Protein or Target Summary
Sodium channel protein type 5 subunit alpha
| Gene ID | 6331 |
|---|---|
| uniprot | Q14524 |
| Gene Name | SCN5A |
| Ensernbl ID | ENSP00000410257 |
| Family | Belongs to the sodium channel (TC 1.A.1.10) family. Nav1.5/SCN5A subfamily. |
| Sequence | MANFLLPRGTSSFRRFTRESLAAIEKRMAEKQARGSTTLQESREGLPEEEAPRPQLDLQASKKLPDLYGNPPQELIGEPLEDLDPFYSTQKTFIVLNKGKTIFRFSATNALYVLSPFHPIRRAAVKILVHSLFNMLIMCTILTNCVFMAQHDPPPWTKYVEYTFTAIYTFESLVKILARGFCLHAFTFLRDPWNWLDFSVIIMAYTTEFVDLGNVSALRTFRVLRALKTISVISGLKTIVGALIQSVKKLADVMVLTVFCLSVFALIGLQLFMGNLRHKCVRNFTALNGTNGSVEADGLVWESLDLYLSDPENYLLKNGTSDVLLCGNSSDAGTCPEGYRCLKAGENPDHGYTSFDSFAWAFLALFRLMTQDCWERLYQQTLRSAGKIYMIFFMLVIFLGSFYLVNLILAVVAMAYEEQNQATIAETEEKEKRFQEAMEMLKKEHEALTIRGVDTVSRSSLEMSPLAPVNSHERRSKRRKRMSSGTEECGEDRLPKSDSEDGPRAMNHLSLTRGLSRTSMKPRSSRGSIFTFRRRDLGSEADFADDENSTAGESESHHTSLLVPWPLRRTSAQGQPSPGTSAPGHALHGKKNSTVDCNGVVSLLGAGDPEATSPGSHLLRPVMLEHPPDTTTPSEEPGGPQMLTSQAPCVDGFEEPGARQRALSAVSVLTSALEELEESRHKCPPCWNRLAQRYLIWECCPLWMSIKQGVKLVVMDPFTDLTITMCIVLNTLFMALEHYNMTSEFEEMLQVGNLVFTGIFTAEMTFKIIALDPYYYFQQGWNIFDSIIVILSLMELGLSRMSNLSVLRSFRLLRVFKLAKSWPTLNTLIKIIGNSVGALGNLTLVLAIIVFIFAVVGMQLFGKNYSELRDSDSGLLPRWHMMDFFHAFLIIFRILCGEWIETMWDCMEVSGQSLCLLVFLLVMVIGNLVVLNLFLALLLSSFSADNLTAPDEDREMNNLQLALARIQRGLRFVKRTTWDFCCGLLRQRPQKPAALAAQGQLPSCIATPYSPPPPETEKVPPTRKETRFEEGEQPGQGTPGDPEPVCVPIAVAESDTDDQEEDEENSLGTEEESSKQQESQPVSGGPEAPPDSRTWSQVSATASSEAEASASQADWRQQWKAEPQAPGCGETPEDSCSEGSTADMTNTAELLEQIPDLGQDVKDPEDCFTEGCVRRCPCCAVDTTQAPGKVWWRLRKTCYHIVEHSWFETFIIFMILLSSGALAFEDIYLEERKTIKVLLEYADKMFTYVFVLEMLLKWVAYGFKKYFTNAWCWLDFLIVDVSLVSLVANTLGFAEMGPIKSLRTLRALRPLRALSRFEGMRVVVNALVGAIPSIMNVLLVCLIFWLIFSIMGVNLFAGKFGRCINQTEGDLPLNYTIVNNKSQCESLNLTGELYWTKVKVNFDNVGAGYLALLQVATFKGWMDIMYAAVDSRGYEEQPQWEYNLYMYIYFVIFIIFGSFFTLNLFIGVIIDNFNQQKKKLGGQDIFMTEEQKKYYNAMKKLGSKKPQKPIPRPLNKYQGFIFDIVTKQAFDVTIMFLICLNMVTMMVETDDQSPEKINILAKINLLFVAIFTGECIVKLAALRHYYFTNSWNIFDFVVVILSIVGTVLSDIIQKYFFSPTLFRVIRLARIGRILRLIRGAKGIRTLLFALMMSLPALFNIGLLLFLVMFIYSIFGMANFAYVKWEAGIDDMFNFQTFANSMLCLFQITTSAGWDGLLSPILNTGPPYCDPTLPNSNGSRGDCGSPAVGILFFTTYIIISFLIVVNMYIAIILENFSVATEESTEPLSEDDFDMFYEIWEKFDPEATQFIEYSVLSDFADALSEPLRIAKPNQISLINMDLPMVSGDRIHCMDILFAFTKRVLGESGEMDALKIQMEEKFMAANPSKISYEPITTTLRRKHEEVSAMVIQRAFRRHLLQRSLKHASFLFRQQAGSGLSEEDAPEREGLIAYVMSENFSRPLGPPSSSSISSTSFPPSYDSVTRATSDNLQVRGSDYSHSEDLADFPPSPDRDRESIV Show more |
Gene and Protein Information
| Species | Gene ID | Gene Symbol | Gene Name | Uniprot |
|---|---|---|---|---|
| HUMAN | 6331 | SCN5A | Sodium channel protein type 5 subunit alpha | Q14524 |
| MOUSE | Scn5a | Sodium channel voltage-gated type V alpha polypeptide | D0ENM2 | |
| MOUSE | Scn5a | Sodium channel protein | A0A0R5RP31 | |
