| Description | Sodium/glucose cotransporter 2 |
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Gene and Protein Information
| Gene ID | 6524 |
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| Uniprot Accession IDs | A2RRD2 Na(+)/glucose cotransporter 2 |
| Ensembl ID | ENSP00000327943 |
| Symbol | SGLT2 SGLT2 |
| Family | Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. |
| Sequence | MEEHTEAGSAPEMGAQKALIDNPADILVIAAYFLLVIGVGLWSMCRTNRGTVGGYFLAGRSMVWWPVGASLFASNIGSGHFVGLAGTGAASGLAVAGFEWNALFVVLLLGWLFAPVYLTAGVITMPQYLRKRFGGRRIRLYLSVLSLFLYIFTKISVDMFSGAVFIQQALGWNIYASVIALLGITMIYTVTGGLAALMYTDTVQTFVILGGACILMGYAFHEVGGYSGLFDKYLGAATSLTVSEDPAVGNISSFCYRPRPDSYHLLRHPVTGDLPWPALLLGLTIVSGWYWCSDQVIVQRCLAGKSLTHIKAGCILCGYLKLTPMFLMVMPGMISRILYPDEVACVVPEVCRRVCGTEVGCSNIAYPRLVVKLMPNGLRGLMLAVMLAALMSSLASIFNSSSTLFTMDIYTRLRPRAGDRELLLVGRLWVVFIVVVSVAWLPVVQAAQGGQLFDYIQAVSSYLAPPVSAVFVLALFVPRVNEQGAFWGLIGGLLMGLARLIPEFSFGSGSCVQPSACPAFLCGVHYLYFAIVLFFCSGLLTLTVSLCTAPIPRKHLHRLVFSLRHSKEEREDLDADEQQGSSLPVQNGCPESAMEMNEPQAPAPSLFRQCLLWFCGMSRGGVGSPPPLTQEEAAAAARRLEDISEDPSWARVVNLNALLMMAVAVFLWGFYA Show more |
Homologous gene and protein info.
| Species | Gene ID | Gene Symbol | Name | Tax ID | Other Gene ID | Sources |
|---|---|---|---|---|---|---|
| Chimp | 467963 | SLC5A2 | solute carrier family 5 member 2 | 9598 | VGNC:9016 | OMA, EggNOG |
| Macaque | 714228 | SLC5A2 | solute carrier family 5 member 2 | 9544 | Inparanoid, OMA, EggNOG | |
| Mouse | 246787 | Slc5a2 | solute carrier family 5 (sodium/glucose cotransporter), member 2 | 10090 | MGI:2181411 | Inparanoid, OMA |
| Rat | 64522 | Slc5a2 | solute carrier family 5 member 2 | 10116 | RGD:620217 | Inparanoid, OMA, EggNOG |
| Dog | 492301 | SLC5A2 | solute carrier family 5 member 2 | 9615 | VGNC:46446 | Inparanoid, OMA |
| Horse | 100064641 | SLC5A2 | solute carrier family 5 member 2 | 9796 | VGNC:23246 | Inparanoid, OMA |
| Cow | 399680 | SLC5A2 | solute carrier family 5 member 2 | 9913 | VGNC:34906 | Inparanoid, OMA |
| Pig | 100286743 | SLC5A2 | solute carrier family 5 member 2 | 9823 | Inparanoid, OMA, EggNOG | |
| Opossum | 100016631 | SLC5A2 | solute carrier family 5 member 2 | 13616 | Inparanoid, OMA | |
| Anole lizard | 100557391 | slc5a2 | solute carrier family 5 member 2 | 28377 | Inparanoid, OMA | |
| Zebrafish | 405862 | slc5a2 | solute carrier family 5 (sodium/glucose cotransporter), member 2 | 7955 | ZDB-GENE-040426-2498 | Inparanoid, OMA |
Protein Classes
PANTHER Classes
protein / transporter / carbohydrate transporter / Sodium/glucose cotransporter 2
protein / transporter / cation transporter / Sodium/glucose cotransporter 2
protein / transporter / carbohydrate transporter / Sodium/glucose cotransporter 2
protein / transporter / cation transporter / Sodium/glucose cotransporter 2
DTO Classes
protein / Transporter / SLC superfamily of solute carriers / SLC5 family of sodium-dependent glucose transporters / Hexose transporter family / Sodium/glucose cotransporter 2
protein / Transporter / SLC superfamily of solute carriers / SLC5 family of sodium-dependent glucose transporters / Hexose transporter family / Sodium/glucose cotransporter 2
Associated Recombinant Proteins
| Name | Specification and purity | Expression system | Protein label | Activity | View Details |
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Associated Antibodies
| Name | Specifications | Species reactivity | species | Application | View Details |
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Associated Approved Drugs
Associated Active Ligands
Associated Diseases
| Name | Disease Type | Mondoid |
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Pathway
| Data Source | Name | Explore more targets | Explore in Source |
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