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IGF1R
Description | Insulin-like growth factor 1 receptor |
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Gene and Protein Information
Gene ID | 3480 |
Uniprot Accession IDs | B1B5Y2 Q14CV2 Q9UCC0 |
Ensembl ID | ENSP00000268035 |
Symbol | IGFR CD221 IGFIR JTK13 |
Family | Belongs to the protein kinase superfamily. Tyr protein kinase family. Insulin receptor subfamily. |
Sequence | MKSGSGGGSPTSLWGLLFLSAALSLWPTSGEICGPGIDIRNDYQQLKRLENCTVIEGYLHILLISKAEDYRSYRFPKLTVITEYLLLFRVAGLESLGDLFPNLTVIRGWKLFYNYALVIFEMTNLKDIGLYNLRNITRGAIRIEKNADLCYLSTVDWSLILDAVSNNYIVGNKPPKECGDLCPGTMEEKPMCEKTTINNEYNYRCWTTNRCQKMCPSTCGKRACTENNECCHPECLGSCSAPDNDTACVACRHYYYAGVCVPACPPNTYRFEGWRCVDRDFCANILSAESSDSEGFVIHDGECMQECPSGFIRNGSQSMYCIPCEGPCPKVCEEEKKTKTIDSVTSAQMLQGCTIFKGNLLINIRRGNNIASELENFMGLIEVVTGYVKIRHSHALVSLSFLKNLRLILGEEQLEGNYSFYVLDNQNLQQLWDWDHRNLTIKAGKMYFAFNPKLCVSEIYRMEEVTGTKGRQSKGDINTRNNGERASCESDVLHFTSTTTSKNRIIITWHRYRPPDYRDLISFTVYYKEAPFKNVTEYDGQDACGSNSWNMVDVDLPPNKDVEPGILLHGLKPWTQYAVYVKAVTLTMVENDHIRGAKSEILYIRTNASVPSIPLDVLSASNSSSQLIVKWNPPSLPNGNLSYYIVRWQRQPQDGYLYRHNYCSKDKIPIRKYADGTIDIEEVTENPKTEVCGGEKGPCCACPKTEAEKQAEKEEAEYRKVFENFLHNSIFVPRPERKRRDVMQVANTTMSSRSRNTTAADTYNITDPEELETEYPFFESRVDNKERTVISNLRPFTLYRIDIHSCNHEAEKLGCSASNFVFARTMPAEGADDIPGPVTWEPRPENSIFLKWPEPENPNGLILMYEIKYGSQVEDQRECVSRQEYRKYGGAKLNRLNPGNYTARIQATSLSGNGSWTDPVFFYVQAKTGYENFIHLIIALPVAVLLIVGGLVIMLYVFHRKRNNSRLGNGVLYASVNPEYFSAADVYVPDEWEVAREKITMSRELGQGSFGMVYEGVAKGVVKDEPETRVAIKTVNEAASMRERIEFLNEASVMKEFNCHHVVRLLGVVSQGQPTLVIMELMTRGDLKSYLRSLRPEMENNPVLAPPSLSKMIQMAGEIADGMAYLNANKFVHRDLAARNCMVAEDFTVKIGDFGMTRDIYETDYYRKGGKGLLPVRWMSPESLKDGVFTTYSDVWSFGVVLWEIATLAEQPYQGLSNEQVLRFVMEGGLLDKPDNCPDMLFELMRMCWQYNPKMRPSFLEIISSIKEEMEPGFREVSFYYSEENKLPEPEELDLEPENMESVPLDPSASSSSLPLPDRHSGHKAENGPGPGVLVLRASFDERQPYAHMNGGRKNERALPLPQSSTC Show more |
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Homologous gene and protein info.
Species | Gene ID | Gene Symbol | Name | Tax ID | Other Gene ID | Sources |
Chimp | 453676 | IGF1R | insulin like growth factor 1 receptor | 9598 | VGNC:11907 | OMA, EggNOG |
Macaque | 708227 | IGF1R | insulin like growth factor 1 receptor | 9544 | | Inparanoid, OMA, EggNOG |
Mouse | 16001 | Igf1r | insulin-like growth factor I receptor | 10090 | MGI:96433 | Inparanoid, OMA, EggNOG |
Rat | 25718 | Igf1r | insulin-like growth factor 1 receptor | 10116 | RGD:2869 | Inparanoid, OMA, EggNOG |
Dog | 442951 | IGF1R | insulin like growth factor 1 receptor | 9615 | VGNC:41896 | Inparanoid, OMA |
Horse | 100055698 | IGF1R | insulin like growth factor 1 receptor | 9796 | VGNC:18968 | Inparanoid, OMA |
Anole lizard | 100554064 | igf1r | insulin like growth factor 1 receptor | 28377 | | Inparanoid, OMA |
Xenopus | 100329112 | igf1r | insulin like growth factor 1 receptor | 8364 | XB-GENE-484032 | Inparanoid, OMA |
Zebrafish | 245702 | igf1rb | insulin-like growth factor 1b receptor | 7955 | ZDB-GENE-020503-2 | Inparanoid, OMA |
Associated Recombinant Proteins
Name | Specification and purity | Expression system | Protein label | Activity | View Details |
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Associated Antibodies
Name | Specifications | Species reactivity | species | Application | View Details |
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Associated Approved Drugs
Associated Active Ligands
Pathway
Data Source | Name | Explore more targets | Explore in Source |
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