| Description | Sodium channel protein type 10 subunit alpha |
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Gene and Protein Information
| Gene ID | 6336 |
|---|---|
| Uniprot Accession IDs | A6NDQ1 |
| Ensembl ID | ENSP00000390600 |
| Symbol | PN3 SNS hPN3 FEPS2 Nav1.8 |
| Family | Belongs to the sodium channel (TC 1.A.1.10) family. Nav1.8/SCN10A subfamily. |
| Sequence | MEFPIGSLETNNFRRFTPESLVEIEKQIAAKQGTKKAREKHREQKDQEEKPRPQLDLKACNQLPKFYGELPAELIGEPLEDLDPFYSTHRTFMVLNKGRTISRFSATRALWLFSPFNLIRRTAIKVSVHSWFSLFITVTILVNCVCMTRTDLPEKIEYVFTVIYTFEALIKILARGFCLNEFTYLRDPWNWLDFSVITLAYVGTAIDLRGISGLRTFRVLRALKTVSVIPGLKVIVGALIHSVKKLADVTILTIFCLSVFALVGLQLFKGNLKNKCVKNDMAVNETTNYSSHRKPDIYINKRGTSDPLLCGNGSDSGHCPDGYICLKTSDNPDFNYTSFDSFAWAFLSLFRLMTQDSWERLYQQTLRTSGKIYMIFFVLVIFLGSFYLVNLILAVVTMAYEEQNQATTDEIEAKEKKFQEALEMLRKEQEVLAALGIDTTSLHSHNGSPLTSKNASERRHRIKPRVSEGSTEDNKSPRSDPYNQRRMSFLGLASGKRRASHGSVFHFRSPGRDISLPEGVTDDGVFPGDHESHRGSLLLGGGAGQQGPLPRSPLPQPSNPDSRHGEDEHQPPPTSELAPGAVDVSAFDAGQKKTFLSAEYLDEPFRAQRAMSVVSIITSVLEELEESEQKCPPCLTSLSQKYLIWDCCPMWVKLKTILFGLVTDPFAELTITLCIVVNTIFMAMEHHGMSPTFEAMLQIGNIVFTIFFTAEMVFKIIAFDPYYYFQKKWNIFDCIIVTVSLLELGVAKKGSLSVLRSFRLLRVFKLAKSWPTLNTLIKIIGNSVGALGNLTIILAIIVFVFALVGKQLLGENYRNNRKNISAPHEDWPRWHMHDFFHSFLIVFRILCGEWIENMWACMEVGQKSICLILFLTVMVLGNLVVLNLFIALLLNSFSADNLTAPEDDGEVNNLQVALARIQVFGHRTKQALCSFFSRSCPFPQPKAEPELVVKLPLSSSKAENHIAANTARGSSGGLQAPRGPRDEHSDFIANPTVWVSVPIAEGESDLDDLEDDGGEDAQSFQQEVIPKGQQEQLQQVERCGDHLTPRSPGTGTSSEDLAPSLGETWKDESVPQVPAEGVDDTSSSEGSTVDCLDPEEILRKIPELADDLEEPDDCFTEGCIRHCPCCKLDTTKSPWDVGWQVRKTCYRIVEHSWFESFIIFMILLSSGSLAFEDYYLDQKPTVKALLEYTDRVFTFIFVFEMLLKWVAYGFKKYFTNAWCWLDFLIVNISLISLTAKILEYSEVAPIKALRTLRALRPLRALSRFEGMRVVVDALVGAIPSIMNVLLVCLIFWLIFSIMGVNLFAGKFWRCINYTDGEFSLVPLSIVNNKSDCKIQNSTGSFFWVNVKVNFDNVAMGYLALLQVATFKGWMDIMYAAVDSREVNMQPKWEDNVYMYLYFVIFIIFGGFFTLNLFVGVIIDNFNQQKKKLGGQDIFMTEEQKKYYNAMKKLGSKKPQKPIPRPLNKFQGFVFDIVTRQAFDITIMVLICLNMITMMVETDDQSEEKTKILGKINQFFVAVFTGECVMKMFALRQYYFTNGWNVFDFIVVVLSIASLIFSAILKSLQSYFSPTLFRVIRLARIGRILRLIRAAKGIRTLLFALMMSLPALFNIGLLLFLVMFIYSIFGMSSFPHVRWEAGIDDMFNFQTFANSMLCLFQITTSAGWDGLLSPILNTGPPYCDPNLPNSNGTRGDCGSPAVGIIFFTTYIIISFLIMVNMYIAVILENFNVATEESTEPLSEDDFDMFYETWEKFDPEATQFITFSALSDFADTLSGPLRIPKPNRNILIQMDLPLVPGDKIHCLDILFAFTKNVLGESGELDSLKANMEEKFMATNLSKSSYEPIATTLRWKQEDISATVIQKAYRSYVLHRSMALSNTPCVPRAEEEAASLPDEGFVAFTANENCVLPDKSETASATSFPPSYESVTRGLSDRVNMRTSSSIQNEDEATSMELIAPGP Show more |
Homologous gene and protein info.
