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ERBB4
| Description | Receptor tyrosine-protein kinase erbB-4 |
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Gene and Protein Information
| Gene ID | 2066 |
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| Uniprot Accession IDs | B7ZLD7 B7ZLE2 B7ZLE3 Q2M1W1 Q59EW4 |
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| Ensembl ID | ENSP00000342235 |
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| Symbol | HER4 HER4 ALS19 p180erbB4 |
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| Family | Belongs to the protein kinase superfamily. Tyr protein kinase family. EGF receptor subfamily. |
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| Sequence | MKPATGLWVWVSLLVAAGTVQPSDSQSVCAGTENKLSSLSDLEQQYRALRKYYENCEVVMGNLEITSIEHNRDLSFLRSVREVTGYVLVALNQFRYLPLENLRIIRGTKLYEDRYALAIFLNYRKDGNFGLQELGLKNLTEILNGGVYVDQNKFLCYADTIHWQDIVRNPWPSNLTLVSTNGSSGCGRCHKSCTGRCWGPTENHCQTLTRTVCAEQCDGRCYGPYVSDCCHRECAGGCSGPKDTDCFACMNFNDSGACVTQCPQTFVYNPTTFQLEHNFNAKYTYGAFCVKKCPHNFVVDSSSCVRACPSSKMEVEENGIKMCKPCTDICPKACDGIGTGSLMSAQTVDSSNIDKFINCTKINGNLIFLVTGIHGDPYNAIEAIDPEKLNVFRTVREITGFLNIQSWPPNMTDFSVFSNLVTIGGRVLYSGLSLLILKQQGITSLQFQSLKEISAGNIYITDNSNLCYYHTINWTTLFSTINQRIVIRDNRKAENCTAEGMVCNHLCSSDGCWGPGPDQCLSCRRFSRGRICIESCNLYDGEFREFENGSICVECDPQCEKMEDGLLTCHGPGPDNCTKCSHFKDGPNCVEKCPDGLQGANSFIFKYADPDRECHPCHPNCTQGCNGPTSHDCIYYPWTGHSTLPQHARTPLIAAGVIGGLFILVIVGLTFAVYVRRKSIKKKRALRRFLETELVEPLTPSGTAPNQAQLRILKETELKRVKVLGSGAFGTVYKGIWVPEGETVKIPVAIKILNETTGPKANVEFMDEALIMASMDHPHLVRLLGVCLSPTIQLVTQLMPHGCLLEYVHEHKDNIGSQLLLNWCVQIAKGMMYLEERRLVHRDLAARNVLVKSPNHVKITDFGLARLLEGDEKEYNADGGKMPIKWMALECIHYRKFTHQSDVWSYGVTIWELMTFGGKPYDGIPTREIPDLLEKGERLPQPPICTIDVYMVMVKCWMIDADSRPKFKELAAEFSRMARDPQRYLVIQGDDRMKLPSPNDSKFFQNLLDEEDLEDMMDAEEYLVPQAFNIPPPIYTSRARIDSNRSEIGHSPPPAYTPMSGNQFVYRDGGFAAEQGVSVPYRAPTSTIPEAPVAQGATAEIFDDSCCNGTLRKPVAPHVQEDSSTQRYSADPTVFAPERSPRGELDEEGYMTPMRDKPKQEYLNPVEENPFVSRRKNGDLQALDNPEYHNASNGPPKAEDEYVNEPLYLNTFANTLGKAEYLKNNILSMPEKAKKAFDNPDYWNHSLPPRSTLQHPDYLQEYSTKYFYKQNGRIRPIVAENPEYLSEFSLKPGTVLPPPPYRHRNTVV Show more |
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Homologous gene and protein info.
| Species | Gene ID | Gene Symbol | Name | Tax ID | Other Gene ID | Sources |
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| Chimp | 459919 | ERBB4 | erb-b2 receptor tyrosine kinase 4 | 9598 | VGNC:372 | OMA, EggNOG |
| Macaque | 693341 | ERBB4 | erb-b2 receptor tyrosine kinase 4 | 9544 | | OMA, EggNOG |
| Mouse | 13869 | Erbb4 | erb-b2 receptor tyrosine kinase 4 | 10090 | MGI:104771 | Inparanoid, OMA, EggNOG |
| Rat | 59323 | Erbb4 | erb-b2 receptor tyrosine kinase 4 | 10116 | RGD:620486 | Inparanoid, OMA, EggNOG |
| Dog | 488508 | ERBB4 | erb-b2 receptor tyrosine kinase 4 | 9615 | VGNC:40437 | Inparanoid, OMA, EggNOG |
| Horse | 100050182 | ERBB4 | erb-b2 receptor tyrosine kinase 4 | 9796 | VGNC:17651 | Inparanoid, OMA, EggNOG |
| Opossum | 100014865 | ERBB4 | erb-b2 receptor tyrosine kinase 4 | 13616 | | Inparanoid, OMA, EggNOG |
| Platypus | 100077353 | ERBB4 | erb-b2 receptor tyrosine kinase 4 | 9258 | | Inparanoid, OMA, EggNOG |
| Chicken | 395671 | ERBB4 | erb-b2 receptor tyrosine kinase 4 | 9031 | CGNC:49428 | Inparanoid, OMA |
| Anole lizard | 100558986 | erbb4 | erb-b2 receptor tyrosine kinase 4 | 28377 | | Inparanoid, OMA |
| Xenopus | 100493234 | erbb4 | erb-b2 receptor tyrosine kinase 4 | 8364 | XB-GENE-877077 | Inparanoid, OMA |
Associated Recombinant Proteins
| Name | Specification and purity | Expression system | Protein label | Activity | View Details |
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Associated Antibodies
| Name | Specifications | Species reactivity | species | Application | View Details |
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Associated Approved Drugs
Associated Active Ligands
Pathway
| Data Source | Name | Explore more targets | Explore in Source |
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