| Description | NAD-dependent protein deacetylase sirtuin-3, mitochondrial |
|---|
Gene and Protein Information
| Gene ID | 23410 |
|---|---|
| Uniprot Accession IDs | B7Z5U6 Q9Y6E8 hSIRT3 |
| Ensembl ID | ENSP00000372191 |
| Symbol | SIR2L3 SIR2L3 |
| Family | Belongs to the sirtuin family. Class I subfamily. |
| Sequence | MAFWGWRAAAALRLWGRVVERVEAGGGVGPFQACGCRLVLGGRDDVSAGLRGSHGARGEPLDPARPLQRPPRPEVPRAFRRQPRAAAPSFFFSSIKGGRRSISFSVGASSVVGSGGSSDKGKLSLQDVAELIRARACQRVVVMVGAGISTPSGIPDFRSPGSGLYSNLQQYDLPYPEAIFELPFFFHNPKPFFTLAKELYPGNYKPNVTHYFLRLLHDKGLLLRLYTQNIDGLERVSGIPASKLVEAHGTFASATCTVCQRPFPGEDIRADVMADRVPRCPVCTGVVKPDIVFFGEPLPQRFLLHVVDFPMADLLLILGTSLEVEPFASLTEAVRSSVPRLLINRDLVGPLAWHPRSRDVAQLGDVVHGVESLVELLGWTEEMRDLVQRETGKLDGPDK Show more |
Homologous gene and protein info.
| Species | Gene ID | Gene Symbol | Name | Tax ID | Other Gene ID | Sources |
|---|---|---|---|---|---|---|
| Macaque | 720737 | SIRT3 | sirtuin 3 | 9544 | Inparanoid, OMA, EggNOG | |
| Mouse | 64384 | Sirt3 | sirtuin 3 | 10090 | MGI:1927665 | Inparanoid, EggNOG |
| Rat | 293615 | Sirt3 | sirtuin 3 | 10116 | RGD:1308374 | Inparanoid, OMA, EggNOG |
| Dog | 475933 | SIRT3 | sirtuin 3 | 9615 | VGNC:46184 | Inparanoid, OMA, EggNOG |
| Horse | 100054908 | SIRT3 | sirtuin 3 | 9796 | VGNC:22988 | Inparanoid, OMA, EggNOG |
| Cow | 614027 | SIRT3 | sirtuin 3 | 9913 | VGNC:34632 | Inparanoid, OMA, EggNOG |
| Pig | 100125971 | SIRT3 | sirtuin 3 | 9823 | Inparanoid, OMA, EggNOG | |
| Opossum | SIRT3 | sirtuin 3 [Source:HGNC Symbol;Acc:HGNC:14931] | 13616 | Inparanoid, EggNOG | ||
| Anole lizard | 100555836 | sirt3 | sirtuin 3 | 28377 | Inparanoid, OMA, EggNOG | |
| Xenopus | SIRT3 | sirtuin 3 [Source:HGNC Symbol;Acc:HGNC:14931] | 8364 | OMA, EggNOG | ||
| Zebrafish | 558775 | sirt3 | sirtuin 3 | 7955 | ZDB-GENE-070112-1762 | Inparanoid, OMA |
| S.cerevisiae | 856092 | HST2 | histone deacetylase HST2 | 4932 | S000005936 | OMA, EggNOG |
Protein Classes
PANTHER Classes
protein / hydrolase / deacetylase / NAD-dependent protein deacetylase sirtuin-3, mitochondrial
protein / hydrolase / chromatin/chromatin-binding protein / NAD-dependent protein deacetylase sirtuin-3, mitochondrial
protein / hydrolase / deacetylase / NAD-dependent protein deacetylase sirtuin-3, mitochondrial
protein / hydrolase / chromatin/chromatin-binding protein / NAD-dependent protein deacetylase sirtuin-3, mitochondrial
DTO Classes
protein / Epigenetic regulator / Eraser / Histone deacetylase / HDAC class III / NAD-dependent protein deacetylase sirtuin-3, mitochondrial
protein / Epigenetic regulator / Eraser / Histone deacetylase / HDAC class III / NAD-dependent protein deacetylase sirtuin-3, mitochondrial
Associated Recombinant Proteins
| Name | Specification and purity | Expression system | Protein label | Activity | View Details |
|---|
Associated Antibodies
| Name | Specifications | Species reactivity | species | Application | View Details |
|---|
Associated Approved Drugs
Associated Active Ligands
Associated Diseases
| Name | Disease Type | Mondoid |
|---|
Pathway
| Data Source | Name | Explore more targets | Explore in Source |
|---|