Protein or Target Summary

NAD-dependent protein deacetylase sirtuin-2

Gene ID	22933
uniprot	Q8IXJ6
Gene Name	SIRT2
Ensernbl ID	ENSP00000249396
Family	Belongs to the sirtuin family. Class I subfamily.
Sequence	MAEPDPSHPLETQAGKVQEAQDSDSDSEGGAAGGEADMDFLRNLFSQTLSLGSQKERLLDELTLEGVARYMQSERCRRVICLVGAGISTSAGIPDFRSPSTGLYDNLEKYHLPYPEAIFEISYFKKHPEPFFALAKELYPGQFKPTICHYFMRLLKDKGLLLRCYTQNIDTLERIAGLEQEDLVEAHGTFYTSHCVSASCRHEYPLSWMKEKIFSEVTPKCEDCQSLVKPDIVFFGESLPARFFSCMQSDFLKVDLLLVMGTSLQVQPFASLISKAPLSTPRLLINKEKAGQSDPFLGMIMGLGGGMDFDSKKAYRDVAWLGECDQGCLALAELLGWKKELEDLVRREHASIDAQSGAGVPNPSTSASPKKSPPPAKDEARTTEREKPQ Show more

Gene and Protein Information

Species	Gene ID	Gene Symbol	Gene Name	Uniprot
HUMAN	22933	SIRT2	NAD-dependent protein deacetylase sirtuin-2	Q8IXJ6
MOUSE		Sirt2	NAD-dependent protein deacetylase	A0A140LHL5
MOUSE		Sirt2	NAD-dependent protein deacetylase	Q3UJK6
MOUSE	64383	Sirt2	NAD-dependent protein deacetylase sirtuin-2	Q8VDQ8
RAT	361532	Sirt2	NAD-dependent protein deacetylase	A0A0G2JWM2
RAT	361532	Sirt2	NAD-dependent protein deacetylase sirtuin-2	Q5RJQ4

Protein Classes

PANTHER Classes
protein / hydrolase / deacetylase / NAD-dependent protein deacetylase sirtuin-2
protein / hydrolase / chromatin/chromatin-binding protein / NAD-dependent protein deacetylase sirtuin-2

DTO Classes
protein / Epigenetic regulator / Eraser / Histone deacetylase / HDAC class III / NAD-dependent protein deacetylase sirtuin-2

Associated Recombinant Proteins

Name	Specification and purity	Expression system	Protein label	Activity	View Details

Associated Antibodies

Name	Specifications	Species reactivity	species	Application	View Details

Associated Approved Drugs

Associated Active Ligands

Associated Diseases

Name	Disease Type	Mondoid

Pathway

Data Source	Name	Explore more targets	Explore in Source

Source: TCRDv6_DataSourcesLicenses.xlsx