| MOUSE | 20271 | Scn5a | Uncharacterized protein | Q8C3I3 |
| MOUSE | Scn5a | Sodium channel protein | A0A0R5RP25 | |
| MOUSE | Scn5a | Voltage-gated sodium channel Nav1.5 | Q6EWG3 | |
| MOUSE | Scn5a | Voltage-gated sodium channel Nav1.5c | Q6EWG4 | |
| MOUSE | 20271 | Scn5a | Sodium channel protein | A0A0R4J1M7 |
| MOUSE | Scn5a | Sodium channel protein type 5 subunit alpha | D3YXW2 | |
| MOUSE | 20271 | Scn5a | Sodium channel protein | K3W4N7 |
| MOUSE | 20271 | Scn5a | Sodium channel protein type 5 subunit alpha | Q9JJV9 |
| RAT | 25665 | Scn5a | Sodium channel protein type 5 subunit alpha | P15389 |
| RAT | 25665 | Scn5a | Sodium channel protein | F1LPK3 |
| RAT | Scn5a | Sodium channel protein | F1LNF5 | |
| RAT | Scn5a | Voltage-gated sodium channel type V alpha subunit variant | A4ZYR8 | |
| RAT | scn5A | Voltage-gated sodium channel Nav1.5c | Q6EWG5 | |
| RAT | 25665 | Scn5a | Sodium channel protein | A0A0G2JWG8 |
Protein Classes
PANTHER Classes
protein / transporter / calcium channel / Sodium channel protein type 5 subunit alpha
protein / transporter / voltage-gated sodium channel / Sodium channel protein type 5 subunit alpha
protein / transporter / voltage-gated calcium channel / Sodium channel protein type 5 subunit alpha
protein / transporter / sodium channel / Sodium channel protein type 5 subunit alpha
protein / transporter / voltage-gated ion channel / Sodium channel protein type 5 subunit alpha
protein / transporter / calcium channel / Sodium channel protein type 5 subunit alpha
protein / transporter / voltage-gated sodium channel / Sodium channel protein type 5 subunit alpha
protein / transporter / voltage-gated calcium channel / Sodium channel protein type 5 subunit alpha
protein / transporter / sodium channel / Sodium channel protein type 5 subunit alpha
protein / transporter / voltage-gated ion channel / Sodium channel protein type 5 subunit alpha
DTO Classes
protein / Ion channel / Sodium channel family / Nav1.5/SCN5A subfamily / Sodium channel protein type 5 subunit alpha
protein / Ion channel / Sodium channel family / Nav1.5/SCN5A subfamily / Sodium channel protein type 5 subunit alpha
Associated Recombinant Proteins
| Name | Specification and purity | Expression system | Protein label | Activity | View Details |
|---|
Associated Antibodies
| Name | Specifications | Species reactivity | species | Application | View Details |
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Associated Approved Drugs
Associated Active Ligands
Associated Diseases
| Name | Disease Type | Mondoid |
|---|
Pathway
| Data Source | Name | Explore more targets | Explore in Source |
|---|
Source: DataSourcesLicenses.xlsx