SLC6A4

Description	Sodium-dependent serotonin transporter

Gene and Protein Information

Gene ID	6532
Uniprot Accession IDs	Q5EE02 SERT
Ensembl ID	ENSP00000261707
Symbol	HTT SERT HTT 5HTT OCD1 SERT 5-HTT SERT1 hSERT 5-HTTLPR
Family	Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. SLC6A4 subfamily.
Sequence	METTPLNSQKQLSACEDGEDCQENGVLQKVVPTPGDKVESGQISNGYSAVPSPGAGDDTRHSIPATTTTLVAELHQGERETWGKKVDFLLSVIGYAVDLGNVWRFPYICYQNGGGAFLLPYTIMAIFGGIPLFYMELALGQYHRNGCISIWRKICPIFKGIGYAICIIAFYIASYYNTIMAWALYYLISSFTDQLPWTSCKNSWNTGNCTNYFSEDNITWTLHSTSPAEEFYTRHVLQIHRSKGLQDLGGISWQLALCIMLIFTVIYFSIWKGVKTSGKVVWVTATFPYIILSVLLVRGATLPGAWRGVLFYLKPNWQKLLETGVWIDAAAQIFFSLGPGFGVLLAFASYNKFNNNCYQDALVTSVVNCMTSFVSGFVIFTVLGYMAEMRNEDVSEVAKDAGPSLLFITYAEAIANMPASTFFAIIFFLMLITLGLDSTFAGLEGVITAVLDEFPHVWAKRRERFVLAVVITCFFGSLVTLTFGGAYVVKLLEEYATGPAVLTVALIEAVAVSWFYGITQFCRDVKEMLGFSPGWFWRICWVAISPLFLLFIICSFLMSPPQLRLFQYNYPYWSIILGYCIGTSSFICIPTYIAYRLIITPGTFKERIIKSITPETPTEIPCGDIRLNAV Show more

Homologous gene and protein info.

Species	Gene ID	Gene Symbol	Name	Tax ID	Other Gene ID	Sources
Chimp	468201	SLC6A4	solute carrier family 6 member 4	9598	VGNC:9626	OMA, EggNOG
Macaque	574140	SLC6A4	solute carrier family 6 member 4	9544		Inparanoid, OMA, EggNOG
Mouse	15567	Slc6a4	solute carrier family 6 (neurotransmitter transporter, serotonin), member 4	10090	MGI:96285	Inparanoid, OMA, EggNOG
Rat	25553	Slc6a4	solute carrier family 6 member 4	10116	RGD:3714	Inparanoid, OMA, EggNOG
Dog	491184	SLC6A4	solute carrier family 6 member 4	9615	VGNC:46465	Inparanoid, OMA, EggNOG
Horse	100033848	SLC6A4	solute carrier family 6 member 4	9796	VGNC:23261	OMA, EggNOG
Cow	282365	SLC6A4	solute carrier family 6 member 4	9913	VGNC:49971	Inparanoid, OMA, EggNOG
Pig	100517307	SLC6A4	solute carrier family 6 member 4	9823		OMA, EggNOG
Opossum	100015330	SLC6A4	solute carrier family 6 member 4	13616		Inparanoid, OMA, EggNOG
Chicken	404747	SLC6A4	solute carrier family 6 member 4	9031	CGNC:3120	Inparanoid, OMA, EggNOG
Anole lizard	100562250	slc6a4	solute carrier family 6 member 4	28377		Inparanoid, OMA, EggNOG
Zebrafish	664719	slc6a4a	solute carrier family 6 (neurotransmitter transporter), member 4a	7955	ZDB-GENE-060314-1	Inparanoid, OMA
C. elegans	171879	mod-5	Transporter	6239		Inparanoid, OMA

Protein Classes

PANTHER Classes
protein / transporter / cation transporter / Sodium-dependent serotonin transporter

DTO Classes
protein / Transporter / SLC superfamily of solute carriers / SLC6 neurotransmitter transporter family / Monoamine transporter subfamily / Sodium-dependent serotonin transporter

Associated Recombinant Proteins

Name	Specification and purity	Expression system	Protein label	Activity	View Details

Associated Antibodies

Name	Specifications	Species reactivity	species	Application	View Details

Associated Approved Drugs

Associated Active Ligands

Associated Diseases

Name	Disease Type	Mondoid

Pathway

Data Source	Name	Explore more targets	Explore in Source

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