SOS1

DescriptionSon of sevenless homolog 1

Gene and Protein Information

Gene ID6654
Uniprot Accession IDs A8K2G3 B4DXG2 SOS-1
Ensembl ID ENSP00000387784
Symbol GF1 HGF NS4 GGF1 GINGF SOS-1
Sequence
MQAQQLPYEFFSEENAPKWRGLLVPALKKVQGQVHPTLESNDDALQYVEELILQLLNMLCQAQPRSASDVEERVQKSFPHPIDKWAIADAQSAIEKRKRRNPLSLPVEKIHPLLKEVLGYKIDHQVSVYIVAVLEYISADILKLVGNYVRNIRHYEITKQDIKVAMCADKVLMDMFHQDVEDINILSLTDEEPSTSGEQTYYDLVKAFMAEIRQYIRELNLIIKVFREPFVSNSKLFSANDVENIFSRIVDIHELSVKLLGHIEDTVEMTDEGSPHPLVGSCFEDLAEELAFDPYESYARDILRPGFHDRFLSQLSKPGAALYLQSIGEGFKEAVQYVLPRLLLAPVYHCLHYFELLKQLEEKSEDQEDKECLKQAITALLNVQSGMEKICSKSLAKRRLSESACRFYSQQMKGKQLAIKKMNEIQKNIDGWEGKDIGQCCNEFIMEGTLTRVGAKHERHIFLFDGLMICCKSNHGQPRLPGASNAEYRLKEKFFMRKVQINDKDDTNEYKHAFEIILKDENSVIFSAKSAEEKNNWMAALISLQYRSTLERMLDVTMLQEEKEEQMRLPSADVYRFAEPDSEENIIFEENMQPKAGIPIIKAGTVIKLIERLTYHMYADPNFVRTFLTTYRSFCKPQELLSLIIERFEIPEPEPTEADRIAIENGDQPLSAELKRFRKEYIQPVQLRVLNVCRHWVEHHFYDFERDAYLLQRMEEFIGTVRGKAMKKWVESITKIIQRKKIARDNGPGHNITFQSSPPTVEWHISRPGHIETFDLLTLHPIEIARQLTLLESDLYRAVQPSELVGSVWTKEDKEINSPNLLKMIRHTTNLTLWFEKCIVETENLEERVAVVSRIIEILQVFQELNNFNGVLEVVSAMNSSPVYRLDHTFEQIPSRQKKILEEAHELSEDHYKKYLAKLRSINPPCVPFFGIYLTNILKTEEGNPEVLKRHGKELINFSKRRKVAEITGEIQQYQNQPYCLRVESDIKRFFENLNPMGNSMEKEFTDYLFNKSLEIEPRNPKPLPRFPKKYSYPLKSPGVRPSNPRPGTMRHPTPLQQEPRKISYSRIPESETESTASAPNSPRTPLTPPPASGASSTTDVCSVFDSDHSSPFHSSNDTVFIQVTLPHGPRSASVSSISLTKGTDEVPVPPPVPPRRRPESAPAESSPSKIMSKHLDSPPAIPPRQPTSKAYSPRYSISDRTSISDPPESPPLLPPREPVRTPDVFSSSPLHLQPPPLGKKSDHGNAFFPNSPSPFTPPPPQTPSPHGTRRHLPSPPLTQEVDLHSIAGPPVPPRQSTSQHIPKLPPKTYKREHTHPSMHRDGPPLLENAHSS
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Homologous gene and protein info.
SpeciesGene IDGene SymbolNameTax IDOther Gene IDSources
Chimp459171SOS1SOS Ras/Rac guanine nucleotide exchange factor 19598VGNC:6658OMA, EggNOG
Macaque713777SOS1SOS Ras/Rac guanine nucleotide exchange factor 19544Inparanoid, OMA, EggNOG
Mouse20662Sos1SOS Ras/Rac guanine nucleotide exchange factor 110090MGI:98354Inparanoid, OMA, EggNOG
Rat313845Sos1SOS Ras/Rac guanine nucleotide exchange factor 110116RGD:1310949Inparanoid, OMA, EggNOG
Dog483042SOS1SOS Ras/Rac guanine nucleotide exchange factor 19615VGNC:46665Inparanoid, OMA, EggNOG
Horse100053889SOS1SOS Ras/Rac guanine nucleotide exchange factor 19796VGNC:23454Inparanoid, OMA, EggNOG
Cow537682SOS1SOS Ras/Rac guanine nucleotide exchange factor 19913VGNC:35134Inparanoid, OMA, EggNOG
PigSOS1SOS Ras/Rac guanine nucleotide exchange factor 1 [Source:HGNC Symbol;Acc:HGNC:11187]9823OMA, EggNOG
Opossum100618058SOS1SOS Ras/Rac guanine nucleotide exchange factor 113616Inparanoid, EggNOG
Platypus100078989SOS1SOS Ras/Rac guanine nucleotide exchange factor 19258Inparanoid, OMA, EggNOG
Anole lizard100559237sos1SOS Ras/Rac guanine nucleotide exchange factor 128377Inparanoid, OMA
Xenopus100489960sos1SOS Ras/Rac guanine nucleotide exchange factor 18364XB-GENE-1011399Inparanoid, OMA
Fruitfly34790SosSon of sevenless7227FBgn0001965Inparanoid, OMA

Protein Classes

PANTHER Classes
protein    /    enzyme modulator    /    guanyl-nucleotide exchange factor    /    Son of sevenless homolog 1
DTO Classes
protein    /    Enzyme modulator    /    G-protein modulator    /    Guanyl-nucleotide exchange factor    /    Son of sevenless homolog 1

Associated Recombinant Proteins

NameSpecification and purityExpression systemProtein labelActivityView Details

Associated Antibodies

NameSpecificationsSpecies reactivityspeciesApplicationView Details

Associated Approved Drugs

    Associated Active Ligands

      Associated Diseases

      NameDisease TypeMondoid

      Pathway

      Data SourceNameExplore more targetsExplore in Source