| Species | Gene ID | Gene Symbol | Name | Tax ID | Other Gene ID | Sources |
|---|---|---|---|---|---|---|
| Chimp | 460274 | SCN10A | sodium voltage-gated channel alpha subunit 10 | 9598 | VGNC:12180 | OMA, EggNOG |
| Macaque | 694962 | SCN10A | sodium voltage-gated channel alpha subunit 10 | 9544 | Inparanoid, OMA, EggNOG | |
| Mouse | 20264 | Scn10a | sodium channel, voltage-gated, type X, alpha | 10090 | MGI:108029 | Inparanoid, OMA, EggNOG |
| Rat | 29571 | Scn10a | sodium voltage-gated channel alpha subunit 10 | 10116 | RGD:3629 | Inparanoid, OMA, EggNOG |
| Dog | 477026 | SCN10A | sodium voltage-gated channel alpha subunit 10 | 9615 | VGNC:45913 | Inparanoid, OMA, EggNOG |
| Horse | 100055493 | SCN10A | sodium voltage-gated channel alpha subunit 10 | 9796 | VGNC:22730 | Inparanoid, OMA, EggNOG |
| Cow | 100299477 | SCN10A | sodium voltage-gated channel alpha subunit 10 | 9913 | VGNC:34343 | Inparanoid, OMA, EggNOG |
| Pig | 100518274 | SCN10A | sodium voltage-gated channel alpha subunit 10 | 9823 | OMA, EggNOG | |
| Opossum | 100020766 | SCN10A | sodium voltage-gated channel alpha subunit 10 | 13616 | Inparanoid, OMA, EggNOG | |
| Anole lizard | 100560187 | LOC100560187 | sodium channel protein type 5 subunit alpha | 28377 | OMA, EggNOG |
Protein Classes
PANTHER Classes
protein / transporter / calcium channel / Sodium channel protein type 10 subunit alpha
protein / transporter / voltage-gated sodium channel / Sodium channel protein type 10 subunit alpha
protein / transporter / voltage-gated calcium channel / Sodium channel protein type 10 subunit alpha
protein / transporter / sodium channel / Sodium channel protein type 10 subunit alpha
protein / transporter / voltage-gated ion channel / Sodium channel protein type 10 subunit alpha
protein / transporter / calcium channel / Sodium channel protein type 10 subunit alpha
protein / transporter / voltage-gated sodium channel / Sodium channel protein type 10 subunit alpha
protein / transporter / voltage-gated calcium channel / Sodium channel protein type 10 subunit alpha
protein / transporter / sodium channel / Sodium channel protein type 10 subunit alpha
protein / transporter / voltage-gated ion channel / Sodium channel protein type 10 subunit alpha
DTO Classes
protein / Ion channel / Sodium channel family / Nav1.8/SCN10A subfamily / Sodium channel protein type 10 subunit alpha
protein / Ion channel / Sodium channel family / Nav1.8/SCN10A subfamily / Sodium channel protein type 10 subunit alpha
Associated Recombinant Proteins
| Name | Specification and purity | Expression system | Protein label | Activity | View Details |
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Associated Antibodies
| Name | Specifications | Species reactivity | species | Application | View Details |
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Associated Approved Drugs
Associated Active Ligands
Associated Diseases
| Name | Disease Type | Mondoid |
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Pathway
| Data Source | Name | Explore more targets | Explore in Source |
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