Protein or Target Summary
Inositol 1,4,5-trisphosphate receptor type 1
| Gene ID | 3708 |
|---|---|
| uniprot | Q14643 |
| Gene Name | ITPR1 |
| Ensernbl ID | ENSP00000306253 |
| Family | Belongs to the InsP3 receptor family. |
| Sequence | MSDKMSSFLHIGDICSLYAEGSTNGFISTLGLVDDRCVVQPETGDLNNPPKKFRDCLFKLCPMNRYSAQKQFWKAAKPGANSTTDAVLLNKLHHAADLEKKQNETENRKLLGTVIQYGNVIQLLHLKSNKYLTVNKRLPALLEKNAMRVTLDEAGNEGSWFYIQPFYKLRSIGDSVVIGDKVVLNPVNAGQPLHASSHQLVDNPGCNEVNSVNCNTSWKIVLFMKWSDNKDDILKGGDVVRLFHAEQEKFLTCDEHRKKQHVFLRTTGRQSATSATSSKALWEVEVVQHDPCRGGAGYWNSLFRFKHLATGHYLAAEVDPDFEEECLEFQPSVDPDQDASRSRLRNAQEKMVYSLVSVPEGNDISSIFELDPTTLRGGDSLVPRNSYVRLRHLCTNTWVHSTNIPIDKEEEKPVMLKIGTSPVKEDKEAFAIVPVSPAEVRDLDFANDASKVLGSIAGKLEKGTITQNERRSVTKLLEDLVYFVTGGTNSGQDVLEVVFSKPNRERQKLMREQNILKQIFKLLQAPFTDCGDGPMLRLEELGDQRHAPFRHICRLCYRVLRHSQQDYRKNQEYIAKQFGFMQKQIGYDVLAEDTITALLHNNRKLLEKHITAAEIDTFVSLVRKNREPRFLDYLSDLCVSMNKSIPVTQELICKAVLNPTNADILIETKLVLSRFEFEGVSSTGENALEAGEDEEEVWLFWRDSNKEIRSKSVRELAQDAKEGQKEDRDVLSYYRYQLNLFARMCLDRQYLAINEISGQLDVDLILRCMSDENLPYDLRASFCRLMLHMHVDRDPQEQVTPVKYARLWSEIPSEIAIDDYDSSGASKDEIKERFAQTMEFVEEYLRDVVCQRFPFSDKEKNKLTFEVVNLARNLIYFGFYNFSDLLRLTKILLAILDCVHVTTIFPISKMAKGEENKGNNDVEKLKSSNVMRSIHGVGELMTQVVLRGGGFLPMTPMAAAPEGNVKQAEPEKEDIMVMDTKLKIIEILQFILNVRLDYRISCLLCIFKREFDESNSQTSETSSGNSSQEGPSNVPGALDFEHIEEQAEGIFGGSEENTPLDLDDHGGRTFLRVLLHLTMHDYPPLVSGALQLLFRHFSQRQEVLQAFKQVQLLVTSQDVDNYKQIKQDLDQLRSIVEKSELWVYKGQGPDETMDGASGENEHKKTEEGNNKPQKHESTSSYNYRVVKEILIRLSKLCVQESASVRKSRKQQQRLLRNMGAHAVVLELLQIPYEKAEDTKMQEIMRLAHEFLQNFCAGNQQNQALLHKHINLFLNPGILEAVTMQHIFMNNFQLCSEINERVVQHFVHCIETHGRNVQYIKFLQTIVKAEGKFIKKCQDMVMAELVNSGEDVLVFYNDRASFQTLIQMMRSERDRMDENSPLMYHIHLVELLAVCTEGKNVYTEIKCNSLLPLDDIVRVVTHEDCIPEVKIAYINFLNHCYVDTEVEMKEIYTSNHMWKLFENFLVDICRACNNTSDRKHADSILEKYVTEIVMSIVTTFFSSPFSDQSTTLQTRQPVFVQLLQGVFRVYHCNWLMPSQKASVESCIRVLSDVAKSRAIAIPVDLDSQVNNLFLKSHSIVQKTAMNWRLSARNAARRDSVLAASRDYRNIIERLQDIVSALEDRLRPLVQAELSVLVDVLHRPELLFPENTDARRKCESGGFICKLIKHTKQLLEENEEKLCIKVLQTLREMMTKDRGYGEKLISIDELDNAELPPAPDSENATEELEPSPPLRQLEDHKRGEALRQVLVNRYYGNVRPSGRRESLTSFGNGPLSAGGPGKPGGGGGGSGSSSMSRGEMSLAEVQCHLDKEGASNLVIDLIMNASSDRVFHESILLAIALLEGGNTTIQHSFFCRLTEDKKSEKFFKVFYDRMKVAQQEIKATVTVNTSDLGNKKKDDEVDRDAPSRKKAKEPTTQITEEVRDQLLEASAATRKAFTTFRREADPDDHYQPGEGTQATADKAKDDLEMSAVITIMQPILRFLQLLCENHNRDLQNFLRCQNNKTNYNLVCETLQFLDCICGSTTGGLGLLGLYINEKNVALINQTLESLTEYCQGPCHENQNCIATHESNGIDIITALILNDINPLGKKRMDLVLELKNNASKLLLAIMESRHDSENAERILYNMRPKELVEVIKKAYMQGEVEFEDGENGEDGAASPRNVGHNIYILAHQLARHNKELQSMLKPGGQVDGDEALEFYAKHTAQIEIVRLDRTMEQIVFPVPSICEFLTKESKLRIYYTTERDEQGSKINDFFLRSEDLFNEMNWQKKLRAQPVLYWCARNMSFWSSISFNLAVLMNLLVAFFYPFKGVRGGTLEPHWSGLLWTAMLISLAIVIALPKPHGIRALIASTILRLIFSVGLQPTLFLLGAFNVCNKIIFLMSFVGNCGTFTRGYRAMVLDVEFLYHLLYLVICAMGLFVHEFFYSLLLFDLVYREETLLNVIKSVTRNGRSIILTAVLALILVYLFSIVGYLFFKDDFILEVDRLPNETAVPETGESLASEFLFSDVCRVESGENCSSPAPREELVPAEETEQDKEHTCETLLMCIVTVLSHGLRSGGGVGDVLRKPSKEEPLFAARVIYDLLFFFMVIIIVLNLIFGVIIDTFADLRSEKQKKEEILKTTCFICGLERDKFDNKTVTFEEHIKEEHNMWHYLCFIVLVKVKDSTEYTGPESYVAEMIKERNLDWFPRMRAMSLVSSDSEGEQNELRNLQEKLESTMKLVTNLSGQLSELKDQMTEQRKQKQRIGLLGHPPHMNVNPQQPA Show more |
