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Targets(Human)
MET

MET

Description	Hepatocyte growth factor receptor

Gene and Protein Information

Gene ID	4233
Uniprot Accession IDs	A1L467 B5A932 E7EQ94 O60366 Q12875 Q9UDX7 Q9UPL8 HGF receptor
Ensembl ID	ENSP00000317272
Symbol	HGFR AUTS9 RCCP2 c-Met DFNB97
Family	Belongs to the protein kinase superfamily. Tyr protein kinase family.
Sequence	MKAPAVLAPGILVLLFTLVQRSNGECKEALAKSEMNVNMKYQLPNFTAETPIQNVILHEHHIFLGATNYIYVLNEEDLQKVAEYKTGPVLEHPDCFPCQDCSSKANLSGGVWKDNINMALVVDTYYDDQLISCGSVNRGTCQRHVFPHNHTADIQSEVHCIFSPQIEEPSQCPDCVVSALGAKVLSSVKDRFINFFVGNTINSSYFPDHPLHSISVRRLKETKDGFMFLTDQSYIDVLPEFRDSYPIKYVHAFESNNFIYFLTVQRETLDAQTFHTRIIRFCSINSGLHSYMEMPLECILTEKRKKRSTKKEVFNILQAAYVSKPGAQLARQIGASLNDDILFGVFAQSKPDSAEPMDRSAMCAFPIKYVNDFFNKIVNKNNVRCLQHFYGPNHEHCFNRTLLRNSSGCEARRDEYRTEFTTALQRVDLFMGQFSEVLLTSISTFIKGDLTIANLGTSEGRFMQVVVSRSGPSTPHVNFLLDSHPVSPEVIVEHTLNQNGYTLVITGKKITKIPLNGLGCRHFQSCSQCLSAPPFVQCGWCHDKCVRSEECLSGTWTQQICLPAIYKVFPNSAPLEGGTRLTICGWDFGFRRNNKFDLKKTRVLLGNESCTLTLSESTMNTLKCTVGPAMNKHFNMSIIISNGHGTTQYSTFSYVDPVITSISPKYGPMAGGTLLTLTGNYLNSGNSRHISIGGKTCTLKSVSNSILECYTPAQTISTEFAVKLKIDLANRETSIFSYREDPIVYEIHPTKSFISGGSTITGVGKNLNSVSVPRMVINVHEAGRNFTVACQHRSNSEIICCTTPSLQQLNLQLPLKTKAFFMLDGILSKYFDLIYVHNPVFKPFEKPVMISMGNENVLEIKGNDIDPEAVKGEVLKVGNKSCENIHLHSEAVLCTVPNDLLKLNSELNIEWKQAISSTVLGKVIVQPDQNFTGLIAGVVSISTALLLLLGFFLWLKKRKQIKDLGSELVRYDARVHTPHLDRLVSARSVSPTTEMVSNESVDYRATFPEDQFPNSSQNGSCRQVQYPLTDMSPILTSGDSDISSPLLQNTVHIDLSALNPELVQAVQHVVIGPSSLIVHFNEVIGRGHFGCVYHGTLLDNDGKKIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHPNVLSLLGICLRSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKDLIGFGLQVAKGMKYLASKKFVHRDLAARNCMLDEKFTVKVADFGLARDMYDKEYYSVHNKTGAKLPVKWMALESLQTQKFTTKSDVWSFGVLLWELMTRGAPPYPDVNTFDITVYLLQGRRLLQPEYCPDPLYEVMLKCWHPKAEMRPSFSELVSRISAIFSTFIGEHYVHVNATYVNVKCVAPYPSLLSSEDNADDEVDTRPASFWETS Show more

Homologous gene and protein info.

Species	Gene ID	Gene Symbol	Name	Tax ID	Other Gene ID	Sources
Chimp	463671	MET	MET proto-oncogene, receptor tyrosine kinase	9598	VGNC:4426	Inparanoid, OMA, EggNOG
Macaque	704562	MET	MET proto-oncogene, receptor tyrosine kinase	9544		Inparanoid, OMA, EggNOG
Mouse	17295	Met	met proto-oncogene	10090	MGI:96969	Inparanoid, OMA, EggNOG
Rat	24553	Met	MET proto-oncogene, receptor tyrosine kinase	10116	RGD:3082	Inparanoid, OMA
Dog	403438	MET	MET proto-oncogene, receptor tyrosine kinase	9615	VGNC:43166	Inparanoid, OMA, EggNOG
Horse	100056013	MET	MET proto-oncogene, receptor tyrosine kinase	9796	VGNC:20111	Inparanoid, OMA, EggNOG
Cow	280855	MET	MET proto-oncogene, receptor tyrosine kinase	9913	VGNC:31394	Inparanoid, OMA, EggNOG
Opossum	100013788	MET	MET proto-oncogene, receptor tyrosine kinase	13616		Inparanoid, OMA, EggNOG
Platypus		MET	MET proto-oncogene, receptor tyrosine kinase [Source:HGNC Symbol;Acc:HGNC:7029]	9258		OMA, EggNOG
Anole lizard	100561443	met	MET proto-oncogene, receptor tyrosine kinase	28377		Inparanoid, OMA
Xenopus	100485823	met	MET proto-oncogene, receptor tyrosine kinase	8364	XB-GENE-481272	Inparanoid, OMA, EggNOG
Zebrafish	100150664	met	MET proto-oncogene, receptor tyrosine kinase	7955	ZDB-GENE-041014-1	Inparanoid, OMA, EggNOG

Protein Classes

DTO Classes
protein / Kinase / Protein kinase / TK group / MET family / Hepatocyte growth factor receptor

Associated Recombinant Proteins

Name	Specification and purity	Expression system	Protein label	Activity	View Details

Associated Antibodies

Name	Specifications	Species reactivity	species	Application	View Details

Associated Approved Drugs

Associated Active Ligands

Associated Diseases

Name	Disease Type	Mondoid

Pathway

Data Source	Name	Explore more targets	Explore in Source