TNFSF10

DescriptionTumor necrosis factor ligand superfamily member 10

Gene and Protein Information

Gene ID8743
Uniprot Accession IDs A1Y9B3
Ensembl ID ENSP00000241261
Symbol APO2L TRAIL TL2 APO2L CD253 TRAIL Apo-2L TNLG6A
FamilyBelongs to the tumor necrosis factor family.
Sequence
MAMMEVQGGPSLGQTCVLIVIFTVLLQSLCVAVTYVYFTNELKQMQDKYSKSGIACFLKEDDSYWDPNDEESMNSPCWQVKWQLRQLVRKMILRTSEETISTVQEKQQNISPLVRERGPQRVAAHITGTRGRSNTLSSPNSKNEKALGRKINSWESSRSGHSFLSNLHLRNGELVIHEKGFYYIYSQTYFRFQEEIKENTKNDKQMVQYIYKYTSYPDPILLMKSARNSCWSKDAEYGLYSIYQGGIFELKENDRIFVSVTNEHLIDMDHEASFFGAFLVG
Homologous gene and protein info.
SpeciesGene IDGene SymbolNameTax IDOther Gene IDSources
Chimp460852TNFSF10TNF superfamily member 109598VGNC:8015OMA, EggNOG
Macaque694451TNFSF10TNF superfamily member 109544Inparanoid, OMA, EggNOG
Mouse22035Tnfsf10tumor necrosis factor (ligand) superfamily, member 1010090MGI:107414Inparanoid, OMA, EggNOG
Rat246775Tnfsf10TNF superfamily member 1010116RGD:628734Inparanoid, OMA, EggNOG
Dog100174780TNFSF10TNF superfamily member 109615VGNC:47669Inparanoid, OMA, EggNOG
Horse100064377TNFSF10TNF superfamily member 109796VGNC:24374Inparanoid, OMA, EggNOG
Cow507215TNFSF10TNF superfamily member 109913VGNC:36172Inparanoid, OMA, EggNOG
Pig406191TNFSF10TNF superfamily member 109823Inparanoid, OMA
Opossum100010299TNFSF10TNF superfamily member 1013616Inparanoid, OMA, EggNOG
Platypus100074849TNFSF10TNF superfamily member 109258Inparanoid, OMA, EggNOG
Chicken378894TNFSF10tumor necrosis factor superfamily member 109031CGNC:6980Inparanoid, OMA, EggNOG
Anole lizard100566541tnfsf10TNF superfamily member 1028377Inparanoid, OMA, EggNOG
XenopusTNFSF10TNF superfamily member 10 [Source:HGNC Symbol;Acc:HGNC:11925]8364OMA, EggNOG
Zebrafish436866tnfsf10TNF superfamily member 107955ZDB-GENE-040718-335Inparanoid, OMA, EggNOG

Protein Classes

PANTHER Classes
protein    /    signaling molecule    /    tumor necrosis factor family member    /    Tumor necrosis factor ligand superfamily member 10
DTO Classes
protein    /    Signaling    /    Cytokine    /    Tumor necrosis factor family member    /    Tumor necrosis factor ligand superfamily member 10

Associated Recombinant Proteins

NameSpecification and purityExpression systemProtein labelActivityView Details

Associated Antibodies

NameSpecificationsSpecies reactivityspeciesApplicationView Details

Associated Approved Drugs

    Associated Active Ligands

      Associated Diseases

      NameDisease TypeMondoid

      Pathway

      Data SourceNameExplore more targetsExplore in Source