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Protein or Target Summary

Cyclin-dependent kinase 7

Gene ID1022
uniprotP50613
Gene NameCDK7
Ensernbl IDENSP00000256443
FamilyBelongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.
Sequence
MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF
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Gene and Protein Information

SpeciesGene IDGene SymbolGene NameUniprot
HUMAN1022CDK7Cyclin-dependent kinase 7P50613
MOUSE12572Cdk7Cyclin-dependent kinase 7Q03147
MOUSECdk7Uncharacterized proteinQ3UJT4
MOUSECdk7Uncharacterized proteinQ8CAC4
MOUSECdk7Cyclin-dependent kinase 7A0A286YDC0
MOUSE12572Cdk7Cyclin-dependent kinase 7 (Homolog of Xenopus MO15 cdk-activating kinase)Q3THG5
RATCdk7Cyclin-dependent kinase 7P51952
RATCdk7Cyclin-dependent kinase 7F1LQC8

Protein Classes

PANTHER Classes
protein    /    non-receptor serine/threonine protein kinase    /    Cyclin-dependent kinase 7
protein    /    protein kinase    /    Cyclin-dependent kinase 7
protein    /    non-receptor tyrosine protein kinase    /    Cyclin-dependent kinase 7
protein    /    transferase    /    Cyclin-dependent kinase 7
protein    /    kinase    /    Cyclin-dependent kinase 7
DTO Classes
protein    /    Kinase    /    Protein kinase    /    CMGC group    /    CDK family    /    CDK7 subfamily    /    Cyclin-dependent kinase 7

Associated Recombinant Proteins

NameSpecification and purityExpression systemProtein labelActivityView Details

Associated Antibodies

NameSpecificationsSpecies reactivityspeciesApplicationView Details

Associated Approved Drugs

    Associated Active Ligands

      Associated Diseases

      NameDisease TypeMondoid

      Pathway

      Data SourceNameExplore more targetsExplore in Source