| Description | Inositol 1,4,5-trisphosphate receptor type 1 |
|---|
Gene and Protein Information
| Gene ID | 3708 |
|---|---|
| Uniprot Accession IDs | E7EPX7 E9PDE9 Q14660 Q99897 |
| Ensembl ID | ENSP00000306253 |
| Symbol | INSP3R1 ACV CLA4 IP3R IP3R1 SCA15 SCA16 SCA29 INSP3R1 PPP1R94 |
| Family | Belongs to the InsP3 receptor family. |
| Sequence | MSDKMSSFLHIGDICSLYAEGSTNGFISTLGLVDDRCVVQPETGDLNNPPKKFRDCLFKLCPMNRYSAQKQFWKAAKPGANSTTDAVLLNKLHHAADLEKKQNETENRKLLGTVIQYGNVIQLLHLKSNKYLTVNKRLPALLEKNAMRVTLDEAGNEGSWFYIQPFYKLRSIGDSVVIGDKVVLNPVNAGQPLHASSHQLVDNPGCNEVNSVNCNTSWKIVLFMKWSDNKDDILKGGDVVRLFHAEQEKFLTCDEHRKKQHVFLRTTGRQSATSATSSKALWEVEVVQHDPCRGGAGYWNSLFRFKHLATGHYLAAEVDPDFEEECLEFQPSVDPDQDASRSRLRNAQEKMVYSLVSVPEGNDISSIFELDPTTLRGGDSLVPRNSYVRLRHLCTNTWVHSTNIPIDKEEEKPVMLKIGTSPVKEDKEAFAIVPVSPAEVRDLDFANDASKVLGSIAGKLEKGTITQNERRSVTKLLEDLVYFVTGGTNSGQDVLEVVFSKPNRERQKLMREQNILKQIFKLLQAPFTDCGDGPMLRLEELGDQRHAPFRHICRLCYRVLRHSQQDYRKNQEYIAKQFGFMQKQIGYDVLAEDTITALLHNNRKLLEKHITAAEIDTFVSLVRKNREPRFLDYLSDLCVSMNKSIPVTQELICKAVLNPTNADILIETKLVLSRFEFEGVSSTGENALEAGEDEEEVWLFWRDSNKEIRSKSVRELAQDAKEGQKEDRDVLSYYRYQLNLFARMCLDRQYLAINEISGQLDVDLILRCMSDENLPYDLRASFCRLMLHMHVDRDPQEQVTPVKYARLWSEIPSEIAIDDYDSSGASKDEIKERFAQTMEFVEEYLRDVVCQRFPFSDKEKNKLTFEVVNLARNLIYFGFYNFSDLLRLTKILLAILDCVHVTTIFPISKMAKGEENKGNNDVEKLKSSNVMRSIHGVGELMTQVVLRGGGFLPMTPMAAAPEGNVKQAEPEKEDIMVMDTKLKIIEILQFILNVRLDYRISCLLCIFKREFDESNSQTSETSSGNSSQEGPSNVPGALDFEHIEEQAEGIFGGSEENTPLDLDDHGGRTFLRVLLHLTMHDYPPLVSGALQLLFRHFSQRQEVLQAFKQVQLLVTSQDVDNYKQIKQDLDQLRSIVEKSELWVYKGQGPDETMDGASGENEHKKTEEGNNKPQKHESTSSYNYRVVKEILIRLSKLCVQESASVRKSRKQQQRLLRNMGAHAVVLELLQIPYEKAEDTKMQEIMRLAHEFLQNFCAGNQQNQALLHKHINLFLNPGILEAVTMQHIFMNNFQLCSEINERVVQHFVHCIETHGRNVQYIKFLQTIVKAEGKFIKKCQDMVMAELVNSGEDVLVFYNDRASFQTLIQMMRSERDRMDENSPLMYHIHLVELLAVCTEGKNVYTEIKCNSLLPLDDIVRVVTHEDCIPEVKIAYINFLNHCYVDTEVEMKEIYTSNHMWKLFENFLVDICRACNNTSDRKHADSILEKYVTEIVMSIVTTFFSSPFSDQSTTLQTRQPVFVQLLQGVFRVYHCNWLMPSQKASVESCIRVLSDVAKSRAIAIPVDLDSQVNNLFLKSHSIVQKTAMNWRLSARNAARRDSVLAASRDYRNIIERLQDIVSALEDRLRPLVQAELSVLVDVLHRPELLFPENTDARRKCESGGFICKLIKHTKQLLEENEEKLCIKVLQTLREMMTKDRGYGEKLISIDELDNAELPPAPDSENATEELEPSPPLRQLEDHKRGEALRQVLVNRYYGNVRPSGRRESLTSFGNGPLSAGGPGKPGGGGGGSGSSSMSRGEMSLAEVQCHLDKEGASNLVIDLIMNASSDRVFHESILLAIALLEGGNTTIQHSFFCRLTEDKKSEKFFKVFYDRMKVAQQEIKATVTVNTSDLGNKKKDDEVDRDAPSRKKAKEPTTQITEEVRDQLLEASAATRKAFTTFRREADPDDHYQPGEGTQATADKAKDDLEMSAVITIMQPILRFLQLLCENHNRDLQNFLRCQNNKTNYNLVCETLQFLDCICGSTTGGLGLLGLYINEKNVALINQTLESLTEYCQGPCHENQNCIATHESNGIDIITALILNDINPLGKKRMDLVLELKNNASKLLLAIMESRHDSENAERILYNMRPKELVEVIKKAYMQGEVEFEDGENGEDGAASPRNVGHNIYILAHQLARHNKELQSMLKPGGQVDGDEALEFYAKHTAQIEIVRLDRTMEQIVFPVPSICEFLTKESKLRIYYTTERDEQGSKINDFFLRSEDLFNEMNWQKKLRAQPVLYWCARNMSFWSSISFNLAVLMNLLVAFFYPFKGVRGGTLEPHWSGLLWTAMLISLAIVIALPKPHGIRALIASTILRLIFSVGLQPTLFLLGAFNVCNKIIFLMSFVGNCGTFTRGYRAMVLDVEFLYHLLYLVICAMGLFVHEFFYSLLLFDLVYREETLLNVIKSVTRNGRSIILTAVLALILVYLFSIVGYLFFKDDFILEVDRLPNETAVPETGESLASEFLFSDVCRVESGENCSSPAPREELVPAEETEQDKEHTCETLLMCIVTVLSHGLRSGGGVGDVLRKPSKEEPLFAARVIYDLLFFFMVIIIVLNLIFGVIIDTFADLRSEKQKKEEILKTTCFICGLERDKFDNKTVTFEEHIKEEHNMWHYLCFIVLVKVKDSTEYTGPESYVAEMIKERNLDWFPRMRAMSLVSSDSEGEQNELRNLQEKLESTMKLVTNLSGQLSELKDQMTEQRKQKQRIGLLGHPPHMNVNPQQPA Show more |
