| Description | Inositol 1,4,5-trisphosphate receptor type 3 |
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Gene and Protein Information
| Gene ID | 3710 |
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| Uniprot Accession IDs | Q14649 Q5TAQ2 |
| Ensembl ID | ENSP00000363435 |
| Symbol | IP3R IP3R3 |
| Family | Belongs to the InsP3 receptor family. |
| Sequence | MSEMSSFLHIGDIVSLYAEGSVNGFISTLGLVDDRCVVEPAAGDLDNPPKKFRDCLFKVCPMNRYSAQKQYWKAKQTKQDKEKIADVVLLQKLQHAAQMEQKQNDTENKKVHGDVVKYGSVIQLLHMKSNKYLTVNKRLPALLEKNAMRVTLDATGNEGSWLFIQPFWKLRSNGDNVVVGDKVILNPVNAGQPLHASNYELSDNAGCKEVNSVNCNTSWKINLFMQFRDHLEEVLKGGDVVRLFHAEQEKFLTCDEYKGKLQVFLRTTLRQSATSATSSNALWEVEVVHHDPCRGGAGHWNGLYRFKHLATGNYLAAEENPSYKGDASDPKAAGMGAQGRTGRRNAGEKIKYCLVAVPHGNDIASLFELDPTTLQKTDSFVPRNSYVRLRHLCTNTWIQSTNVPIDIEEERPIRLMLGTCPTKEDKEAFAIVSVPVSEIRDLDFANDASSMLASAVEKLNEGFISQNDRRFVIQLLEDLVFFVSDVPNNGQNVLDIMVTKPNRERQKLMREQNILKQVFGILKAPFREKGGEGPLVRLEELSDQKNAPYQHMFRLCYRVLRHSQEDYRKNQEHIAKQFGMMQSQIGYDILAEDTITALLHNNRKLLEKHITKTEVETFVSLVRKNREPRFLDYLSDLCVSNHIAIPVTQELICKCVLDPKNSDILIRTELRPVKEMAQSHEYLSIEYSEEEVWLTWTDKNNEHHEKSVRQLAQEARAGNAHDENVLSYYRYQLKLFARMCLDRQYLAIDEISQQLGVDLIFLCMADEMLPFDLRASFCHLMLHVHVDRDPQELVTPVKFARLWTEIPTAITIKDYDSNLNASRDDKKNKFANTMEFVEDYLNNVVSEAVPFANEEKNKLTFEVVSLAHNLIYFGFYSFSELLRLTRTLLGIIDCVQGPPAMLQAYEDPGGKNVRRSIQGVGHMMSTMVLSRKQSVFSAPSLSAGASAAEPLDRSKFEENEDIVVMETKLKILEILQFILNVRLDYRISYLLSVFKKEFVEVFPMQDSGADGTAPAFDSTTANMNLDRIGEQAEAMFGVGKTSSMLEVDDEGGRMFLRVLIHLTMHDYAPLVSGALQLLFKHFSQRQEAMHTFKQVQLLISAQDVENYKVIKSELDRLRTMVEKSELWVDKKGSGKGEEVEAGAAKDKKERPTDEEGFLHPPGEKSSENYQIVKGILERLNKMCGVGEQMRKKQQRLLKNMDAHKVMLDLLQIPYDKGDAKMMEILRYTHQFLQKFCAGNPGNQALLHKHLHLFLTPGLLEAETMQHIFLNNYQLCSEISEPVLQHFVHLLATHGRHVQYLDFLHTVIKAEGKYVKKCQDMIMTELTNAGDDVVVFYNDKASLAHLLDMMKAARDGVEDHSPLMYHISLVDLLAACAEGKNVYTEIKCTSLLPLEDVVSVVTHEDCITEVKMAYVNFVNHCYVDTEVEMKEIYTSNHIWTLFENFTLDMARVCSKREKRVADPTLEKYVLSVVLDTINAFFSSPFSENSTSLQTHQTIVVQLLQSTTRLLECPWLQQQHKGSVEACIRTLAMVAKGRAILLPMDLDAHISSMLSSGASCAAAAQRNASSYKATTRAFPRVTPTANQWDYKNIIEKLQDIITALEERLKPLVQAELSVLVDVLHWPELLFLEGSEAYQRCESGGFLSKLIQHTKDLMESEEKLCIKVLRTLQQMLLKKTKYGDRGNQLRKMLLQNYLQNRKSTSRGDLPDPIGTGLDPDWSAIAATQCRLDKEGATKLVCDLITSTKNEKIFQESIGLAIHLLDGGNTEIQKSFHNLMMSDKKSERFFKVLHDRMKRAQQETKSTVAVNMNDLGSQPHEDREPVDPTTKGRVASFSIPGSSSRYSLGPSLRRGHEVSERVQSSEMGTSVLIMQPILRFLQLLCENHNRDLQNFLRCQNNKTNYNLVCETLQFLDIMCGSTTGGLGLLGLYINEDNVGLVIQTLETLTEYCQGPCHENQTCIVTHESNGIDIITALILNDISPLCKYRMDLVLQLKDNASKLLLALMESRHDSENAERILISLRPQELVDVIKKAYLQEEERENSEVSPREVGHNIYILALQLSRHNKQLQHLLKPVKRIQEEEAEGISSMLSLNNKQLSQMLKSSAPAQEEEEDPLAYYENHTSQIEIVRQDRSMEQIVFPVPGICQFLTEETKHRLFTTTEQDEQGSKVSDFFDQSSFLHNEMEWQRKLRSMPLIYWFSRRMTLWGSISFNLAVFINIIIAFFYPYMEGASTGVLDSPLISLLFWILICFSIAALFTKRYSIRPLIVALILRSIYYLGIGPTLNILGALNLTNKIVFVVSFVGNRGTFIRGYKAMVMDMEFLYHVGYILTSVLGLFAHELFYSILLFDLIYREETLFNVIKSVTRNGRSILLTALLALILVYLFSIVGFLFLKDDFILEVDRLPNNHSTASPLGMPHGAAAFVDTCSGDKMDCVSGLSVPEVLEEDRELDSTERACDTLLMCIVTVMNHGLRNGGGVGDILRKPSKDESLFPARVVYDLLFFFIVIIIVLNLIFGVIIDTFADLRSEKQKKEEILKTTCFICGLERDKFDNKTVSFEEHIKLEHNMWNYLYFIVLVRVKNKTDYTGPESYVAQMIKNKNLDWFPRMRAMSLVSNEGEGEQNEIRILQDKLNSTMKLVSHLTAQLNELKEQMTEQRKRRQRLGFVDVQNCISR Show more |
