Protein or Target Summary
Serine/threonine-protein kinase/endoribonuclease IRE1
| Gene ID | 2081 |
|---|---|
| uniprot | O75460 |
| Gene Name | ERN1 |
| Ensernbl ID | ENSP00000401445 |
| Family | Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. |
| Sequence | MPARRLLLLLTLLLPGLGIFGSTSTVTLPETLLFVSTLDGSLHAVSKRTGSIKWTLKEDPVLQVPTHVEEPAFLPDPNDGSLYTLGSKNNEGLTKLPFTIPELVQASPCRSSDGILYMGKKQDIWYVIDLLTGEKQQTLSSAFADSLCPSTSLLYLGRTEYTITMYDTKTRELRWNATYFDYAASLPEDDVDYKMSHFVSNGDGLVVTVDSESGDVLWIQNYASPVVAFYVWQREGLRKVMHINVAVETLRYLTFMSGEVGRITKWKYPFPKETEAKSKLTPTLYVGKYSTSLYASPSMVHEGVAVVPRGSTLPLLEGPQTDGVTIGDKGECVITPSTDVKFDPGLKSKNKLNYLRNYWLLIGHHETPLSASTKMLERFPNNLPKHRENVIPADSEKKSFEEVINLVDQTSENAPTTVSRDVEEKPAHAPARPEAPVDSMLKDMATIILSTFLLIGWVAFIITYPLSMHQQQQLQHQQFQKELEKIQLLQQQQQQLPFHPPGDTAQDGELLDTSGPYSESSGTSSPSTSPRASNHSLCSGSSASKAGSSPSLEQDDGDEETSVVIVGKISFCPKDVLGHGAEGTIVYRGMFDNRDVAVKRILPECFSFADREVQLLRESDEHPNVIRYFCTEKDRQFQYIAIELCAATLQEYVEQKDFAHLGLEPITLLQQTTSGLAHLHSLNIVHRDLKPHNILISMPNAHGKIKAMISDFGLCKKLAVGRHSFSRRSGVPGTEGWIAPEMLSEDCKENPTYTVDIFSAGCVFYYVISEGSHPFGKSLQRQANILLGACSLDCLHPEKHEDVIARELIEKMIAMDPQKRPSAKHVLKHPFFWSLEKQLQFFQDVSDRIEKESLDGPIVKQLERGGRAVVKMDWRENITVPLQTDLRKFRTYKGGSVRDLLRAMRNKKHHYRELPAEVRETLGSLPDDFVCYFTSRFPHLLAHTYRAMELCSHERLFQPYYFHEPPEPQPPVTPDAL Show more |
Gene and Protein Information
| Species | Gene ID | Gene Symbol | Gene Name | Uniprot |
|---|---|---|---|---|
| HUMAN | 2081 | ERN1 | Serine/threonine-protein kinase/endoribonuclease IRE1 | O75460 |
| MOUSE | 78943 | Ern1 | Serine/threonine-protein kinase/endoribonuclease IRE1 | Q9EQY0 |
| MOUSE | Ern1 | Serine/threonine-protein kinase/endoribonuclease IRE1 | B1ARJ5 | |
| MOUSE | Ern1 | Serine/threonine-protein kinase/endoribonuclease IRE1 | B1ATQ7 | |
| MOUSE | Ern1 | Endoplasmic reticulum (ER) to nucleus signalling 1, isoform CRA_b | Q3TBZ5 | |
| RAT | 498013 | Ern1 | Endoplasmic reticulum to nucleus-signaling 1 | A0A0G2K2H4 |
| RAT | 498013 | Ern1 | Endoplasmic reticulum to nucleus-signaling 1 | F1LSY7 |
Protein Classes
PANTHER Classes
protein / protein kinase / Serine/threonine-protein kinase/endoribonuclease ire1
protein / transferase / Serine/threonine-protein kinase/endoribonuclease ire1
protein / kinase / Serine/threonine-protein kinase/endoribonuclease ire1
protein / protein kinase / Serine/threonine-protein kinase/endoribonuclease ire1
protein / transferase / Serine/threonine-protein kinase/endoribonuclease ire1
protein / kinase / Serine/threonine-protein kinase/endoribonuclease ire1
DTO Classes
protein / Kinase / Protein kinase / Other group / IRE family / Serine/threonine-protein kinase/endoribonuclease ire1
protein / Kinase / Protein kinase / Other group / IRE family / Serine/threonine-protein kinase/endoribonuclease ire1
Associated Recombinant Proteins
| Name | Specification and purity | Expression system | Protein label | Activity | View Details |
|---|
Associated Antibodies
| Name | Specifications | Species reactivity | species | Application | View Details |
|---|
Associated Approved Drugs
Associated Active Ligands
Associated Diseases
| Name | Disease Type | Mondoid |
|---|
Pathway
| Data Source | Name | Explore more targets | Explore in Source |
|---|
Source: DataSourcesLicenses.xlsx