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PLAT
| Description | Tissue-type plasminogen activator |
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Gene and Protein Information
| Gene ID | 5327 |
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| Uniprot Accession IDs | A8K022 B2R8E8 Q15103 Q503B0 Q6PJA5 Q7Z7N2 Q86YK8 Q9BU99 Q9BZW1 t-PA |
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| Ensembl ID | ENSP00000220809 |
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| Symbol | TPA T-PA |
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| Family | Belongs to the peptidase S1 family. |
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| Sequence | MDAMKRGLCCVLLLCGAVFVSPSQEIHARFRRGARSYQVICRDEKTQMIYQQHQSWLRPVLRSNRVEYCWCNSGRAQCHSVPVKSCSEPRCFNGGTCQQALYFSDFVCQCPEGFAGKCCEIDTRATCYEDQGISYRGTWSTAESGAECTNWNSSALAQKPYSGRRPDAIRLGLGNHNYCRNPDRDSKPWCYVFKAGKYSSEFCSTPACSEGNSDCYFGNGSAYRGTHSLTESGASCLPWNSMILIGKVYTAQNPSAQALGLGKHNYCRNPDGDAKPWCHVLKNRRLTWEYCDVPSCSTCGLRQYSQPQFRIKGGLFADIASHPWQAAIFAKHRRSPGERFLCGGILISSCWILSAAHCFQERFPPHHLTVILGRTYRVVPGEEEQKFEVEKYIVHKEFDDDTYDNDIALLQLKSDSSRCAQESSVVRTVCLPPADLQLPDWTECELSGYGKHEALSPFYSERLKEAHVRLYPSSRCTSQHLLNRTVTDNMLCAGDTRSGGPQANLHDACQGDSGGPLVCLNDGRMTLVGIISWGLGCGQKDVPGVYTKVTNYLDWIRDNMRP Show more |
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Homologous gene and protein info.
| Species | Gene ID | Gene Symbol | Name | Tax ID | Other Gene ID | Sources |
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| Chimp | 472748 | PLAT | plasminogen activator, tissue type | 9598 | VGNC:3003 | OMA, EggNOG |
| Macaque | 704475 | PLAT | plasminogen activator, tissue type | 9544 | | Inparanoid, OMA, EggNOG |
| Mouse | 18791 | Plat | plasminogen activator, tissue | 10090 | MGI:97610 | Inparanoid, OMA, EggNOG |
| Rat | 25692 | Plat | plasminogen activator, tissue type | 10116 | RGD:3342 | Inparanoid, OMA, EggNOG |
| Dog | 482840 | PLAT | plasminogen activator, tissue type | 9615 | | Inparanoid, OMA, EggNOG |
| Horse | 100050239 | PLAT | plasminogen activator, tissue type | 9796 | VGNC:21529 | Inparanoid, OMA, EggNOG |
| Cow | 281407 | PLAT | plasminogen activator, tissue type | 9913 | VGNC:32974 | Inparanoid, OMA, EggNOG |
| Pig | 397121 | PLAT | plasminogen activator, tissue type | 9823 | | Inparanoid, OMA, EggNOG |
| Opossum | 100033029 | PLAT | plasminogen activator, tissue type | 13616 | | Inparanoid, EggNOG |
| Platypus | 100078960 | PLAT | plasminogen activator, tissue type | 9258 | | Inparanoid, OMA, EggNOG |
| Chicken | 426791 | PLAT | plasminogen activator, tissue type | 9031 | CGNC:2713 | Inparanoid, OMA, EggNOG |
| Anole lizard | 100568270 | plat | plasminogen activator, tissue type | 28377 | | Inparanoid, OMA, EggNOG |
| Xenopus | 594962 | plat | plasminogen activator, tissue | 8364 | XB-GENE-1010818 | Inparanoid, OMA, EggNOG |
| Zebrafish | 100320028 | plat | plasminogen activator, tissue | 7955 | ZDB-GENE-081104-181 | Inparanoid, OMA, EggNOG |
Protein Classes
PANTHER Classes protein /
serine protease / Tissue-type plasminogen activator
protein /
protease / Tissue-type plasminogen activator
protein /
hydrolase / Tissue-type plasminogen activator
Associated Recombinant Proteins
| Name | Specification and purity | Expression system | Protein label | Activity | View Details |
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Associated Antibodies
| Name | Specifications | Species reactivity | species | Application | View Details |
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Associated Approved Drugs
Associated Active Ligands
Pathway
| Data Source | Name | Explore more targets | Explore in Source |
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