SIRT2
| Description | NAD-dependent protein deacetylase sirtuin-2 |
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Gene and Protein Information
| Gene ID | 22933 |
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| Uniprot Accession IDs | A8K3V1 B2RB45 O95889 Q924Y7 Q9P0G8 Q9UNT0 Q9Y6E9 U5TP13 |
| Ensembl ID | ENSP00000249396 |
| Symbol | SIR2L SIR2L2 SIR2 SIR2L SIR2L2 |
| Family | Belongs to the sirtuin family. Class I subfamily. |
| Sequence | MAEPDPSHPLETQAGKVQEAQDSDSDSEGGAAGGEADMDFLRNLFSQTLSLGSQKERLLDELTLEGVARYMQSERCRRVICLVGAGISTSAGIPDFRSPSTGLYDNLEKYHLPYPEAIFEISYFKKHPEPFFALAKELYPGQFKPTICHYFMRLLKDKGLLLRCYTQNIDTLERIAGLEQEDLVEAHGTFYTSHCVSASCRHEYPLSWMKEKIFSEVTPKCEDCQSLVKPDIVFFGESLPARFFSCMQSDFLKVDLLLVMGTSLQVQPFASLISKAPLSTPRLLINKEKAGQSDPFLGMIMGLGGGMDFDSKKAYRDVAWLGECDQGCLALAELLGWKKELEDLVRREHASIDAQSGAGVPNPSTSASPKKSPPPAKDEARTTEREKPQ Show more |
Homologous gene and protein info.
| Species | Gene ID | Gene Symbol | Name | Tax ID | Other Gene ID | Sources |
|---|---|---|---|---|---|---|
| Chimp | 456013 | SIRT2 | sirtuin 2 | 9598 | VGNC:12099 | OMA, EggNOG |
| Macaque | 100425019 | SIRT2 | sirtuin 2 | 9544 | Inparanoid, OMA, EggNOG | |
| Mouse | 64383 | Sirt2 | sirtuin 2 | 10090 | MGI:1927664 | Inparanoid, OMA, EggNOG |
| Rat | 361532 | Sirt2 | sirtuin 2 | 10116 | RGD:621481 | Inparanoid, OMA |
| Dog | 612558 | SIRT2 | sirtuin 2 | 9615 | VGNC:53983 | Inparanoid, OMA, EggNOG |
| Horse | 100146611 | SIRT2 | sirtuin 2 | 9796 | VGNC:22987 | Inparanoid, OMA, EggNOG |
| Cow | 504463 | SIRT2 | sirtuin 2 | 9913 | VGNC:34631 | Inparanoid, OMA, EggNOG |
| Pig | 100125964 | SIRT2 | sirtuin 2 | 9823 | OMA, EggNOG | |
| Anole lizard | 100559366 | sirt2 | sirtuin 2 | 28377 | Inparanoid, OMA | |
| Xenopus | 100489469 | sirt2 | sirtuin 2 | 8364 | XB-GENE-987375 | Inparanoid, OMA |
| Zebrafish | 322309 | sirt2 | sirtuin 2 (silent mating type information regulation 2, homolog) 2 (S. cerevisiae) | 7955 | ZDB-GENE-030131-1028 | Inparanoid, OMA |
| S.cerevisiae | 856092 | HST2 | histone deacetylase HST2 | 4932 | S000005936 | Inparanoid, OMA |
Protein Classes
PANTHER Classes
protein / hydrolase / deacetylase / NAD-dependent protein deacetylase sirtuin-2
protein / hydrolase / chromatin/chromatin-binding protein / NAD-dependent protein deacetylase sirtuin-2
protein / hydrolase / deacetylase / NAD-dependent protein deacetylase sirtuin-2
protein / hydrolase / chromatin/chromatin-binding protein / NAD-dependent protein deacetylase sirtuin-2
DTO Classes
protein / Epigenetic regulator / Eraser / Histone deacetylase / HDAC class III / NAD-dependent protein deacetylase sirtuin-2
protein / Epigenetic regulator / Eraser / Histone deacetylase / HDAC class III / NAD-dependent protein deacetylase sirtuin-2
Associated Recombinant Proteins
| Name | Specification and purity | Expression system | Protein label | Activity | View Details |
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Associated Antibodies
| Name | Specifications | Species reactivity | species | Application | View Details |
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Associated Approved Drugs
Associated Active Ligands
Associated Diseases
| Name | Disease Type | Mondoid |
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Pathway
| Data Source | Name | Explore more targets | Explore in Source |
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