Protein or Target Summary
General transcription and DNA repair factor IIH helicase subunit XPD
| Gene ID | 2068 |
|---|---|
| uniprot | P18074 |
| Gene Name | ERCC2 |
| Ensernbl ID | ENSP00000375809 |
| Family | Belongs to the helicase family. RAD3/XPD subfamily. |
| Sequence | MKLNVDGLLVYFPYDYIYPEQFSYMRELKRTLDAKGHGVLEMPSGTGKTVSLLALIMAYQRAYPLEVTKLIYCSRTVPEIEKVIEELRKLLNFYEKQEGEKLPFLGLALSSRKNLCIHPEVTPLRFGKDVDGKCHSLTASYVRAQYQHDTSLPHCRFYEEFDAHGREVPLPAGIYNLDDLKALGRRQGWCPYFLARYSILHANVVVYSYHYLLDPKIADLVSKELARKAVVVFDEAHNIDNVCIDSMSVNLTRRTLDRCQGNLETLQKTVLRIKETDEQRLRDEYRRLVEGLREASAARETDAHLANPVLPDEVLQEAVPGSIRTAEHFLGFLRRLLEYVKWRLRVQHVVQESPPAFLSGLAQRVCIQRKPLRFCAERLRSLLHTLEITDLADFSPLTLLANFATLVSTYAKGFTIIIEPFDDRTPTIANPILHFSCMDASLAIKPVFERFQSVIITSGTLSPLDIYPKILDFHPVTMATFTMTLARVCLCPMIIGRGNDQVAISSKFETREDIAVIRNYGNLLLEMSAVVPDGIVAFFTSYQYMESTVASWYEQGILENIQRNKLLFIETQDGAETSVALEKYQEACENGRGAILLSVARGKVSEGIDFVHHYGRAVIMFGVPYVYTQSRILKARLEYLRDQFQIRENDFLTFDAMRHAAQCVGRAIRGKTDYGLMVFADKRFARGDKRGKLPRWIQEHLTDANLNLTVDEGVQVAKYFLRQMAQPFHREDQLGLSLLSLEQLESEETLKRIEQIAQQL Show more |
Gene and Protein Information
| Species | Gene ID | Gene Symbol | Gene Name | Uniprot |
|---|---|---|---|---|
| HUMAN | 2068 | ERCC2 | General transcription and DNA repair factor IIH helicase subunit XPD | P18074 |
| MOUSE | 13871 | Ercc2 | General transcription and DNA repair factor IIH helicase subunit XPD | O08811 |
| MOUSE | Ercc2 | Ercc2 protein | Q8K223 | |
| MOUSE | Ercc2 | Uncharacterized protein | Q3UKK7 | |
| MOUSE | Ercc2 | General transcription and DNA repair factor IIH helicase subunit XPD | D3Z700 | |
| MOUSE | Ercc2 | General transcription and DNA repair factor IIH helicase subunit XPD | E9Q6K1 | |
| MOUSE | Ercc2 | General transcription and DNA repair factor IIH helicase subunit XPD | F6YA33 | |
| RAT | 308415 | Ercc2 | ERCC excision repair 2, TFIIH core complex helicase subunit | D3ZEG9 |
Protein Classes
PANTHER Classes
protein / nucleic acid binding / DNA binding protein / TFIIH basal transcription factor complex helicase XPD subunit
protein / nucleic acid binding / DNA helicase / TFIIH basal transcription factor complex helicase XPD subunit
protein / nucleic acid binding / helicase / TFIIH basal transcription factor complex helicase XPD subunit
protein / nucleic acid binding / DNA binding protein / TFIIH basal transcription factor complex helicase XPD subunit
protein / nucleic acid binding / DNA helicase / TFIIH basal transcription factor complex helicase XPD subunit
protein / nucleic acid binding / helicase / TFIIH basal transcription factor complex helicase XPD subunit
DTO Classes
protein / Enzyme / Helicase / DNA helicase / TFIIH basal transcription factor complex helicase XPD subunit
protein / Enzyme / Helicase / DNA helicase / TFIIH basal transcription factor complex helicase XPD subunit
Associated Recombinant Proteins
| Name | Specification and purity | Expression system | Protein label | Activity | View Details |
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Associated Antibodies
| Name | Specifications | Species reactivity | species | Application | View Details |
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Associated Approved Drugs
Associated Active Ligands
Associated Diseases
| Name | Disease Type | Mondoid |
|---|
Pathway
| Data Source | Name | Explore more targets | Explore in Source |
|---|
Source: TCRDv6_DataSourcesLicenses.xlsx