SF3B3

DescriptionSplicing factor 3B subunit 3

Gene and Protein Information

Gene ID23450
Uniprot Accession IDs Q6NTI8 Q96GC0 Q9BPY2 Q9UFX7 Q9UJ29
Ensembl ID ENSP00000305790
Symbol KIAA0017 SAP130 RSE1 SAP130 SF3b130 STAF130
FamilyBelongs to the RSE1 family.
Sequence
MFLYNLTLQRATGISFAIHGNFSGTKQQEIVVSRGKILELLRPDPNTGKVHTLLTVEVFGVIRSLMAFRLTGGTKDYIVVGSDSGRIVILEYQPSKNMFEKIHQETFGKSGCRRIVPGQFLAVDPKGRAVMISAIEKQKLVYILNRDAAARLTISSPLEAHKANTLVYHVVGVDVGFENPMFACLEMDYEEADNDPTGEAAANTQQTLTFYELDLGLNHVVRKYSEPLEEHGNFLITVPGGSDGPSGVLICSENYITYKNFGDQPDIRCPIPRRRNDLDDPERGMIFVCSATHKTKSMFFFLAQTEQGDIFKITLETDEDMVTEIRLKYFDTVPVAAAMCVLKTGFLFVASEFGNHYLYQIAHLGDDDEEPEFSSAMPLEEGDTFFFQPRPLKNLVLVDELDSLSPILFCQIADLANEDTPQLYVACGRGPRSSLRVLRHGLEVSEMAVSELPGNPNAVWTVRRHIEDEFDAYIIVSFVNATLVLSIGETVEEVTDSGFLGTTPTLSCSLLGDDALVQVYPDGIRHIRADKRVNEWKTPGKKTIVKCAVNQRQVVIALTGGELVYFEMDPSGQLNEYTERKEMSADVVCMSLANVPPGEQRSRFLAVGLVDNTVRIISLDPSDCLQPLSMQALPAQPESLCIVEMGGTEKQDELGERGSIGFLYLNIGLQNGVLLRTVLDPVTGDLSDTRTRYLGSRPVKLFRVRMQGQEAVLAMSSRSWLSYSYQSRFHLTPLSYETLEFASGFASEQCPEGIVAISTNTLRILALEKLGAVFNQVAFPLQYTPRKFVIHPESNNLIIIETDHNAYTEATKAQRKQQMAEEMVEAAGEDERELAAEMAAAFLNENLPESIFGAPKAGNGQWASVIRVMNPIQGNTLDLVQLEQNEAAFSVAVCRFSNTGEDWYVLVGVAKDLILNPRSVAGGFVYTYKLVNNGEKLEFLHKTPVEEVPAAIAPFQGRVLIGVGKLLRVYDLGKKKLLRKCENKHIANYISGIQTIGHRVIVSDVQESFIWVRYKRNENQLIIFADDTYPRWVTTASLLDYDTVAGADKFGNICVVRLPPNTNDEVDEDPTGNKALWDRGLLNGASQKAEVIMNYHVGETVLSLQKTTLIPGGSESLVYTTLSGGIGILVPFTSHEDHDFFQHVEMHLRSEHPPLCGRDHLSFRSYYFPVKNVIDGDLCEQFNSMEPNKQKNVSEELDRTPPEVSKKLEDIRTRYAF
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Homologous gene and protein info.
SpeciesGene IDGene SymbolNameTax IDOther Gene IDSources
Chimp454216SF3B3splicing factor 3b subunit 39598VGNC:5918OMA, EggNOG
Macaque708939SF3B3splicing factor 3b subunit 39544OMA, EggNOG
Mouse101943Sf3b3splicing factor 3b, subunit 310090MGI:1289341Inparanoid, OMA, EggNOG
Rat292019Sf3b3splicing factor 3b, subunit 310116RGD:1311636Inparanoid, OMA, EggNOG
Dog479659SF3B3splicing factor 3b subunit 39615VGNC:46071Inparanoid, OMA, EggNOG
Horse100054753SF3B3splicing factor 3b subunit 39796VGNC:22890Inparanoid, OMA, EggNOG
Cow504962SF3B3splicing factor 3b subunit 39913VGNC:34511Inparanoid, OMA, EggNOG
Opossum100024525SF3B3splicing factor 3b subunit 313616Inparanoid, EggNOG
Platypus100074472SF3B3splicing factor 3b subunit 39258Inparanoid, OMA, EggNOG
Chicken415680SF3B3splicing factor 3b subunit 39031CGNC:1817Inparanoid, OMA, EggNOG
Anole lizard100560403sf3b3splicing factor 3b subunit 328377Inparanoid, OMA, EggNOG
Xenopus100101755sf3b3splicing factor 3b subunit 38364XB-GENE-921994Inparanoid, OMA, EggNOG
Zebrafish406824sf3b3splicing factor 3b, subunit 37955ZDB-GENE-040426-2901Inparanoid, OMA
C. elegans172406teg-4Tumorous Enhancer of Glp-1(gf)6239Inparanoid, OMA, EggNOG
S.cerevisiae854956RSE1U2 snRNP complex subunit RSE14932S000004513Inparanoid, OMA, EggNOG

Protein Classes

PANTHER Classes
protein    /    nucleic acid binding    /    damaged DNA-binding protein    /    Splicing factor 3B subunit 3
protein    /    nucleic acid binding    /    mRNA polyadenylation factor    /    Splicing factor 3B subunit 3
protein    /    nucleic acid binding    /    mRNA splicing factor    /    Splicing factor 3B subunit 3
DTO Classes
protein    /    Nucleic acid binding    /    RNA binding protein    /    mRNA processing factor    /    mRNA splicing factor    /    Splicing factor 3B subunit 3

Associated Recombinant Proteins

NameSpecification and purityExpression systemProtein labelActivityView Details

Associated Antibodies

NameSpecificationsSpecies reactivityspeciesApplicationView Details

Associated Approved Drugs

    Associated Active Ligands

      Associated Diseases

      NameDisease TypeMondoid

      Pathway

      Data SourceNameExplore more targetsExplore in Source