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MERTK
| Description | Tyrosine-protein kinase Mer |
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Gene and Protein Information
| Gene ID | 10461 |
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| Uniprot Accession IDs | Q9HBB4 |
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| Ensembl ID | ENSP00000295408 |
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| Symbol | MER MER RP38 c-Eyk c-mer Tyro12 |
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| Family | Belongs to the protein kinase superfamily. Tyr protein kinase family. AXL/UFO subfamily. |
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| Sequence | MGPAPLPLLLGLFLPALWRRAITEAREEAKPYPLFPGPFPGSLQTDHTPLLSLPHASGYQPALMFSPTQPGRPHTGNVAIPQVTSVESKPLPPLAFKHTVGHIILSEHKGVKFNCSISVPNIYQDTTISWWKDGKELLGAHHAITQFYPDDEVTAIIASFSITSVQRSDNGSYICKMKINNEEIVSDPIYIEVQGLPHFTKQPESMNVTRNTAFNLTCQAVGPPEPVNIFWVQNSSRVNEQPEKSPSVLTVPGLTEMAVFSCEAHNDKGLTVSKGVQINIKAIPSPPTEVSIRNSTAHSILISWVPGFDGYSPFRNCSIQVKEADPLSNGSVMIFNTSALPHLYQIKQLQALANYSIGVSCMNEIGWSAVSPWILASTTEGAPSVAPLNVTVFLNESSDNVDIRWMKPPTKQQDGELVGYRISHVWQSAGISKELLEEVGQNGSRARISVQVHNATCTVRIAAVTRGGVGPFSDPVKIFIPAHGWVDYAPSSTPAPGNADPVLIIFGCFCGFILIGLILYISLAIRKRVQETKFGNAFTEEDSELVVNYIAKKSFCRRAIELTLHSLGVSEELQNKLEDVVIDRNLLILGKILGEGEFGSVMEGNLKQEDGTSLKVAVKTMKLDNSSQREIEEFLSEAACMKDFSHPNVIRLLGVCIEMSSQGIPKPMVILPFMKYGDLHTYLLYSRLETGPKHIPLQTLLKFMVDIALGMEYLSNRNFLHRDLAARNCMLRDDMTVCVADFGLSKKIYSGDYYRQGRIAKMPVKWIAIESLADRVYTSKSDVWAFGVTMWEIATRGMTPYPGVQNHEMYDYLLHGHRLKQPEDCLDELYEIMYSCWRTDPLDRPTFSVLRLQLEKLLESLPDVRNQADVIYVNTQLLESSEGLAQGSTLAPLDLNIDPDSIIASCTPRAAISVVTAEVHDSKPHEGRYILNGGSEEWEDLTSAPSAAVTAEKNSVLPGERLVRNGVSWSHSSMLPLGSSLPDELLFADDSSEGSEVLM Show more |
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Homologous gene and protein info.
| Species | Gene ID | Gene Symbol | Name | Tax ID | Other Gene ID | Sources |
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| Chimp | 459492 | MERTK | MER proto-oncogene, tyrosine kinase | 9598 | VGNC:485 | OMA, EggNOG |
| Macaque | 698330 | MERTK | MER proto-oncogene, tyrosine kinase | 9544 | | Inparanoid, OMA, EggNOG |
| Mouse | 17289 | Mertk | c-mer proto-oncogene tyrosine kinase | 10090 | MGI:96965 | Inparanoid, OMA, EggNOG |
| Rat | 65037 | Mertk | MER proto-oncogene, tyrosine kinase | 10116 | RGD:69283 | Inparanoid, OMA, EggNOG |
| Dog | 483060 | MERTK | MER proto-oncogene, tyrosine kinase | 9615 | VGNC:43162 | Inparanoid, OMA, EggNOG |
| Horse | 100064727 | MERTK | MER proto-oncogene, tyrosine kinase | 9796 | VGNC:20109 | Inparanoid, OMA, EggNOG |
| Cow | 504429 | MERTK | MER proto-oncogene, tyrosine kinase | 9913 | VGNC:31391 | Inparanoid, OMA, EggNOG |
| Opossum | 100033216 | MERTK | MER proto-oncogene, tyrosine kinase | 13616 | | Inparanoid, EggNOG |
| Chicken | 395836 | MERTK | MER proto-oncogene, tyrosine kinase | 9031 | CGNC:6255 | Inparanoid, OMA, EggNOG |
| Anole lizard | 100560737 | mertk | MER proto-oncogene, tyrosine kinase | 28377 | | Inparanoid, OMA, EggNOG |
| Xenopus | 100485743 | mertk | MER proto-oncogene, tyrosine kinase | 8364 | XB-GENE-493221 | Inparanoid, OMA, EggNOG |
| Zebrafish | 100322133 | mertka | c-mer proto-oncogene tyrosine kinase a | 7955 | ZDB-GENE-081107-1 | OMA, EggNOG |
Associated Recombinant Proteins
| Name | Specification and purity | Expression system | Protein label | Activity | View Details |
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Associated Antibodies
| Name | Specifications | Species reactivity | species | Application | View Details |
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Associated Approved Drugs
Associated Active Ligands
Pathway
| Data Source | Name | Explore more targets | Explore in Source |
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