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Protein or Target Summary

NAD-dependent protein deacetylase sirtuin-6

Gene ID	51548
uniprot	Q8N6T7
Gene Name	SIRT6
Ensernbl ID	ENSP00000337332
Family	Belongs to the sirtuin family. Class IV subfamily.
Sequence	MSVNYAAGLSPYADKGKCGLPEIFDPPEELERKVWELARLVWQSSSVVFHTGAGISTASGIPDFRGPHGVWTMEERGLAPKFDTTFESARPTQTHMALVQLERVGLLRFLVSQNVDGLHVRSGFPRDKLAELHGNMFVEECAKCKTQYVRDTVVGTMGLKATGRLCTVAKARGLRACRGELRDTILDWEDSLPDRDLALADEASRNADLSITLGTSLQIRPSGNLPLATKRRGGRLVIVNLQPTKHDRHADLRIHGYVDEVMTRLMKHLGLEIPAWDGPRVLERALPPLPRPPTPKLEPKEESPTRINGSIPAGPKQEPCAQHNGSEPASPKRERPTSPAPHRPPKRVKAKAVPS Show more

Gene and Protein Information

Species	Gene ID	Gene Symbol	Gene Name	Uniprot
HUMAN	51548	SIRT6	NAD-dependent protein deacetylase sirtuin-6	Q8N6T7
MOUSE		Sirt6	NAD-dependent protein deacetylase sirtuin-6	D3YY89
MOUSE	50721	Sirt6	NAD-dependent protein deacetylase sirtuin-6	Q3UKP1
MOUSE	50721	Sirt6	NAD-dependent protein deacetylase sirtuin-6	P59941
RAT	299638	Sirt6	Sirtuin 6	Q4FZY2

Protein Classes

DTO Classes
protein / Epigenetic regulator / Eraser / Histone deacetylase / HDAC class III / NAD-dependent protein deacetylase sirtuin-6

Associated Recombinant Proteins

Name	Specification and purity	Expression system	Protein label	Activity	View Details

Associated Antibodies

Name	Specifications	Species reactivity	species	Application	View Details

Associated Approved Drugs

Associated Active Ligands

Associated Diseases

Name	Disease Type	Mondoid

Pathway

Data Source	Name	Explore more targets	Explore in Source

Source: TCRDv6_DataSourcesLicenses.xlsx