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SIRT6
| Description | NAD-dependent protein deacetylase sirtuin-6 |
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Gene and Protein Information
| Gene ID | 51548 |
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| Uniprot Accession IDs | B2RCD0 O75291 Q6IAF5 Q6PK99 Q8NCD2 Q9BSI5 Q9BWP3 Q9NRC7 Q9UQD1 |
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| Ensembl ID | ENSP00000337332 |
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| Symbol | SIR2L6 SIR2L6 |
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| Family | Belongs to the sirtuin family. Class IV subfamily. |
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| Sequence | MSVNYAAGLSPYADKGKCGLPEIFDPPEELERKVWELARLVWQSSSVVFHTGAGISTASGIPDFRGPHGVWTMEERGLAPKFDTTFESARPTQTHMALVQLERVGLLRFLVSQNVDGLHVRSGFPRDKLAELHGNMFVEECAKCKTQYVRDTVVGTMGLKATGRLCTVAKARGLRACRGELRDTILDWEDSLPDRDLALADEASRNADLSITLGTSLQIRPSGNLPLATKRRGGRLVIVNLQPTKHDRHADLRIHGYVDEVMTRLMKHLGLEIPAWDGPRVLERALPPLPRPPTPKLEPKEESPTRINGSIPAGPKQEPCAQHNGSEPASPKRERPTSPAPHRPPKRVKAKAVPS Show more |
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Homologous gene and protein info.
| Species | Gene ID | Gene Symbol | Name | Tax ID | Other Gene ID | Sources |
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| Chimp | 737026 | SIRT6 | sirtuin 6 | 9598 | VGNC:12101 | OMA, EggNOG |
| Macaque | 714545 | SIRT6 | sirtuin 6 | 9544 | | Inparanoid, OMA, EggNOG |
| Mouse | 50721 | Sirt6 | sirtuin 6 | 10090 | MGI:1354161 | Inparanoid, OMA, EggNOG |
| Rat | 299638 | Sirt6 | sirtuin 6 | 10116 | RGD:1305216 | Inparanoid, OMA, EggNOG |
| Dog | 485045 | SIRT6 | sirtuin 6 | 9615 | VGNC:46187 | Inparanoid, OMA, EggNOG |
| Cow | 535416 | SIRT6 | sirtuin 6 | 9913 | VGNC:34635 | Inparanoid, OMA, EggNOG |
| Pig | 100126274 | SIRT6 | sirtuin 6 | 9823 | | Inparanoid, OMA, EggNOG |
| Opossum | 100022578 | SIRT6 | sirtuin 6 | 13616 | | Inparanoid, OMA, EggNOG |
| Platypus | 100091769 | SIRT6 | sirtuin 6 | 9258 | | Inparanoid, OMA, EggNOG |
| Chicken | 428332 | SIRT6 | sirtuin 6 | 9031 | CGNC:850 | Inparanoid, OMA, EggNOG |
| Xenopus | 394980 | sirt6 | sirtuin 6 | 8364 | XB-GENE-5929105 | Inparanoid, OMA, EggNOG |
| C. elegans | 182284 | sir-2.4 | NAD-dependent protein deacetylase sir-2.4 | 6239 | | Inparanoid, OMA, EggNOG |
| Fruitfly | 41254 | Sirt6 | Sirtuin 6 | 7227 | FBgn0037802 | Inparanoid, OMA, EggNOG |
Associated Recombinant Proteins
| Name | Specification and purity | Expression system | Protein label | Activity | View Details |
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Associated Antibodies
| Name | Specifications | Species reactivity | species | Application | View Details |
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Associated Approved Drugs
Associated Active Ligands
Pathway
| Data Source | Name | Explore more targets | Explore in Source |
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