Homologous gene and protein info.
| Species | Gene ID | Gene Symbol | Name | Tax ID | Other Gene ID | Sources |
|---|---|---|---|---|---|---|
| Chimp | 462618 | ITPR3 | inositol 1,4,5-trisphosphate receptor type 3 | 9598 | VGNC:7896 | Inparanoid, OMA, EggNOG |
| Mouse | 16440 | Itpr3 | inositol 1,4,5-triphosphate receptor 3 | 10090 | MGI:96624 | Inparanoid, OMA, EggNOG |
| Rat | 25679 | Itpr3 | inositol 1,4,5-trisphosphate receptor, type 3 | 10116 | RGD:2934 | Inparanoid, OMA |
| Dog | 481746 | ITPR3 | inositol 1,4,5-trisphosphate receptor type 3 | 9615 | VGNC:42159 | Inparanoid, OMA |
| Horse | 100053019 | ITPR3 | inositol 1,4,5-trisphosphate receptor type 3 | 9796 | VGNC:19196 | Inparanoid, OMA |
| Cow | 281879 | ITPR3 | inositol 1,4,5-trisphosphate receptor type 3 | 9913 | VGNC:30348 | Inparanoid, OMA |
| Pig | 100155015 | ITPR3 | inositol 1,4,5-trisphosphate receptor type 3 | 9823 | Inparanoid, OMA | |
| Opossum | 100025596 | ITPR3 | inositol 1,4,5-trisphosphate receptor type 3 | 13616 | Inparanoid, OMA | |
| Zebrafish | 794666 | itpr3 | inositol 1,4,5-trisphosphate receptor, type 3 | 7955 | ZDB-GENE-070605-1 | Inparanoid, OMA |
| C. elegans | 177546 | itr-1 | Inositol 1,4,5-trisphosphate receptor itr-1 | 6239 | Inparanoid, OMA |
Protein Classes
PANTHER Classes
protein / transporter / ion channel / Inositol 1,4,5-trisphosphate receptor type 3
protein / transporter / ligand-gated ion channel / Inositol 1,4,5-trisphosphate receptor type 3
protein / transporter / receptor / Inositol 1,4,5-trisphosphate receptor type 3
protein / transporter / ion channel / Inositol 1,4,5-trisphosphate receptor type 3
protein / transporter / ligand-gated ion channel / Inositol 1,4,5-trisphosphate receptor type 3
protein / transporter / receptor / Inositol 1,4,5-trisphosphate receptor type 3
DTO Classes
protein / Ion channel / Ryanodine-inositol 1,4,5-triphosphate receptor calcium channel (rir-cac) family / Inositol 1,4,5-trisphosphate receptor type 3
protein / Ion channel / Ryanodine-inositol 1,4,5-triphosphate receptor calcium channel (rir-cac) family / Inositol 1,4,5-trisphosphate receptor type 3
Associated Recombinant Proteins
| Name | Specification and purity | Expression system | Protein label | Activity | View Details |
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Associated Antibodies
| Name | Specifications | Species reactivity | species | Application | View Details |
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Associated Approved Drugs
Associated Active Ligands
Associated Diseases
| Name | Disease Type | Mondoid |
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Pathway
| Data Source | Name | Explore more targets | Explore in Source |
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