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Protein or Target Summary

NAD-dependent protein deacetylase sirtuin-3, mitochondrial

Gene ID23410
uniprotQ9NTG7
Gene NameSIRT3
Ensernbl IDENSP00000372191
FamilyBelongs to the sirtuin family. Class I subfamily.
Sequence
MAFWGWRAAAALRLWGRVVERVEAGGGVGPFQACGCRLVLGGRDDVSAGLRGSHGARGEPLDPARPLQRPPRPEVPRAFRRQPRAAAPSFFFSSIKGGRRSISFSVGASSVVGSGGSSDKGKLSLQDVAELIRARACQRVVVMVGAGISTPSGIPDFRSPGSGLYSNLQQYDLPYPEAIFELPFFFHNPKPFFTLAKELYPGNYKPNVTHYFLRLLHDKGLLLRLYTQNIDGLERVSGIPASKLVEAHGTFASATCTVCQRPFPGEDIRADVMADRVPRCPVCTGVVKPDIVFFGEPLPQRFLLHVVDFPMADLLLILGTSLEVEPFASLTEAVRSSVPRLLINRDLVGPLAWHPRSRDVAQLGDVVHGVESLVELLGWTEEMRDLVQRETGKLDGPDK
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Gene and Protein Information

SpeciesGene IDGene SymbolGene NameUniprot
HUMAN23410SIRT3NAD-dependent protein deacetylase sirtuin-3, mitochondrialQ9NTG7
MOUSESirt3NAD-dependent protein deacetylaseA0A1B0GRY5
MOUSESirt3NAD-dependent protein deacetylase sirtuin-3D3YWD6
MOUSESirt3NAD-dependent protein deacetylase sirtuin-3D3YTK6
MOUSESirt3NAD-dependent protein deacetylase sirtuin-3A0A1B0GRF7
MOUSESirt3NAD-dependent protein deacetylase sirtuin-3D3YVQ5
MOUSE64384Sirt3NAD-dependent protein deacetylaseQ4FJK3
MOUSE64384Sirt3NAD-dependent protein deacetylase sirtuin-3Q8R104
RAT293615Sirt3NAD-dependent protein deacetylaseB2RZ31
RATSirt3NAD-dependent protein deacetylaseC6ZII9

Protein Classes

PANTHER Classes
protein    /    hydrolase    /    deacetylase    /    NAD-dependent protein deacetylase sirtuin-3, mitochondrial
protein    /    hydrolase    /    chromatin/chromatin-binding protein    /    NAD-dependent protein deacetylase sirtuin-3, mitochondrial
DTO Classes
protein    /    Epigenetic regulator    /    Eraser    /    Histone deacetylase    /    HDAC class III    /    NAD-dependent protein deacetylase sirtuin-3, mitochondrial

Associated Recombinant Proteins

NameSpecification and purityExpression systemProtein labelActivityView Details

Associated Antibodies

NameSpecificationsSpecies reactivityspeciesApplicationView Details

Associated Approved Drugs

    Associated Active Ligands

      Associated Diseases

      NameDisease TypeMondoid

      Pathway

      Data SourceNameExplore more targetsExplore in Source