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ERCC5
| Description | DNA repair protein complementing XP-G cells |
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Gene and Protein Information
| Gene ID | 2073 |
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| Uniprot Accession IDs | A6NGT4 Q5JUS4 Q5JUS5 Q7Z2V3 Q8IZL6 Q8N1B7 Q9HD59 Q9HD60 |
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| Ensembl ID | ENSP00000347978 |
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| Symbol | ERCM2 XPG XPGC XPG UVDR XPGC COFS3 ERCM2 ERCC5-201 |
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| Family | Belongs to the XPG/RAD2 endonuclease family. XPG subfamily. |
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| Sequence | MGVQGLWKLLECSGRQVSPEALEGKILAVDISIWLNQALKGVRDRHGNSIENPHLLTLFHRLCKLLFFRIRPIFVFDGDAPLLKKQTLVKRRQRKDLASSDSRKTTEKLLKTFLKRQAIKTAFRSKRDEALPSLTQVRRENDLYVLPPLQEEEKHSSEEEDEKEWQERMNQKQALQEEFFHNPQAIDIESEDFSSLPPEVKHEILTDMKEFTKRRRTLFEAMPEESDDFSQYQLKGLLKKNYLNQHIEHVQKEMNQQHSGHIRRQYEDEGGFLKEVESRRVVSEDTSHYILIKGIQAKTVAEVDSESLPSSSKMHGMSFDVKSSPCEKLKTEKEPDATPPSPRTLLAMQAALLGSSSEEELESENRRQARGRNAPAAVDEGSISPRTLSAIKRALDDDEDVKVCAGDDVQTGGPGAEEMRINSSTENSDEGLKVRDGKGIPFTATLASSSVNSAEEHVASTNEGREPTDSVPKEQMSLVHVGTEAFPISDESMIKDRKDRLPLESAVVRHSDAPGLPNGRELTPASPTCTNSVSKNETHAEVLEQQNELCPYESKFDSSLLSSDDETKCKPNSASEVIGPVSLQETSSIVSVPSEAVDNVENVVSFNAKEHENFLETIQEQQTTESAGQDLISIPKAVEPMEIDSEESESDGSFIEVQSVISDEELQAEFPETSKPPSEQGEEELVGTREGEAPAESESLLRDNSERDDVDGEPQEAEKDAEDSLHEWQDINLEELETLESNLLAQQNSLKAQKQQQERIAATVTGQMFLESQELLRLFGIPYIQAPMEAEAQCAILDLTDQTSGTITDDSDIWLFGARHVYRNFFNKNKFVEYYQYVDFHNQLGLDRNKLINLAYLLGSDYTEGIPTVGCVTAMEILNEFPGHGLEPLLKFSEWWHEAQKNPKIRPNPHDTKVKKKLRTLQLTPGFPNPAVAEAYLKPVVDDSKGSFLWGKPDLDKIREFCQRYFGWNRTKTDESLFPVLKQLDAQQTQLRIDSFFRLAQQEKEDAKRIKSQRLNRAVTCMLRKEKEAAASEIEAVSVAMEKEFELLDKAKGKTQKRGITNTLEESSSLKRKRLSDSKGKNTCGGFLGETCLSESSDGSSSEDAESSSLMNVQRRTAAKEPKTSASDSQNSVKEAPVKNGGATTSSSSDSDDDGGKEKMVLVTARSVFGKKRRKLRRARGRKRKT Show more |
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Homologous gene and protein info.
| Species | Gene ID | Gene Symbol | Name | Tax ID | Other Gene ID | Sources |
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| Chimp | | BIVM-ERCC5 | BIVM-ERCC5 readthrough [Source:HGNC Symbol;Acc:HGNC:43690] | 9598 | | OMA, EggNOG |
| Macaque | | BIVM-ERCC5 | BIVM-ERCC5 readthrough [Source:HGNC Symbol;Acc:HGNC:43690] | 9544 | | OMA, EggNOG |
| Mouse | 22592 | Ercc5 | excision repair cross-complementing rodent repair deficiency, complementation group 5 | 10090 | MGI:103582 | Inparanoid, OMA, EggNOG |
| Rat | 301382 | Ercc5 | ERCC excision repair 5, endonuclease | 10116 | RGD:1586176 | Inparanoid, OMA, EggNOG |
| Dog | 100855935 | ERCC5 | ERCC excision repair 5, endonuclease | 9615 | | OMA, EggNOG |
| Horse | 102147743 | LOC102147743 | basic immunoglobulin-like variable motif-containing protein | 9796 | | OMA, EggNOG |
| Cow | 509602 | ERCC5 | ERCC excision repair 5, endonuclease | 9913 | | Inparanoid, OMA, EggNOG |
| Chicken | 428019 | ERCC5 | ERCC excision repair 5, endonuclease | 9031 | CGNC:12652 | Inparanoid, OMA, EggNOG |
| Xenopus | 780380 | bivm | basic, immunoglobulin-like variable motif containing | 8364 | XB-GENE-976555 | OMA, EggNOG |
| Zebrafish | 541502 | ercc5 | excision repair cross-complementation group 5 | 7955 | ZDB-GENE-050327-28 | Inparanoid, OMA, EggNOG |
| C. elegans | 186441 | xpg-1 | XPG (Xeroderma Pigmentosum group G) DNA repair gene homolog | 6239 | | Inparanoid, EggNOG |
| S.cerevisiae | 853174 | RAD2 | ssDNA endodeoxyribonuclease RAD2 | 4932 | S000003490 | Inparanoid, OMA, EggNOG |
Associated Recombinant Proteins
| Name | Specification and purity | Expression system | Protein label | Activity | View Details |
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Associated Antibodies
| Name | Specifications | Species reactivity | species | Application | View Details |
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Associated Approved Drugs
Associated Active Ligands
Pathway
| Data Source | Name | Explore more targets | Explore in Source |
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