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FCGR3B

DescriptionLow affinity immunoglobulin gamma Fc region receptor III-B

Gene and Protein Information

Gene ID2215
Uniprot Accession IDs O75015
Ensembl ID ENSP00000433642
Symbol CD16B FCG3 FCGR3 IGFR3 CD16 FCG3 CD16A CD16b FCGR3 FCGR3A FCR-10 FCRIII FCRIIIb
Sequence
MWQLLLPTALLLLVSAGMRTEDLPKAVVFLEPQWYSVLEKDSVTLKCQGAYSPEDNSTQWFHNESLISSQASSYFIDAATVNDSGEYRCQTNLSTLSDPVQLEVHIGWLLLQAPRWVFKEEDPIHLRCHSWKNTALHKVTYLQNGKDRKYFHHNSDFHIPKATLKDSGSYFCRGLVGSKNVSSETVNITITQGLAVSTISSFSPPGYQVSFCLVMVLLFAVDTGLYFSVKTNI
Homologous gene and protein info.
SpeciesGene IDGene SymbolNameTax IDOther Gene IDSources
Cow281766FCGR3AFc fragment of IgG, low affinity IIIa, receptor (CD16a)9913Inparanoid, OMA

Protein Classes

PANTHER Classes
protein    /    cell adhesion molecule    /    Low affinity immunoglobulin gamma Fc region receptor III-B
DTO Classes
protein    /    Cell adhesion    /    Low affinity immunoglobulin gamma Fc region receptor III-B

Associated Antibodies

NameSpecificationsSpecies reactivityApplicationAvailabilityView Details

Associated Approved Drugs

    Associated Active Ligands

      Associated Diseases

      NameDirect Associated TargetsDisease TypeMondoid

      Bibliography

      1.Sondermann, P P, Huber, R R, Oosthuizen, V V and Jacob, U U. 2000-07-20 The 3.2-A crystal structure of the human IgG1 Fc fragment-Fc gammaRIII complex. [PMID:10917521]
      2.Zhang, Y Y and 6 more authors. 2000-09 Crystal structure of the extracellular domain of a human Fc gamma RIII. [PMID:11021536]
      3.Watanabe, Y Y and 7 more authors. 2000-09 Nucleotide sequence of a new Fc gamma receptor IIIB allele that codes for a neutrophil antigen. [PMID:11034564]
      4.Kuwano, S T ST and 7 more authors. 2000-11 Allelic polymorphisms of human fcgamma receptor IIa and Fcgamma receptor IIIb among distinct groups in Brazil. [PMID:11099670]
      5.Sugita, N N and 7 more authors. 2001-03 Increased frequency of FcgammaRIIIb-NA1 allele in periodontitis-resistant subjects in an elderly Japanese population. [PMID:11379895]
      6.Meisel, P P and 5 more authors. 2001-08 Polymorphisms of Fc gamma-receptors RIIa, RIIIa, and RIIIb in patients with adult periodontal diseases. [PMID:11528518]
      7.Kobayashi, T T and 7 more authors. 2001-10 The Fc gamma receptor genotype as a severity factor for chronic periodontitis in Japanese patients. [PMID:11699473]
      8.van der Pol, W L WL and 9 more authors. 2001-12-15 Relevance of Fcgamma receptor and interleukin-10 polymorphisms for meningococcal disease. [PMID:11740730]
      9.Taylor, James G JG and 5 more authors. 2002-02 Patterns of low-affinity immunoglobulin receptor polymorphisms in stroke and homozygous sickle cell disease. [PMID:11835346]
      10.Fu, Yali Y, Korostoff, Jonathan M JM, Fine, Daniel H DH and Wilson, Mark E ME. 2002-05 Fc gamma receptor genes as risk markers for localized aggressive periodontitis in African-Americans. [PMID:12027254]