Homologous gene and protein info.
| Species | Gene ID | Gene Symbol | Name | Tax ID | Other Gene ID | Sources |
|---|---|---|---|---|---|---|
| Chimp | 460134 | ITPR1 | inositol 1,4,5-trisphosphate receptor type 1 | 9598 | VGNC:7976 | OMA, EggNOG |
| Macaque | 703669 | ITPR1 | inositol 1,4,5-trisphosphate receptor type 1 | 9544 | OMA, EggNOG | |
| Mouse | 16438 | Itpr1 | inositol 1,4,5-trisphosphate receptor 1 | 10090 | MGI:96623 | Inparanoid, OMA |
| Rat | 25262 | Itpr1 | inositol 1,4,5-trisphosphate receptor, type 1 | 10116 | RGD:2933 | Inparanoid, OMA |
| Dog | 476548 | ITPR1 | inositol 1,4,5-trisphosphate receptor type 1 | 9615 | VGNC:42157 | Inparanoid, OMA |
| Horse | 100052808 | ITPR1 | inositol 1,4,5-trisphosphate receptor type 1 | 9796 | VGNC:19194 | Inparanoid, OMA |
| Cow | 317697 | ITPR1 | inositol 1,4,5-trisphosphate receptor type 1 | 9913 | VGNC:30346 | Inparanoid, OMA |
| Opossum | 100013305 | ITPR1 | inositol 1,4,5-trisphosphate receptor type 1 | 13616 | Inparanoid, OMA | |
| Chicken | 395412 | ITPR1 | inositol 1,4,5-trisphosphate receptor type 1 | 9031 | CGNC:49305 | Inparanoid, OMA |
| Anole lizard | 100568038 | itpr1 | inositol 1,4,5-trisphosphate receptor type 1 | 28377 | Inparanoid, OMA | |
| Xenopus | 100493341 | itpr1 | inositol 1,4,5-trisphosphate receptor type 1 | 8364 | XB-GENE-920765 | Inparanoid, OMA |
Protein Classes
PANTHER Classes
protein / transporter / ion channel / Inositol 1,4,5-trisphosphate receptor type 1
protein / transporter / ligand-gated ion channel / Inositol 1,4,5-trisphosphate receptor type 1
protein / transporter / receptor / Inositol 1,4,5-trisphosphate receptor type 1
protein / transporter / ion channel / Inositol 1,4,5-trisphosphate receptor type 1
protein / transporter / ligand-gated ion channel / Inositol 1,4,5-trisphosphate receptor type 1
protein / transporter / receptor / Inositol 1,4,5-trisphosphate receptor type 1
DTO Classes
protein / Ion channel / Ryanodine-inositol 1,4,5-triphosphate receptor calcium channel (rir-cac) family / Inositol 1,4,5-trisphosphate receptor type 1
protein / Ion channel / Ryanodine-inositol 1,4,5-triphosphate receptor calcium channel (rir-cac) family / Inositol 1,4,5-trisphosphate receptor type 1
Associated Recombinant Proteins
| Name | Specification and purity | Expression system | Protein label | Activity | View Details |
|---|
Associated Antibodies
| Name | Specifications | Species reactivity | species | Application | View Details |
|---|
Associated Approved Drugs
Associated Active Ligands
Associated Diseases
| Name | Disease Type | Mondoid |
|---|
Pathway
| Data Source | Name | Explore more targets | Explore in Source |
|---|