |
| Zebrafish | 245950 | ptk2bb | protein tyrosine kinase 2 beta, b | 7955 | ZDB-GENE-020507-1 | Inparanoid, OMA, EggNOG |
| C. elegans | 172135 | kin-32 | Inactive tyrosine-protein kinase kin-32 | 6239 | | Inparanoid, EggNOG |
| Fruitfly | 37233 | Fak | Focal adhesion kinase | 7227 | FBgn0020440 | Inparanoid, EggNOG |
Associated Recombinant Proteins
| Name | Specification and purity | Expression system | Protein label | Activity | View Details |
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Associated Antibodies
| Name | Specifications | Species reactivity | species | Application | View Details |
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Associated Approved Drugs
Associated Active Ligands
Pathway
| Data Source | Name | Explore more targets | Explore in Source |
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