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ITK
| Description | Tyrosine-protein kinase ITK/TSK |
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Gene and Protein Information
| Gene ID | 3702 |
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| Uniprot Accession IDs | B2R752 Q32ML7 |
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| Ensembl ID | ENSP00000398655 |
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| Symbol | EMT LYK EMT LYK LPFS1 PSCTK2 |
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| Family | Belongs to the protein kinase superfamily. Tyr protein kinase family. TEC subfamily. |
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| Sequence | MNNFILLEEQLIKKSQQKRRTSPSNFKVRFFVLTKASLAYFEDRHGKKRTLKGSIELSRIKCVEIVKSDISIPCHYKYPFQVVHDNYLLYVFAPDRESRQRWVLALKEETRNNNSLVPKYHPNFWMDGKWRCCSQLEKLATGCAQYDPTKNASKKPLPPTPEDNRRPLWEPEETVVIALYDYQTNDPQELALRRNEEYCLLDSSEIHWWRVQDRNGHEGYVPSSYLVEKSPNNLETYEWYNKSISRDKAEKLLLDTGKEGAFMVRDSRTAGTYTVSVFTKAVVSENNPCIKHYHIKETNDNPKRYYVAEKYVFDSIPLLINYHQHNGGGLVTRLRYPVCFGRQKAPVTAGLRYGKWVIDPSELTFVQEIGSGQFGLVHLGYWLNKDKVAIKTIREGAMSEEDFIEEAEVMMKLSHPKLVQLYGVCLEQAPICLVFEFMEHGCLSDYLRTQRGLFAAETLLGMCLDVCEGMAYLEEACVIHRDLAARNCLVGENQVIKVSDFGMTRFVLDDQYTSSTGTKFPVKWASPEVFSFSRYSSKSDVWSFGVLMWEVFSEGKIPYENRSNSEVVEDISTGFRLYKPRLASTHVYQIMNHCWKERPEDRPAFSRLLRQLAEIAESGL Show more |
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Homologous gene and protein info.
| Species | Gene ID | Gene Symbol | Name | Tax ID | Other Gene ID | Sources |
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| Chimp | 735556 | ITK | IL2 inducible T cell kinase | 9598 | VGNC:6939 | OMA, EggNOG |
| Macaque | 715471 | ITK | IL2 inducible T-cell kinase | 9544 | | Inparanoid, OMA, EggNOG |
| Mouse | 16428 | Itk | IL2 inducible T cell kinase | 10090 | MGI:96621 | Inparanoid, OMA, EggNOG |
| Rat | 363577 | Itk | IL2-inducible T-cell kinase | 10116 | RGD:1311618 | Inparanoid, OMA, EggNOG |
| Dog | 489159 | ITK | IL2 inducible T cell kinase | 9615 | VGNC:42149 | Inparanoid, OMA, EggNOG |
| Horse | 100071232 | ITK | IL2 inducible T cell kinase | 9796 | VGNC:19189 | Inparanoid, OMA, EggNOG |
| Cow | 522311 | ITK | IL2 inducible T cell kinase | 9913 | VGNC:30338 | Inparanoid, OMA, EggNOG |
| Opossum | 100030005 | ITK | IL2 inducible T-cell kinase | 13616 | | Inparanoid, EggNOG |
| Platypus | | ITK | IL2 inducible T cell kinase [Source:HGNC Symbol;Acc:HGNC:6171] | 9258 | | OMA, EggNOG |
| Chicken | 416247 | ITK | IL2 inducible T-cell kinase | 9031 | CGNC:2826 | Inparanoid, OMA |
| Anole lizard | 100554114 | itk | IL2 inducible T-cell kinase | 28377 | | Inparanoid, OMA |
| Zebrafish | 798906 | itk | IL2 inducible T cell kinase | 7955 | ZDB-GENE-990415-261 | Inparanoid, OMA |
Associated Recombinant Proteins
| Name | Specification and purity | Expression system | Protein label | Activity | View Details |
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Associated Antibodies
| Name | Specifications | Species reactivity | species | Application | View Details |
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Associated Approved Drugs
Associated Active Ligands
Pathway
| Data Source | Name | Explore more targets | Explore in Source |
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