SLC12A3

DescriptionSolute carrier family 12 member 3

Gene and Protein Information

Gene ID6559
Uniprot Accession IDs A8MSJ2 C9JNN9
Ensembl ID ENSP00000402152
Symbol NCC TSC NCC TSC NCCT
FamilyBelongs to the SLC12A transporter family.
Sequence
MAELPTTETPGDATLCSGRFTISTLLSSDEPSPPAAYDSSHPSHLTHSSTFCMRTFGYNTIDVVPTYEHYANSTQPGEPRKVRPTLADLHSFLKQEGRHLHALAFDSRPSHEMTDGLVEGEAGTSSEKNPEEPVRFGWVKGVMIRCMLNIWGVILYLRLPWITAQAGIVLTWIIILLSVTVTSITGLSISAISTNGKVKSGGTYFLISRSLGPELGGSIGLIFAFANAVGVAMHTVGFAETVRDLLQEYGAPIVDPINDIRIIAVVSVTVLLAISLAGMEWESKAQVLFFLVIMVSFANYLVGTLIPPSEDKASKGFFSYRADIFVQNLVPDWRGPDGTFFGMFSIFFPSATGILAGANISGDLKDPAIAIPKGTLMAIFWTTISYLAISATIGSCVVRDASGVLNDTVTPGWGACEGLACSYGWNFTECTQQHSCHYGLINYYQTMSMVSGFAPLITAGIFGATLSSALACLVSAAKVFQCLCEDQLYPLIGFFGKGYGKNKEPVRGYLLAYAIAVAFIIIAELNTIAPIISNFFLCSYALINFSCFHASITNSPGWRPSFQYYNKWAALFGAIISVVIMFLLTWWAALIAIGVVLFLLLYVIYKKPEVNWGSSVQAGSYNLALSYSVGLNEVEDHIKNYRPQCLVLTGPPNFRPALVDFVGTFTRNLSLMICGHVLIGPHKQRMPELQLIANGHTKWLNKRKIKAFYSDVIAEDLRRGVQILMQAAGLGRMKPNILVVGFKKNWQSAHPATVEDYIGILHDAFDFNYGVCVMRMREGLNVSKMMQAHINPVFDPAEDGKEASARVDPKALVKEEQATTIFQSEQGKKTIDIYWLFDDGGLTLLIPYLLGRKRRWSKCKIRVFVGGQINRMDQERKAIISLLSKFRLGFHEVHILPDINQNPRAEHTKRFEDMIAPFRLNDGFKDEATVNEMRRDCPWKISDEEITKNRVKSLRQVRLNEIVLDYSRDAALIVITLPIGRKGKCPSSLYMAWLETLSQDLRPPVILIRGNQENVLTFYCQ
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Homologous gene and protein info.
SpeciesGene IDGene SymbolNameTax IDOther Gene IDSources
Chimp454108SLC12A3solute carrier family 12 member 39598VGNC:9011OMA, EggNOG
Macaque703090SLC12A3solute carrier family 12 member 39544Inparanoid, OMA, EggNOG
Mouse20497Slc12a3solute carrier family 12, member 310090MGI:108114Inparanoid, OMA, EggNOG
Rat54300Slc12a3solute carrier family 12 member 310116RGD:3686Inparanoid, OMA
Dog478118SLC12A3solute carrier family 12 member 39615VGNC:46220Inparanoid, OMA, EggNOG
Horse100051953SLC12A3solute carrier family 12 member 39796VGNC:51307Inparanoid, OMA, EggNOG
Cow404171SLC12A3solute carrier family 12 member 39913VGNC:34666Inparanoid, OMA, EggNOG
Opossum100015656SLC12A3solute carrier family 12 member 313616Inparanoid, EggNOG
Chicken415692SLC12A3solute carrier family 12 member 39031CGNC:2136Inparanoid, OMA
Anole lizard100562387slc12a3solute carrier family 12 member 328377OMA, EggNOG
Xenopus100494755slc12a3solute carrier family 12 member 38364XB-GENE-866805Inparanoid, OMA
Zebrafish565439slc12a3solute carrier family 12 (sodium/chloride transporter), member 37955ZDB-GENE-030131-9505Inparanoid, OMA, EggNOG
C. elegans3565648nkcc-1Na-K-Cl Cotransporter homolog6239Inparanoid, EggNOG

Protein Classes

DTO Classes
protein    /    Transporter    /    SLC superfamily of solute carriers    /    SLC12 family of cation-coupled chloride transporters    /    Solute carrier family 12 member 3

Associated Recombinant Proteins

NameSpecification and purityExpression systemProtein labelActivityView Details

Associated Antibodies

NameSpecificationsSpecies reactivityspeciesApplicationView Details

Associated Approved Drugs

    Associated Active Ligands

      Associated Diseases

      NameDisease TypeMondoid

      Pathway

      Data SourceNameExplore more targetsExplore in Source