SLC6A3

DescriptionSodium-dependent dopamine transporter

Gene and Protein Information

Gene ID6531
Uniprot Accession IDs A2RUN4 Q14996 DA transporter
Ensembl ID ENSP00000270349
Symbol DAT1 DAT DAT1 PKDYS PKDYS1
FamilyBelongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. SLC6A3 subfamily.
Sequence
MSKSKCSVGLMSSVVAPAKEPNAVGPKEVELILVKEQNGVQLTSSTLTNPRQSPVEAQDRETWGKKIDFLLSVIGFAVDLANVWRFPYLCYKNGGGAFLVPYLLFMVIAGMPLFYMELALGQFNREGAAGVWKICPILKGVGFTVILISLYVGFFYNVIIAWALHYLFSSFTTELPWIHCNNSWNSPNCSDAHPGDSSGDSSGLNDTFGTTPAAEYFERGVLHLHQSHGIDDLGPPRWQLTACLVLVIVLLYFSLWKGVKTSGKVVWITATMPYVVLTALLLRGVTLPGAIDGIRAYLSVDFYRLCEASVWIDAATQVCFSLGVGFGVLIAFSSYNKFTNNCYRDAIVTTSINSLTSFSSGFVVFSFLGYMAQKHSVPIGDVAKDGPGLIFIIYPEAIATLPLSSAWAVVFFIMLLTLGIDSAMGGMESVITGLIDEFQLLHRHRELFTLFIVLATFLLSLFCVTNGGIYVFTLLDHFAAGTSILFGVLIEAIGVAWFYGVGQFSDDIQQMTGQRPSLYWRLCWKLVSPCFLLFVVVVSIVTFRPPHYGAYIFPDWANALGWVIATSSMAMVPIYAAYKFCSLPGSFREKLAYAIAPEKDRELVDRGEVRQFTLRHWLKV
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Homologous gene and protein info.
SpeciesGene IDGene SymbolNameTax IDOther Gene IDSources
Chimp750842SLC6A3solute carrier family 6 member 39598VGNC:50806OMA, EggNOG
Macaque574143SLC6A3solute carrier family 6 member 39544Inparanoid, OMA, EggNOG
Mouse13162Slc6a3solute carrier family 6 (neurotransmitter transporter, dopamine), member 310090MGI:94862Inparanoid, OMA, EggNOG
Rat24898Slc6a3solute carrier family 6 member 310116RGD:3715Inparanoid, OMA, EggNOG
Dog609304SLC6A3solute carrier family 6 member 39615VGNC:46464Inparanoid, OMA, EggNOG
Horse100054747SLC6A3solute carrier family 6 member 39796VGNC:23260Inparanoid, OMA, EggNOG
Pig100521346SLC6A3solute carrier family 6 member 39823OMA, EggNOG
Opossum100015498SLC6A3solute carrier family 6 member 313616Inparanoid, OMA, EggNOG
PlatypusSLC6A3solute carrier family 6 member 3 [Source:HGNC Symbol;Acc:HGNC:11049]9258OMA, EggNOG

Protein Classes

PANTHER Classes
protein    /    transporter    /    cation transporter    /    Sodium-dependent dopamine transporter
DTO Classes
protein    /    Transporter    /    SLC superfamily of solute carriers    /    SLC6 neurotransmitter transporter family    /    Monoamine transporter subfamily    /    Sodium-dependent dopamine transporter

Associated Recombinant Proteins

NameSpecification and purityExpression systemProtein labelAvailabilityView Details

Associated Antibodies

NameSpecificationsSpecies reactivityApplicationAvailabilityView Details

Associated Approved Drugs

    Associated Active Ligands

      Associated Diseases

      NameDirect Associated TargetsDisease TypeMondoid

      Pathway

      Data SourceNameExplore more targetsExplore in Source