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IGF1R

Description	Insulin-like growth factor 1 receptor

Gene and Protein Information

Gene ID	3480
Uniprot Accession IDs	B1B5Y2 Q14CV2 Q9UCC0
Ensembl ID	ENSP00000268035
Symbol	IGFR CD221 IGFIR JTK13
Family	Belongs to the protein kinase superfamily. Tyr protein kinase family. Insulin receptor subfamily.
Sequence	MKSGSGGGSPTSLWGLLFLSAALSLWPTSGEICGPGIDIRNDYQQLKRLENCTVIEGYLHILLISKAEDYRSYRFPKLTVITEYLLLFRVAGLESLGDLFPNLTVIRGWKLFYNYALVIFEMTNLKDIGLYNLRNITRGAIRIEKNADLCYLSTVDWSLILDAVSNNYIVGNKPPKECGDLCPGTMEEKPMCEKTTINNEYNYRCWTTNRCQKMCPSTCGKRACTENNECCHPECLGSCSAPDNDTACVACRHYYYAGVCVPACPPNTYRFEGWRCVDRDFCANILSAESSDSEGFVIHDGECMQECPSGFIRNGSQSMYCIPCEGPCPKVCEEEKKTKTIDSVTSAQMLQGCTIFKGNLLINIRRGNNIASELENFMGLIEVVTGYVKIRHSHALVSLSFLKNLRLILGEEQLEGNYSFYVLDNQNLQQLWDWDHRNLTIKAGKMYFAFNPKLCVSEIYRMEEVTGTKGRQSKGDINTRNNGERASCESDVLHFTSTTTSKNRIIITWHRYRPPDYRDLISFTVYYKEAPFKNVTEYDGQDACGSNSWNMVDVDLPPNKDVEPGILLHGLKPWTQYAVYVKAVTLTMVENDHIRGAKSEILYIRTNASVPSIPLDVLSASNSSSQLIVKWNPPSLPNGNLSYYIVRWQRQPQDGYLYRHNYCSKDKIPIRKYADGTIDIEEVTENPKTEVCGGEKGPCCACPKTEAEKQAEKEEAEYRKVFENFLHNSIFVPRPERKRRDVMQVANTTMSSRSRNTTAADTYNITDPEELETEYPFFESRVDNKERTVISNLRPFTLYRIDIHSCNHEAEKLGCSASNFVFARTMPAEGADDIPGPVTWEPRPENSIFLKWPEPENPNGLILMYEIKYGSQVEDQRECVSRQEYRKYGGAKLNRLNPGNYTARIQATSLSGNGSWTDPVFFYVQAKTGYENFIHLIIALPVAVLLIVGGLVIMLYVFHRKRNNSRLGNGVLYASVNPEYFSAADVYVPDEWEVAREKITMSRELGQGSFGMVYEGVAKGVVKDEPETRVAIKTVNEAASMRERIEFLNEASVMKEFNCHHVVRLLGVVSQGQPTLVIMELMTRGDLKSYLRSLRPEMENNPVLAPPSLSKMIQMAGEIADGMAYLNANKFVHRDLAARNCMVAEDFTVKIGDFGMTRDIYETDYYRKGGKGLLPVRWMSPESLKDGVFTTYSDVWSFGVVLWEIATLAEQPYQGLSNEQVLRFVMEGGLLDKPDNCPDMLFELMRMCWQYNPKMRPSFLEIISSIKEEMEPGFREVSFYYSEENKLPEPEELDLEPENMESVPLDPSASSSSLPLPDRHSGHKAENGPGPGVLVLRASFDERQPYAHMNGGRKNERALPLPQSSTC Show more

Homologous gene and protein info.

Species	Gene ID	Gene Symbol	Name	Tax ID	Other Gene ID	Sources
Chimp	453676	IGF1R	insulin like growth factor 1 receptor	9598	VGNC:11907	OMA, EggNOG
Macaque	708227	IGF1R	insulin like growth factor 1 receptor	9544		Inparanoid, OMA, EggNOG
Mouse	16001	Igf1r	insulin-like growth factor I receptor	10090	MGI:96433	Inparanoid, OMA, EggNOG
Rat	25718	Igf1r	insulin-like growth factor 1 receptor	10116	RGD:2869	Inparanoid, OMA, EggNOG
Dog	442951	IGF1R	insulin like growth factor 1 receptor	9615	VGNC:41896	Inparanoid, OMA
Horse	100055698	IGF1R	insulin like growth factor 1 receptor	9796	VGNC:18968	Inparanoid, OMA
Anole lizard	100554064	igf1r	insulin like growth factor 1 receptor	28377		Inparanoid, OMA
Xenopus	100329112	igf1r	insulin like growth factor 1 receptor	8364	XB-GENE-484032	Inparanoid, OMA
Zebrafish	245702	igf1rb	insulin-like growth factor 1b receptor	7955	ZDB-GENE-020503-2	Inparanoid, OMA

Protein Classes

DTO Classes
protein / Kinase / Protein kinase / TK group / INSR family / Insulin-like growth factor 1 receptor

Associated Recombinant Proteins

Name	Specification and purity	Expression system	Protein label	Activity	View Details

Associated Antibodies

Name	Specifications	Species reactivity	species	Application	View Details

Associated Approved Drugs

Associated Active Ligands

Associated Diseases

Name	Disease Type	Mondoid

Pathway

Data Source	Name	Explore more targets	Explore in Source

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