SCN5A
| Description | Sodium channel protein type 5 subunit alpha |
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Gene and Protein Information
| Gene ID | 6331 |
|---|---|
| Uniprot Accession IDs | A5H1P8 A6N922 A6N923 B2RTU0 E7ET19 E9PEF3 E9PEK2 E9PFW7 Q59H93 Q75RX9 Q75RY0 Q86UR3 Q8IZC9 Q96J69 |
| Ensembl ID | ENSP00000410257 |
| Symbol | HB1 HB2 HH1 IVF VF1 HBBD ICCD LQT3 SSS1 CDCD2 CMD1E CMPD2 PFHB1 Nav1.5 |
| Family | Belongs to the sodium channel (TC 1.A.1.10) family. Nav1.5/SCN5A subfamily. |
| Sequence | MANFLLPRGTSSFRRFTRESLAAIEKRMAEKQARGSTTLQESREGLPEEEAPRPQLDLQASKKLPDLYGNPPQELIGEPLEDLDPFYSTQKTFIVLNKGKTIFRFSATNALYVLSPFHPIRRAAVKILVHSLFNMLIMCTILTNCVFMAQHDPPPWTKYVEYTFTAIYTFESLVKILARGFCLHAFTFLRDPWNWLDFSVIIMAYTTEFVDLGNVSALRTFRVLRALKTISVISGLKTIVGALIQSVKKLADVMVLTVFCLSVFALIGLQLFMGNLRHKCVRNFTALNGTNGSVEADGLVWESLDLYLSDPENYLLKNGTSDVLLCGNSSDAGTCPEGYRCLKAGENPDHGYTSFDSFAWAFLALFRLMTQDCWERLYQQTLRSAGKIYMIFFMLVIFLGSFYLVNLILAVVAMAYEEQNQATIAETEEKEKRFQEAMEMLKKEHEALTIRGVDTVSRSSLEMSPLAPVNSHERRSKRRKRMSSGTEECGEDRLPKSDSEDGPRAMNHLSLTRGLSRTSMKPRSSRGSIFTFRRRDLGSEADFADDENSTAGESESHHTSLLVPWPLRRTSAQGQPSPGTSAPGHALHGKKNSTVDCNGVVSLLGAGDPEATSPGSHLLRPVMLEHPPDTTTPSEEPGGPQMLTSQAPCVDGFEEPGARQRALSAVSVLTSALEELEESRHKCPPCWNRLAQRYLIWECCPLWMSIKQGVKLVVMDPFTDLTITMCIVLNTLFMALEHYNMTSEFEEMLQVGNLVFTGIFTAEMTFKIIALDPYYYFQQGWNIFDSIIVILSLMELGLSRMSNLSVLRSFRLLRVFKLAKSWPTLNTLIKIIGNSVGALGNLTLVLAIIVFIFAVVGMQLFGKNYSELRDSDSGLLPRWHMMDFFHAFLIIFRILCGEWIETMWDCMEVSGQSLCLLVFLLVMVIGNLVVLNLFLALLLSSFSADNLTAPDEDREMNNLQLALARIQRGLRFVKRTTWDFCCGLLRQRPQKPAALAAQGQLPSCIATPYSPPPPETEKVPPTRKETRFEEGEQPGQGTPGDPEPVCVPIAVAESDTDDQEEDEENSLGTEEESSKQQESQPVSGGPEAPPDSRTWSQVSATASSEAEASASQADWRQQWKAEPQAPGCGETPEDSCSEGSTADMTNTAELLEQIPDLGQDVKDPEDCFTEGCVRRCPCCAVDTTQAPGKVWWRLRKTCYHIVEHSWFETFIIFMILLSSGALAFEDIYLEERKTIKVLLEYADKMFTYVFVLEMLLKWVAYGFKKYFTNAWCWLDFLIVDVSLVSLVANTLGFAEMGPIKSLRTLRALRPLRALSRFEGMRVVVNALVGAIPSIMNVLLVCLIFWLIFSIMGVNLFAGKFGRCINQTEGDLPLNYTIVNNKSQCESLNLTGELYWTKVKVNFDNVGAGYLALLQVATFKGWMDIMYAAVDSRGYEEQPQWEYNLYMYIYFVIFIIFGSFFTLNLFIGVIIDNFNQQKKKLGGQDIFMTEEQKKYYNAMKKLGSKKPQKPIPRPLNKYQGFIFDIVTKQAFDVTIMFLICLNMVTMMVETDDQSPEKINILAKINLLFVAIFTGECIVKLAALRHYYFTNSWNIFDFVVVILSIVGTVLSDIIQKYFFSPTLFRVIRLARIGRILRLIRGAKGIRTLLFALMMSLPALFNIGLLLFLVMFIYSIFGMANFAYVKWEAGIDDMFNFQTFANSMLCLFQITTSAGWDGLLSPILNTGPPYCDPTLPNSNGSRGDCGSPAVGILFFTTYIIISFLIVVNMYIAIILENFSVATEESTEPLSEDDFDMFYEIWEKFDPEATQFIEYSVLSDFADALSEPLRIAKPNQISLINMDLPMVSGDRIHCMDILFAFTKRVLGESGEMDALKIQMEEKFMAANPSKISYEPITTTLRRKHEEVSAMVIQRAFRRHLLQRSLKHASFLFRQQAGSGLSEEDAPEREGLIAYVMSENFSRPLGPPSSSSISSTSFPPSYDSVTRATSDNLQVRGSDYSHSEDLADFPPSPDRDRESIV Show more |
Homologous gene and protein info.
