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SLC12A2

Description	Solute carrier family 12 member 2

Gene and Protein Information

Gene ID	6558
Uniprot Accession IDs	Q8N713 Q8WWH7
Ensembl ID	ENSP00000262461
Symbol	NKCC1 BSC BSC2 NKCC1 PPP1R141
Family	Belongs to the SLC12A transporter family.
Sequence	MEPRPTAPSSGAPGLAGVGETPSAAALAAARVELPGTAVPSVPEDAAPASRDGGGVRDEGPAAAGDGLGRPLGPTPSQSRFQVDLVSENAGRAAAAAAAAAAAAAAAGAGAGAKQTPADGEASGESEPAKGSEEAKGRFRVNFVDPAASSSAEDSLSDAAGVGVDGPNVSFQNGGDTVLSEGSSLHSGGGGGSGHHQHYYYDTHTNTYYLRTFGHNTMDAVPRIDHYRHTAAQLGEKLLRPSLAELHDELEKEPFEDGFANGEESTPTRDAVVTYTAESKGVVKFGWIKGVLVRCMLNIWGVMLFIRLSWIVGQAGIGLSVLVIMMATVVTTITGLSTSAIATNGFVRGGGAYYLISRSLGPEFGGAIGLIFAFANAVAVAMYVVGFAETVVELLKEHSILMIDEINDIRIIGAITVVILLGISVAGMEWEAKAQIVLLVILLLAIGDFVIGTFIPLESKKPKGFFGYKSEIFNENFGPDFREEETFFSVFAIFFPAATGILAGANISGDLADPQSAIPKGTLLAILITTLVYVGIAVSVGSCVVRDATGNVNDTIVTELTNCTSAACKLNFDFSSCESSPCSYGLMNNFQVMSMVSGFTPLISAGIFSATLSSALASLVSAPKIFQALCKDNIYPAFQMFAKGYGKNNEPLRGYILTFLIALGFILIAELNVIAPIISNFFLASYALINFSVFHASLAKSPGWRPAFKYYNMWISLLGAILCCIVMFVINWWAALLTYVIVLGLYIYVTYKKPDVNWGSSTQALTYLNALQHSIRLSGVEDHVKNFRPQCLVMTGAPNSRPALLHLVHDFTKNVGLMICGHVHMGPRRQAMKEMSIDQAKYQRWLIKNKMKAFYAPVHADDLREGAQYLMQAAGLGRMKPNTLVLGFKKDWLQADMRDVDMYINLFHDAFDIQYGVVVIRLKEGLDISHLQGQEELLSSQEKSPGTKDVVVSVEYSKKSDLDTSKPLSEKPITHKVEEEDGKTATQPLLKKESKGPIVPLNVADQKLLEASTQFQKKQGKNTIDVWWLFDDGGLTLLIPYLLTTKKKWKDCKIRVFIGGKINRIDHDRRAMATLLSKFRIDFSDIMVLGDINTKPKKENIIAFEEIIEPYRLHEDDKEQDIADKMKEDEPWRITDNELELYKTKTYRQIRLNELLKEHSSTANIIVMSLPVARKGAVSSALYMAWLEALSKDLPPILLVRGNHQSVLTFYS Show more

Homologous gene and protein info.

Species	Gene ID	Gene Symbol	Name	Tax ID	Other Gene ID	Sources
Chimp	471620	SLC12A2	solute carrier family 12 member 2	9598	VGNC:8637	OMA, EggNOG
Macaque	704672	SLC12A2	solute carrier family 12 member 2	9544		Inparanoid, OMA, EggNOG
Mouse	20496	Slc12a2	solute carrier family 12, member 2	10090	MGI:101924	Inparanoid, OMA, EggNOG
Rat	83629	Slc12a2	solute carrier family 12 member 2	10116	RGD:620809	Inparanoid, OMA, EggNOG
Dog	481490	SLC12A2	solute carrier family 12 member 2	9615	VGNC:46219	Inparanoid, OMA, EggNOG
Horse	100073036	SLC12A2	solute carrier family 12 member 2	9796	VGNC:23020	Inparanoid, OMA, EggNOG
Cow	286845	SLC12A2	solute carrier family 12 member 2	9913	VGNC:34665	Inparanoid, OMA, EggNOG
Pig	100516960	SLC12A2	solute carrier family 12 member 2	9823		Inparanoid, OMA, EggNOG
Opossum	100022720	SLC12A2	solute carrier family 12 member 2	13616		Inparanoid, OMA, EggNOG
Chicken	427123	SLC12A2	solute carrier family 12 member 2	9031	CGNC:10891	Inparanoid, OMA
Anole lizard	100555453	slc12a2	solute carrier family 12 member 2	28377		Inparanoid, OMA
Zebrafish	415170	slc12a2	solute carrier family 12 (sodium/potassium/chloride transporter), member 2	7955		Inparanoid, OMA

Protein Classes

DTO Classes
protein / Transporter / SLC superfamily of solute carriers / SLC12 family of cation-coupled chloride transporters / Solute carrier family 12 member 2

Associated Recombinant Proteins

Name	Specification and purity	Expression system	Protein label	Activity	View Details

Associated Antibodies

Name	Specifications	Species reactivity	species	Application	View Details

Associated Approved Drugs

Associated Active Ligands

Associated Diseases

Name	Disease Type	Mondoid

Pathway

Data Source	Name	Explore more targets	Explore in Source

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