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Protein or Target Summary

Phospholipid hydroperoxide glutathione peroxidase

Gene ID2879
uniprotP36969
Gene NameGPX4
Ensernbl IDENSP00000346103
FamilyBelongs to the glutathione peroxidase family.
Sequence
MSLGRLCRLLKPALLCGALAAPGLAGTMCASRDDWRCARSMHEFSAKDIDGHMVNLDKYRGFVCIVTNVASQUGKTEVNYTQLVDLHARYAECGLRILAFPCNQFGKQEPGSNEEIKEFAAGYNVKFDMFSKICVNGDDAHPLWKWMKIQPKGKGILGNAIKWNFTKFLIDKNGCVVKRYGPMEEPLVIEKDLPHYF
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Gene and Protein Information

SpeciesGene IDGene SymbolGene NameUniprot
HUMAN2879GPX4Phospholipid hydroperoxide glutathione peroxidaseP36969
MOUSE625249Gpx4Phospholipid hydroperoxide glutathione peroxidaseO70325
MOUSEGpx4Uncharacterized proteinQ3TIF2
MOUSE625249Gpx4Glutathione peroxidaseQ76LV0
MOUSEGpx4Glutathione peroxidaseS4R1E5
MOUSEGpx4Glutathione peroxidaseQ5XJZ8
MOUSEGpx4Glutathione peroxidaseQ3TI34
RAT29328Gpx4Phospholipid hydroperoxide glutathione peroxidaseP36970
RATGpx4Glutathione peroxidaseF8WFK6
RATGpx4Glutathione peroxidaseA0A0G2K398

Protein Classes

PANTHER Classes
protein    /    oxidoreductase    /    peroxidase    /    Phospholipid hydroperoxide glutathione peroxidase, mitochondrial
DTO Classes
protein    /    Enzyme    /    Oxidoreductase    /    Peroxidase    /    Phospholipid hydroperoxide glutathione peroxidase, mitochondrial

Associated Recombinant Proteins

NameSpecification and purityExpression systemProtein labelActivityView Details

Associated Antibodies

NameSpecificationsSpecies reactivityspeciesApplicationView Details

Associated Approved Drugs

    Associated Active Ligands

      Associated Diseases

      NameDisease TypeMondoid

      Pathway

      Data SourceNameExplore more targetsExplore in Source