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TPH1
| Description | Tryptophan 5-hydroxylase 1 |
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Gene and Protein Information
| Gene ID | 7166 |
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| Uniprot Accession IDs | D3DQX6 O95188 O95189 Q16736 Q3KPG8 |
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| Ensembl ID | ENSP00000250018 |
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| Symbol | TPH TPRH TRPH TPRH TRPH |
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| Family | Belongs to the biopterin-dependent aromatic amino acid hydroxylase family. |
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| Sequence | MIEDNKENKDHSLERGRASLIFSLKNEVGGLIKALKIFQEKHVNLLHIESRKSKRRNSEFEIFVDCDINREQLNDIFHLLKSHTNVLSVNLPDNFTLKEDGMETVPWFPKKISDLDHCANRVLMYGSELDADHPGFKDNVYRKRRKYFADLAMNYKHGDPIPKVEFTEEEIKTWGTVFQELNKLYPTHACREYLKNLPLLSKYCGYREDNIPQLEDVSNFLKERTGFSIRPVAGYLSPRDFLSGLAFRVFHCTQYVRHSSDPFYTPEPDTCHELLGHVPLLAEPSFAQFSQEIGLASLGASEEAVQKLATCYFFTVEFGLCKQDGQLRVFGAGLLSSISELKHALSGHAKVKPFDPKITCKQECLITTFQDVYFVSESFEDAKEKMREFTKTIKRPFGVKYNPYTRSIQILKDTKSITSAMNELQHDLDVVSDALAKVSRKPSI Show more |
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Homologous gene and protein info.
| Species | Gene ID | Gene Symbol | Name | Tax ID | Other Gene ID | Sources |
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| Chimp | 466453 | TPH1 | tryptophan hydroxylase 1 | 9598 | VGNC:965 | OMA, EggNOG |
| Macaque | 695363 | TPH1 | tryptophan hydroxylase 1 | 9544 | | OMA, EggNOG |
| Mouse | 21990 | Tph1 | tryptophan hydroxylase 1 | 10090 | MGI:98796 | Inparanoid, OMA, EggNOG |
| Rat | 24848 | Tph1 | tryptophan hydroxylase 1 | 10116 | RGD:3895 | Inparanoid, OMA, EggNOG |
| Dog | 611956 | TPH1 | tryptophan hydroxylase 1 | 9615 | VGNC:47738 | Inparanoid, OMA |
| Horse | 100056614 | TPH1 | tryptophan hydroxylase 1 | 9796 | VGNC:24430 | Inparanoid, OMA |
| Cow | 781941 | TPH1 | tryptophan hydroxylase 1 | 9913 | VGNC:36249 | Inparanoid, OMA |
| Opossum | 100020009 | TPH1 | tryptophan hydroxylase 1 | 13616 | | Inparanoid, OMA |
| Platypus | 100090381 | TPH1 | tryptophan hydroxylase 1 | 9258 | | Inparanoid, OMA |
| Chicken | 395799 | TPH1 | tryptophan hydroxylase 1 | 9031 | CGNC:49485 | Inparanoid, OMA |
| Anole lizard | 100562860 | tph1 | tryptophan hydroxylase 1 | 28377 | | Inparanoid, OMA |
| Xenopus | 100497239 | tph1 | tryptophan hydroxylase 1 | 8364 | XB-GENE-996926 | Inparanoid, OMA |
| Zebrafish | 415103 | tph1b | tryptophan hydroxylase 1b | 7955 | ZDB-GENE-030805-6 | Inparanoid, OMA |
Associated Recombinant Proteins
| Name | Specification and purity | Expression system | Protein label | Activity | View Details |
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Associated Antibodies
| Name | Specifications | Species reactivity | species | Application | View Details |
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Associated Approved Drugs
Associated Active Ligands
Pathway
| Data Source | Name | Explore more targets | Explore in Source |
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