| Species | Gene ID | Gene Symbol | Name | Tax ID | Other Gene ID | Sources |
|---|---|---|---|---|---|---|
| Chimp | 747523 | SCN5A | sodium voltage-gated channel alpha subunit 5 | 9598 | VGNC:12183 | OMA, EggNOG |
| Macaque | 695085 | SCN5A | sodium voltage-gated channel alpha subunit 5 | 9544 | OMA, EggNOG | |
| Mouse | 20271 | Scn5a | sodium channel, voltage-gated, type V, alpha | 10090 | MGI:98251 | Inparanoid, OMA, EggNOG |
| Rat | 25665 | Scn5a | sodium voltage-gated channel alpha subunit 5 | 10116 | RGD:3637 | Inparanoid, OMA, EggNOG |
| Dog | 403497 | SCN5A | sodium voltage-gated channel alpha subunit 5 | 9615 | VGNC:45921 | Inparanoid, OMA, EggNOG |
| Horse | 100034027 | SCN5A | sodium voltage-gated channel alpha subunit 5 | 9796 | VGNC:22740 | Inparanoid, OMA, EggNOG |
| Cow | 282061 | SCN5A | sodium voltage-gated channel alpha subunit 5 | 9913 | VGNC:34352 | Inparanoid, OMA, EggNOG |
| Pig | 100152567 | SCN5A | sodium voltage-gated channel alpha subunit 5 | 9823 | OMA, EggNOG | |
| Opossum | 100653514 | SCN5A | sodium voltage-gated channel alpha subunit 5 | 13616 | Inparanoid, OMA, EggNOG | |
| Chicken | 395947 | SCN5A | sodium voltage-gated channel alpha subunit 5 | 9031 | CGNC:49568 | Inparanoid, OMA |
Protein Classes
PANTHER Classes
protein / transporter / calcium channel / Sodium channel protein type 5 subunit alpha
protein / transporter / voltage-gated sodium channel / Sodium channel protein type 5 subunit alpha
protein / transporter / voltage-gated calcium channel / Sodium channel protein type 5 subunit alpha
protein / transporter / sodium channel / Sodium channel protein type 5 subunit alpha
protein / transporter / voltage-gated ion channel / Sodium channel protein type 5 subunit alpha
protein / transporter / calcium channel / Sodium channel protein type 5 subunit alpha
protein / transporter / voltage-gated sodium channel / Sodium channel protein type 5 subunit alpha
protein / transporter / voltage-gated calcium channel / Sodium channel protein type 5 subunit alpha
protein / transporter / sodium channel / Sodium channel protein type 5 subunit alpha
protein / transporter / voltage-gated ion channel / Sodium channel protein type 5 subunit alpha
DTO Classes
protein / Ion channel / Sodium channel family / Nav1.5/SCN5A subfamily / Sodium channel protein type 5 subunit alpha
protein / Ion channel / Sodium channel family / Nav1.5/SCN5A subfamily / Sodium channel protein type 5 subunit alpha
Associated Recombinant Proteins
| Name | Specification and purity | Expression system | Protein label | Activity | View Details |
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Associated Antibodies
| Name | Specifications | Species reactivity | species | Application | View Details |
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Associated Approved Drugs
Associated Active Ligands
Associated Diseases
| Name | Disease Type | Mondoid |
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Pathway
| Data Source | Name | Explore more targets | Explore in Source |
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