SMO

Description	Smoothened homolog

Gene and Protein Information

Gene ID	6608
Uniprot Accession IDs	A4D1K5 SMO
Ensembl ID	ENSP00000249373
Symbol	SMOH Gx CRJS SMOH FZD11
Family	Belongs to the G-protein coupled receptor Fz/Smo family.
Sequence	MAAARPARGPELPLLGLLLLLLLGDPGRGAASSGNATGPGPRSAGGSARRSAAVTGPPPPLSHCGRAAPCEPLRYNVCLGSVLPYGATSTLLAGDSDSQEEAHGKLVLWSGLRNAPRCWAVIQPLLCAVYMPKCENDRVELPSRTLCQATRGPCAIVERERGWPDFLRCTPDRFPEGCTNEVQNIKFNSSGQCEVPLVRTDNPKSWYEDVEGCGIQCQNPLFTEAEHQDMHSYIAAFGAVTGLCTLFTLATFVADWRNSNRYPAVILFYVNACFFVGSIGWLAQFMDGARREIVCRADGTMRLGEPTSNETLSCVIIFVIVYYALMAGVVWFVVLTYAWHTSFKALGTTYQPLSGKTSYFHLLTWSLPFVLTVAILAVAQVDGDSVSGICFVGYKNYRYRAGFVLAPIGLVLIVGGYFLIRGVMTLFSIKSNHPGLLSEKAASKINETMLRLGIFGFLAFGFVLITFSCHFYDFFNQAEWERSFRDYVLCQANVTIGLPTKQPIPDCEIKNRPSLLVEKINLFAMFGTGIAMSTWVWTKATLLIWRRTWCRLTGQSDDEPKRIKKSKMIAKAFSKRHELLQNPGQELSFSMHTVSHDGPVAGLAFDLNEPSADVSSAWAQHVTKMVARRGAILPQDISVTPVATPVPPEEQANLWLVEAEISPELQKRLGRKKKRRKRKKEVCPLAPPPELHPPAPAPSTIPRLPQLPRQKCLVAAGAWGAGDSCRQGAWTLVSNPFCPEPSPPQDPFLPSAPAPVAWAHGRRQGLGPIHSRTNLMDTELMDADSDF Show more

Homologous gene and protein info.

Species	Gene ID	Gene Symbol	Name	Tax ID	Other Gene ID	Sources
Chimp	463718	SMO	smoothened, frizzled class receptor	9598	VGNC:4508	OMA, EggNOG
Macaque	701334	SMO	smoothened, frizzled class receptor	9544		Inparanoid, OMA, EggNOG
Mouse	319757	Smo	smoothened, frizzled class receptor	10090	MGI:108075	Inparanoid, OMA, EggNOG
Rat	25273	Smo	smoothened, frizzled class receptor	10116	RGD:3726	Inparanoid, OMA, EggNOG
Dog	482262	SMO	smoothened, frizzled class receptor	9615	VGNC:46565	Inparanoid, OMA, EggNOG
Horse	100033990	SMO	smoothened, frizzled class receptor	9796	VGNC:23350	Inparanoid, OMA, EggNOG
Cow	539308	SMO	smoothened, frizzled class receptor	9913	VGNC:35025	Inparanoid, OMA, EggNOG
Pig	100515110	SMO	smoothened, frizzled class receptor	9823		Inparanoid, OMA, EggNOG
Opossum	100015195	SMO	smoothened, frizzled class receptor	13616		Inparanoid, OMA, EggNOG
Platypus	100078770	SMO	smoothened, frizzled class receptor	9258		Inparanoid, OMA, EggNOG
Anole lizard	100553408	smo	smoothened, frizzled class receptor	28377		Inparanoid, OMA, EggNOG
Xenopus	100491644	smo	smoothened, frizzled class receptor	8364	XB-GENE-487420	Inparanoid, OMA, EggNOG
Zebrafish	30225	smo	smoothened, frizzled class receptor	7955	ZDB-GENE-980526-89	Inparanoid, OMA, EggNOG
Fruitfly	33196	smo	smoothened	7227	FBgn0003444	Inparanoid, EggNOG

Protein Classes

PANTHER Classes
protein    /    receptor    /    protease inhibitor    /    Smoothened homolog
protein    /    receptor    /    signaling molecule    /    Smoothened homolog
protein    /    receptor    /    G-protein coupled receptor    /    Smoothened homolog

DTO Classes
protein / G-protein coupled receptor / Class F frizzled-type / Smoothened homolog

Associated Recombinant Proteins

Name	Specification and purity	Expression system	Protein label	Activity	View Details

Associated Antibodies

Name	Specifications	Species reactivity	species	Application	View Details

Associated Approved Drugs

Associated Active Ligands

Associated Diseases

Name	Disease Type	Mondoid

Pathway

Data Source	Name	Explore more targets	Explore in Source

🔙[Back to Target (Human)]

SMO