SLC9A3

DescriptionSodium/hydrogen exchanger 3

Gene and Protein Information

Gene ID6550
Uniprot Accession IDs B7ZKR2 E9PF67 Q3MIW3
Ensembl ID ENSP00000264938
Symbol NHE3 NHE3 DIAR8 NHE-3
FamilyBelongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.
Sequence
MWGLGARGPDRGLLLALALGGLARAGGVEVEPGGAHGESGGFQVVTFEWAHVQDPYVIALWILVASLAKIGFHLSHKVTSVVPESALLIVLGLVLGGIVWAADHIASFTLTPTVFFFYLLPPIVLDAGYFMPNRLFFGNLGTILLYAVVGTVWNAATTGLSLYGVFLSGLMGDLQIGLLDFLLFGSLMAAVDPVAVLAVFEEVHVNEVLFIIVFGESLLNDAVTVVLYNVFESFVALGGDNVTGVDCVKGIVSFFVVSLGGTLVGVVFAFLLSLVTRFTKHVRIIEPGFVFIISYLSYLTSEMLSLSAILAITFCGICCQKYVKANISEQSATTVRYTMKMLASSAETIIFMFLGISAVNPFIWTWNTAFVLLTLVFISVYRAIGVVLQTWLLNRYRMVQLEPIDQVVLSYGGLRGAVAFALVVLLDGDKVKEKNLFVSTTIIVVFFTVIFQGLTIKPLVQWLKVKRSEHREPRLNEKLHGRAFDHILSAIEDISGQIGHNYLRDKWSHFDRKFLSRVLMRRSAQKSRDRILNVFHELNLKDAISYVAEGERRGSLAFIRSPSTDNVVNVDFTPRSSTVEASVSYLLRENVSAVCLDMQSLEQRRRSIRDAEDMVTHHTLQQYLYKPRQEYKHLYSRHELTPTEDEKQDREIFHRTMRKRLESFKSTKLGLNQNKKAAKLYKRERAQKRRNSSIPNGKLPMESPAQNFTIKEKDLELSDTEEPPNYDEEMSGGIEFLASVTKDTASDSPAGIDNPVFSPDEALDRSLLARLPPWLSPGETVVPSQRARTQIPYSPGTFCRLMPFRLSSKSVDSFLQADGPEERPPAALPESTHM
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Homologous gene and protein info.
SpeciesGene IDGene SymbolNameTax IDOther Gene IDSources
Chimp741885SLC9A3solute carrier family 9 member A39598VGNC:13592Inparanoid, OMA, EggNOG
Macaque708641SLC9A3solute carrier family 9 member A39544OMA, EggNOG
Mouse105243Slc9a3solute carrier family 9 (sodium/hydrogen exchanger), member 310090MGI:105064Inparanoid, OMA, EggNOG
Rat24784Slc9a3solute carrier family 9 member A310116RGD:3720Inparanoid, OMA, EggNOG
Dog488073SLC9A3solute carrier family 9 member A39615VGNC:53464Inparanoid, OMA
Horse100034109SLC9A3solute carrier family 9 member A39796VGNC:23278Inparanoid, OMA, EggNOG
Cow407112SLC9A3solute carrier family 9 member A39913VGNC:34940Inparanoid, OMA
Opossum100011473SLC9A3solute carrier family 9 member A313616Inparanoid, OMA
Anole lizard100567923slc9a3solute carrier family 9 member A328377Inparanoid, OMA, EggNOG
Xenopusslc9a3solute carrier family 9 member A3 [Source:Xenbase;Acc:XB-GENE-6468280]8364OMA, EggNOG
Zebrafish568258slc9a3.1solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3, tandem duplicate 17955ZDB-GENE-060503-545OMA, EggNOG

Protein Classes

DTO Classes
protein    /    Transporter    /    SLC superfamily of solute carriers    /    SLC9 family of sodium/hydrogen exchangers    /    Sodium/hydrogen exchanger 3

Associated Recombinant Proteins

NameSpecification and purityExpression systemProtein labelActivityView Details

Associated Antibodies

NameSpecificationsSpecies reactivityspeciesApplicationView Details

Associated Approved Drugs

    Associated Active Ligands

      Associated Diseases

      NameDisease TypeMondoid

      Pathway

      Data SourceNameExplore more targetsExplore in Source