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Targets(Human)
SLC6A5

SLC6A5

Description	Sodium- and chloride-dependent glycine transporter 2

Gene and Protein Information

Gene ID	9152
Uniprot Accession IDs	Q9Y345 O95288 Q4VAM7 Q9BX77 GlyT-2
Ensembl ID	ENSP00000434364
Symbol	GLYT2 NET1 NET1 GLYT2 HKPX3 GLYT-2
Family	Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. SLC6A5 subfamily.
Sequence	MDCSAPKEMNKLPANSPEAAAAQGHPDGPCAPRTSPEQELPAAAAPPPPRVPRSASTGAQTFQSADARACEAERPGVGSCKLSSPRAQAASAALRDLREAQGAQASPPPGSSGPGNALHCKIPFLRGPEGDANVSVGKGTLERNNTPVVGWVNMSQSTVVLATDGITSVLPGSVATVATQEDEQGDENKARGNWSSKLDFILSMVGYAVGLGNVWRFPYLAFQNGGGAFLIPYLMMLALAGLPIFFLEVSLGQFASQGPVSVWKAIPALQGCGIAMLIISVLIAIYYNVIICYTLFYLFASFVSVLPWGSCNNPWNTPECKDKTKLLLDSCVISDHPKIQIKNSTFCMTAYPNVTMVNFTSQANKTFVSGSEEYFKYFVLKISAGIEYPGEIRWPLALCLFLAWVIVYASLAKGIKTSGKVVYFTATFPYVVLVILLIRGVTLPGAGAGIWYFITPKWEKLTDATVWKDAATQIFFSLSAAWGGLITLSSYNKFHNNCYRDTLIVTCTNSATSIFAGFVIFSVIGFMANERKVNIENVADQGPGIAFVVYPEALTRLPLSPFWAIIFFLMLLTLGLDTMFATIETIVTSISDEFPKYLRTHKPVFTLGCCICFFIMGFPMITQGGIYMFQLVDTYAASYALVIIAIFELVGISYVYGLQRFCEDIEMMIGFQPNIFWKVCWAFVTPTILTFILCFSFYQWEPMTYGSYRYPNWSMVLGWLMLACSVIWIPIMFVIKMHLAPGRFIERLKLVCSPQPDWGPFLAQHRGERYKNMIDPLGTSSLGLKLPVKDLELGTQC Show more

Homologous gene and protein info.

Species	Gene ID	Gene Symbol	Name	Tax ID	Other Gene ID	Sources
Chimp	466470	SLC6A5	solute carrier family 6 member 5	9598	VGNC:7745	OMA, EggNOG
Macaque	704703	SLC6A5	solute carrier family 6 member 5	9544		OMA, EggNOG
Mouse	104245	Slc6a5	solute carrier family 6 (neurotransmitter transporter, glycine), member 5	10090	MGI:105090	Inparanoid, OMA, EggNOG
Rat	171148	Slc6a5	solute carrier family 6 member 5	10116	RGD:621824	Inparanoid, OMA
Dog	612095	SLC6A5	solute carrier family 6 member 5	9615	VGNC:46466	Inparanoid, OMA, EggNOG
Horse	100057380	SLC6A5	solute carrier family 6 member 5	9796	VGNC:23262	Inparanoid, OMA, EggNOG
Cow		SLC6A5	solute carrier family 6 member 5 [Source:HGNC Symbol;Acc:HGNC:11051]	9913		OMA, EggNOG
Opossum	100030555	SLC6A5	solute carrier family 6 member 5	13616		Inparanoid, OMA, EggNOG
Chicken	422974	SLC6A5	solute carrier family 6 member 5	9031	CGNC:2862	Inparanoid, OMA
Anole lizard	100566982	slc6a5	solute carrier family 6 member 5	28377		Inparanoid, OMA
Xenopus	100495275	slc6a5	solute carrier family 6 member 5	8364	XB-GENE-993852	Inparanoid, OMA
Zebrafish	494450	slc6a5	solute carrier family 6 (neurotransmitter transporter), member 5	7955	ZDB-GENE-050105-2	Inparanoid, OMA

Protein Classes

PANTHER Classes
protein / transporter / cation transporter / Sodium- and chloride-dependent glycine transporter 2

DTO Classes
protein / Transporter / SLC superfamily of solute carriers / SLC6 neurotransmitter transporter family / Glycine transporter subfamily / Sodium- and chloride-dependent glycine transporter 2

Associated Recombinant Proteins

Name	Specification and purity	Expression system	Protein label	Availability	View Details

Associated Antibodies

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Name	Specifications	Species reactivity	Application	Availability	View Details

Related active small molecules

A total of 10 itemsPrev1NextTopage

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Associated Approved Drugs

Associated Active Ligands

Associated Diseases

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Name	Direct Associated Targets	Disease Type	Mondoid

Bibliography

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