SLC6A3

Description	Sodium-dependent dopamine transporter

Gene and Protein Information

Gene ID	6531
Uniprot Accession IDs	A2RUN4 Q14996 DA transporter
Ensembl ID	ENSP00000270349
Symbol	DAT1 DAT DAT1 PKDYS PKDYS1
Family	Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. SLC6A3 subfamily.
Sequence	MSKSKCSVGLMSSVVAPAKEPNAVGPKEVELILVKEQNGVQLTSSTLTNPRQSPVEAQDRETWGKKIDFLLSVIGFAVDLANVWRFPYLCYKNGGGAFLVPYLLFMVIAGMPLFYMELALGQFNREGAAGVWKICPILKGVGFTVILISLYVGFFYNVIIAWALHYLFSSFTTELPWIHCNNSWNSPNCSDAHPGDSSGDSSGLNDTFGTTPAAEYFERGVLHLHQSHGIDDLGPPRWQLTACLVLVIVLLYFSLWKGVKTSGKVVWITATMPYVVLTALLLRGVTLPGAIDGIRAYLSVDFYRLCEASVWIDAATQVCFSLGVGFGVLIAFSSYNKFTNNCYRDAIVTTSINSLTSFSSGFVVFSFLGYMAQKHSVPIGDVAKDGPGLIFIIYPEAIATLPLSSAWAVVFFIMLLTLGIDSAMGGMESVITGLIDEFQLLHRHRELFTLFIVLATFLLSLFCVTNGGIYVFTLLDHFAAGTSILFGVLIEAIGVAWFYGVGQFSDDIQQMTGQRPSLYWRLCWKLVSPCFLLFVVVVSIVTFRPPHYGAYIFPDWANALGWVIATSSMAMVPIYAAYKFCSLPGSFREKLAYAIAPEKDRELVDRGEVRQFTLRHWLKV Show more

Homologous gene and protein info.

Species	Gene ID	Gene Symbol	Name	Tax ID	Other Gene ID	Sources
Chimp	750842	SLC6A3	solute carrier family 6 member 3	9598	VGNC:50806	OMA, EggNOG
Macaque	574143	SLC6A3	solute carrier family 6 member 3	9544		Inparanoid, OMA, EggNOG
Mouse	13162	Slc6a3	solute carrier family 6 (neurotransmitter transporter, dopamine), member 3	10090	MGI:94862	Inparanoid, OMA, EggNOG
Rat	24898	Slc6a3	solute carrier family 6 member 3	10116	RGD:3715	Inparanoid, OMA, EggNOG
Dog	609304	SLC6A3	solute carrier family 6 member 3	9615	VGNC:46464	Inparanoid, OMA, EggNOG
Horse	100054747	SLC6A3	solute carrier family 6 member 3	9796	VGNC:23260	Inparanoid, OMA, EggNOG
Pig	100521346	SLC6A3	solute carrier family 6 member 3	9823		OMA, EggNOG
Opossum	100015498	SLC6A3	solute carrier family 6 member 3	13616		Inparanoid, OMA, EggNOG
Platypus		SLC6A3	solute carrier family 6 member 3 [Source:HGNC Symbol;Acc:HGNC:11049]	9258		OMA, EggNOG

Protein Classes

PANTHER Classes
protein / transporter / cation transporter / Sodium-dependent dopamine transporter

DTO Classes
protein / Transporter / SLC superfamily of solute carriers / SLC6 neurotransmitter transporter family / Monoamine transporter subfamily / Sodium-dependent dopamine transporter

Associated Recombinant Proteins

Name	Specification and purity	Expression system	Protein label	Activity	View Details

Associated Antibodies

Name	Specifications	Species reactivity	species	Application	View Details

Associated Approved Drugs

Associated Active Ligands

Associated Diseases

Name	Disease Type	Mondoid

Pathway

Data Source	Name	Explore more targets	Explore in Source

🔙[Back to Target (Human)]