| Description | Sodium/iodide cotransporter |
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Gene and Protein Information
| Gene ID | 6528 |
|---|---|
| Uniprot Accession IDs | O43702 Q2M335 Q9NYB6 Na(+)/I(-) cotransporter |
| Ensembl ID | ENSP00000222248 |
| Symbol | NIS NIS TDH1 |
| Family | Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. |
| Sequence | MEAVETGERPTFGAWDYGVFALMLLVSTGIGLWVGLARGGQRSAEDFFTGGRRLAALPVGLSLSASFMSAVQVLGVPSEAYRYGLKFLWMCLGQLLNSVLTALLFMPVFYRLGLTSTYEYLEMRFSRAVRLCGTLQYIVATMLYTGIVIYAPALILNQVTGLDIWASLLSTGIICTFYTAVGGMKAVVWTDVFQVVVMLSGFWVVLARGVMLVGGPRQVLTLAQNHSRINLMDFNPDPRSRYTFWTFVVGGTLVWLSMYGVNQAQVQRYVACRTEKQAKLALLINQVGLFLIVSSAACCGIVMFVFYTDCDPLLLGRISAPDQYMPLLVLDIFEDLPGVPGLFLACAYSGTLSTASTSINAMAAVTVEDLIKPRLRSLAPRKLVIISKGLSLIYGSACLTVAALSSLLGGGVLQGSFTVMGVISGPLLGAFILGMFLPACNTPGVLAGLGAGLALSLWVALGATLYPPSEQTMRVLPSSAARCVALSVNASGLLDPALLPANDSSRAPSSGMDASRPALADSFYAISYLYYGALGTLTTVLCGALISCLTGPTKRSTLAPGLLWWDLARQTASVAPKEEVAILDDNLVKGPEELPTGNKKPPGFLPTNEDRLFFLGQKELEGAGSWTPCVGHDGGRDQQETNL Show more |
Homologous gene and protein info.
| Species | Gene ID | Gene Symbol | Name | Tax ID | Other Gene ID | Sources |
|---|---|---|---|---|---|---|
| Chimp | 468767 | SLC5A5 | solute carrier family 5 member 5 | 9598 | VGNC:7781 | OMA, EggNOG |
| Macaque | 720060 | SLC5A5 | solute carrier family 5 member 5 | 9544 | OMA, EggNOG | |
| Mouse | 114479 | Slc5a5 | solute carrier family 5 (sodium iodide symporter), member 5 | 10090 | MGI:2149330 | Inparanoid, OMA, EggNOG |
| Rat | 114613 | Slc5a5 | solute carrier family 5 member 5 | 10116 | RGD:69267 | Inparanoid, OMA, EggNOG |
| Dog | 484830 | SLC5A5 | solute carrier family 5 member 5 | 9615 | VGNC:46448 | Inparanoid, OMA, EggNOG |
| Horse | SLC5A5 | solute carrier family 5 member 5 [Source:HGNC Symbol;Acc:HGNC:11040] | 9796 | OMA, EggNOG | ||
| Cow | 505310 | SLC5A5 | solute carrier family 5 member 5 | 9913 | VGNC:34908 | Inparanoid, OMA, EggNOG |
| Pig | 399542 | SLC5A5 | solute carrier family 5 member 5 | 9823 | Inparanoid, OMA, EggNOG | |
| Xenopus | 100144711 | slc5a5 | solute carrier family 5 member 5 | 8364 | XB-GENE-486472 | Inparanoid, OMA, EggNOG |
| Zebrafish | 561445 | slc5a5 | solute carrier family 5 (sodium/iodide cotransporter), member 5 | 7955 | ZDB-GENE-060503-585 | Inparanoid, OMA |
Protein Classes
PANTHER Classes
protein / transporter / carbohydrate transporter / Sodium/iodide cotransporter
protein / transporter / cation transporter / Sodium/iodide cotransporter
protein / transporter / carbohydrate transporter / Sodium/iodide cotransporter
protein / transporter / cation transporter / Sodium/iodide cotransporter
DTO Classes
protein / Transporter / SLC superfamily of solute carriers / SLC5 family of sodium-dependent glucose transporters / Sodium iodide symporter, sodium-dependent multivitamin transporter and sodium-coupled monocarboxylate transporters / Sodium/iodide cotransporter
protein / Transporter / SLC superfamily of solute carriers / SLC5 family of sodium-dependent glucose transporters / Sodium iodide symporter, sodium-dependent multivitamin transporter and sodium-coupled monocarboxylate transporters / Sodium/iodide cotransporter
Associated Recombinant Proteins
| Name | Specification and purity | Expression system | Protein label | Activity | View Details |
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Associated Antibodies
| Name | Specifications | Species reactivity | species | Application | View Details |
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Associated Approved Drugs
Associated Active Ligands
Associated Diseases
| Name | Disease Type | Mondoid |
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Pathway
| Data Source | Name | Explore more targets | Explore in Source |
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