ERCC2
| Description | General transcription and DNA repair factor IIH helicase subunit XPD |
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Gene and Protein Information
| Gene ID | 2068 |
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| Uniprot Accession IDs | Q2TB78 Q2YDY2 Q7KZU6 Q8N721 TFIIH subunit XPD |
| Ensembl ID | ENSP00000375809 |
| Symbol | XPD XPDC EM9 TTD XPD TTD1 COFS2 TFIIH |
| Family | Belongs to the helicase family. RAD3/XPD subfamily. |
| Sequence | MKLNVDGLLVYFPYDYIYPEQFSYMRELKRTLDAKGHGVLEMPSGTGKTVSLLALIMAYQRAYPLEVTKLIYCSRTVPEIEKVIEELRKLLNFYEKQEGEKLPFLGLALSSRKNLCIHPEVTPLRFGKDVDGKCHSLTASYVRAQYQHDTSLPHCRFYEEFDAHGREVPLPAGIYNLDDLKALGRRQGWCPYFLARYSILHANVVVYSYHYLLDPKIADLVSKELARKAVVVFDEAHNIDNVCIDSMSVNLTRRTLDRCQGNLETLQKTVLRIKETDEQRLRDEYRRLVEGLREASAARETDAHLANPVLPDEVLQEAVPGSIRTAEHFLGFLRRLLEYVKWRLRVQHVVQESPPAFLSGLAQRVCIQRKPLRFCAERLRSLLHTLEITDLADFSPLTLLANFATLVSTYAKGFTIIIEPFDDRTPTIANPILHFSCMDASLAIKPVFERFQSVIITSGTLSPLDIYPKILDFHPVTMATFTMTLARVCLCPMIIGRGNDQVAISSKFETREDIAVIRNYGNLLLEMSAVVPDGIVAFFTSYQYMESTVASWYEQGILENIQRNKLLFIETQDGAETSVALEKYQEACENGRGAILLSVARGKVSEGIDFVHHYGRAVIMFGVPYVYTQSRILKARLEYLRDQFQIRENDFLTFDAMRHAAQCVGRAIRGKTDYGLMVFADKRFARGDKRGKLPRWIQEHLTDANLNLTVDEGVQVAKYFLRQMAQPFHREDQLGLSLLSLEQLESEETLKRIEQIAQQL Show more |
Homologous gene and protein info.
| Species | Gene ID | Gene Symbol | Name | Tax ID | Other Gene ID | Sources |
|---|---|---|---|---|---|---|
| Chimp | 456124 | ERCC2 | ERCC excision repair 2, TFIIH core complex helicase subunit | 9598 | VGNC:7479 | OMA, EggNOG |
| Macaque | 715485 | ERCC2 | ERCC excision repair 2, TFIIH core complex helicase subunit | 9544 | Inparanoid, OMA, EggNOG | |
| Mouse | 13871 | Ercc2 | excision repair cross-complementing rodent repair deficiency, complementation group 2 | 10090 | MGI:95413 | Inparanoid, OMA, EggNOG |
| Rat | 308415 | Ercc2 | ERCC excision repair 2, TFIIH core complex helicase subunit | 10116 | RGD:1309109 | Inparanoid, OMA, EggNOG |
| Dog | 493995 | ERCC2 | ERCC excision repair 2, TFIIH core complex helicase subunit | 9615 | VGNC:40442 | Inparanoid, OMA, EggNOG |
| Cow | 100125238 | ERCC2 | ERCC excision repair 2, TFIIH core complex helicase subunit | 9913 | VGNC:28569 | Inparanoid, OMA, EggNOG |
| Opossum | 100012006 | ERCC2 | ERCC excision repair 2, TFIIH core complex helicase subunit | 13616 | Inparanoid, OMA, EggNOG | |
| Xenopus | ercc2 | excision repair cross-complementation group 2 [Source:Xenbase;Acc:XB-GENE-949792] | 8364 | OMA, EggNOG | ||
| Zebrafish | 393900 | ercc2 | excision repair cross-complementation group 2 | 7955 | ZDB-GENE-040426-997 | Inparanoid, OMA, EggNOG |
| Fruitfly | 37414 | Xpd | Xeroderma pigmentosum D | 7227 | FBgn0261850 | Inparanoid, EggNOG |
| S.cerevisiae | 856918 | RAD3 | TFIIH/NER complex ATP-dependent 5'-3' DNA helicase subunit RAD3 | 4932 | S000000973 | Inparanoid, OMA, EggNOG |
Protein Classes
PANTHER Classes
protein / nucleic acid binding / DNA binding protein / TFIIH basal transcription factor complex helicase XPD subunit
protein / nucleic acid binding / DNA helicase / TFIIH basal transcription factor complex helicase XPD subunit
protein / nucleic acid binding / helicase / TFIIH basal transcription factor complex helicase XPD subunit
protein / nucleic acid binding / DNA binding protein / TFIIH basal transcription factor complex helicase XPD subunit
protein / nucleic acid binding / DNA helicase / TFIIH basal transcription factor complex helicase XPD subunit
protein / nucleic acid binding / helicase / TFIIH basal transcription factor complex helicase XPD subunit
DTO Classes
protein / Enzyme / Helicase / DNA helicase / TFIIH basal transcription factor complex helicase XPD subunit
protein / Enzyme / Helicase / DNA helicase / TFIIH basal transcription factor complex helicase XPD subunit
Associated Recombinant Proteins
| Name | Specification and purity | Expression system | Protein label | Activity | View Details |
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Associated Antibodies
| Name | Specifications | Species reactivity | species | Application | View Details |
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Associated Approved Drugs
Associated Active Ligands
Associated Diseases
| Name | Disease Type | Mondoid |
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Pathway
| Data Source | Name | Explore more targets | Explore in Source |
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