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Protein or Target Summary

Sodium-dependent serotonin transporter

Gene ID6532
uniprotP31645
Gene NameSLC6A4
Ensernbl IDENSP00000261707
FamilyBelongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. SLC6A4 subfamily.
Sequence
METTPLNSQKQLSACEDGEDCQENGVLQKVVPTPGDKVESGQISNGYSAVPSPGAGDDTRHSIPATTTTLVAELHQGERETWGKKVDFLLSVIGYAVDLGNVWRFPYICYQNGGGAFLLPYTIMAIFGGIPLFYMELALGQYHRNGCISIWRKICPIFKGIGYAICIIAFYIASYYNTIMAWALYYLISSFTDQLPWTSCKNSWNTGNCTNYFSEDNITWTLHSTSPAEEFYTRHVLQIHRSKGLQDLGGISWQLALCIMLIFTVIYFSIWKGVKTSGKVVWVTATFPYIILSVLLVRGATLPGAWRGVLFYLKPNWQKLLETGVWIDAAAQIFFSLGPGFGVLLAFASYNKFNNNCYQDALVTSVVNCMTSFVSGFVIFTVLGYMAEMRNEDVSEVAKDAGPSLLFITYAEAIANMPASTFFAIIFFLMLITLGLDSTFAGLEGVITAVLDEFPHVWAKRRERFVLAVVITCFFGSLVTLTFGGAYVVKLLEEYATGPAVLTVALIEAVAVSWFYGITQFCRDVKEMLGFSPGWFWRICWVAISPLFLLFIICSFLMSPPQLRLFQYNYPYWSIILGYCIGTSSFICIPTYIAYRLIITPGTFKERIIKSITPETPTEIPCGDIRLNAV
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Gene and Protein Information

SpeciesGene IDGene SymbolGene NameUniprot
HUMAN6532SLC6A4Sodium-dependent serotonin transporterP31645
MOUSE15567Slc6a4Sodium-dependent serotonin transporterQ60857
MOUSESlc6a4Serotonin transporterQ5UBE7
MOUSESlc6a4TransporterQ5NCR5
MOUSESlc6a4TransporterQ32MU4
RAT25553Slc6a4Sodium-dependent serotonin transporterP31652

Protein Classes

PANTHER Classes
protein    /    transporter    /    cation transporter    /    Sodium-dependent serotonin transporter
DTO Classes
protein    /    Transporter    /    SLC superfamily of solute carriers    /    SLC6 neurotransmitter transporter family    /    Monoamine transporter subfamily    /    Sodium-dependent serotonin transporter

Associated Recombinant Proteins

NameSpecification and purityExpression systemProtein labelActivityView Details

Associated Antibodies

NameSpecificationsSpecies reactivityspeciesApplicationView Details

Associated Approved Drugs

    Associated Active Ligands

      Associated Diseases

      NameDisease TypeMondoid

      Pathway

      Data SourceNameExplore more targetsExplore in Source