Gene and Protein Information
| Species | Gene ID | Gene Symbol | Gene Name | Uniprot |
|---|---|---|---|---|
| HUMAN | 3708 | ITPR1 | Inositol 1,4,5-trisphosphate receptor type 1 | Q14643 |
| MOUSE | 16438 | Itpr1 | Uncharacterized protein | Q3UVA1 |
| MOUSE | Itpr1 | Inositol 1,4,5-trisphosphate receptor type 1 | A0A0N4SVN2 | |
| MOUSE | 16438 | Itpr1 | Uncharacterized protein | Q8C7X9 |
| MOUSE | 16438 | Itpr1 | Uncharacterized protein | Q8C8N0 |
| MOUSE | Itpr1 | Itpr1 protein | Q6NV80 | |
| MOUSE | Itpr1 | Inositol 1,4,5-trisphosphate receptor type 1 | A0A0N4SWH7 | |
| MOUSE | Itpr1 | Inositol 1,4,5-trisphosphate receptor type 1 | A0A0N4SW22 | |
| MOUSE | Itpr1 | Inositol 1,4,5-trisphosphate receptor type 1 | A0A1D5RLA1 | |
| MOUSE | Itpr1 | Inositol 1,4,5-trisphosphate receptor type 1 | A0A0N4SWI0 | |
| MOUSE | 16438 | Itpr1 | Uncharacterized protein | Q8BQN0 |
| MOUSE | 16438 | Itpr1 | Inositol 1,4,5-trisphosphate receptor type 1 | P11881 |
| RAT | Itpr1 | Inositol 1,4,5-trisphosphate receptor type 1 | A0A0G2KAH9 | |
| RAT | 25262 | Itpr1 | Itpr1 protein | Q5BJS8 |
| RAT | 25262 | Itpr1 | Inositol 1,4,5-trisphosphate receptor type 1 | F1LQX8 |
| RAT | Itpr1 | Inositol 1,4,5-trisphosphate receptor type 1 | F1LNT1 | |
| RAT | 25262 | Itpr1 | Inositol 1,4,5-trisphosphate receptor type 1 | A0A0A0MY31 |
| RAT | 25262 | Itpr1 | Inositol 1,4,5-trisphosphate receptor type 1 | C7E1V2 |
| RAT | 25262 | Itpr1 | Inositol 1,4,5-trisphosphate receptor type 1 | P29994 |
Protein Classes
PANTHER Classes
protein / transporter / ion channel / Inositol 1,4,5-trisphosphate receptor type 1
protein / transporter / ligand-gated ion channel / Inositol 1,4,5-trisphosphate receptor type 1
protein / transporter / receptor / Inositol 1,4,5-trisphosphate receptor type 1
protein / transporter / ion channel / Inositol 1,4,5-trisphosphate receptor type 1
protein / transporter / ligand-gated ion channel / Inositol 1,4,5-trisphosphate receptor type 1
protein / transporter / receptor / Inositol 1,4,5-trisphosphate receptor type 1
DTO Classes
protein / Ion channel / Ryanodine-inositol 1,4,5-triphosphate receptor calcium channel (rir-cac) family / Inositol 1,4,5-trisphosphate receptor type 1
protein / Ion channel / Ryanodine-inositol 1,4,5-triphosphate receptor calcium channel (rir-cac) family / Inositol 1,4,5-trisphosphate receptor type 1
Associated Recombinant Proteins
| Name | Specification and purity | Expression system | Protein label | Activity | View Details |
|---|
Associated Antibodies
| Name | Specifications | Species reactivity | species | Application | View Details |
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Associated Approved Drugs
Associated Active Ligands
Associated Diseases
| Name | Disease Type | Mondoid |
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Pathway
| Data Source | Name | Explore more targets | Explore in Source |
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Source: DataSourcesLicenses.xlsx