SLC6A5

Description	Sodium- and chloride-dependent glycine transporter 2

Gene and Protein Information

Gene ID	9152
Uniprot Accession IDs	O95288 Q4VAM7 Q9BX77 GlyT-2
Ensembl ID	ENSP00000434364
Symbol	GLYT2 NET1 NET1 GLYT2 HKPX3 GLYT-2
Family	Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. SLC6A5 subfamily.
Sequence	MDCSAPKEMNKLPANSPEAAAAQGHPDGPCAPRTSPEQELPAAAAPPPPRVPRSASTGAQTFQSADARACEAERPGVGSCKLSSPRAQAASAALRDLREAQGAQASPPPGSSGPGNALHCKIPFLRGPEGDANVSVGKGTLERNNTPVVGWVNMSQSTVVLATDGITSVLPGSVATVATQEDEQGDENKARGNWSSKLDFILSMVGYAVGLGNVWRFPYLAFQNGGGAFLIPYLMMLALAGLPIFFLEVSLGQFASQGPVSVWKAIPALQGCGIAMLIISVLIAIYYNVIICYTLFYLFASFVSVLPWGSCNNPWNTPECKDKTKLLLDSCVISDHPKIQIKNSTFCMTAYPNVTMVNFTSQANKTFVSGSEEYFKYFVLKISAGIEYPGEIRWPLALCLFLAWVIVYASLAKGIKTSGKVVYFTATFPYVVLVILLIRGVTLPGAGAGIWYFITPKWEKLTDATVWKDAATQIFFSLSAAWGGLITLSSYNKFHNNCYRDTLIVTCTNSATSIFAGFVIFSVIGFMANERKVNIENVADQGPGIAFVVYPEALTRLPLSPFWAIIFFLMLLTLGLDTMFATIETIVTSISDEFPKYLRTHKPVFTLGCCICFFIMGFPMITQGGIYMFQLVDTYAASYALVIIAIFELVGISYVYGLQRFCEDIEMMIGFQPNIFWKVCWAFVTPTILTFILCFSFYQWEPMTYGSYRYPNWSMVLGWLMLACSVIWIPIMFVIKMHLAPGRFIERLKLVCSPQPDWGPFLAQHRGERYKNMIDPLGTSSLGLKLPVKDLELGTQC Show more

Homologous gene and protein info.

Species	Gene ID	Gene Symbol	Name	Tax ID	Other Gene ID	Sources
Chimp	466470	SLC6A5	solute carrier family 6 member 5	9598	VGNC:7745	OMA, EggNOG
Macaque	704703	SLC6A5	solute carrier family 6 member 5	9544		OMA, EggNOG
Mouse	104245	Slc6a5	solute carrier family 6 (neurotransmitter transporter, glycine), member 5	10090	MGI:105090	Inparanoid, OMA, EggNOG
Rat	171148	Slc6a5	solute carrier family 6 member 5	10116	RGD:621824	Inparanoid, OMA
Dog	612095	SLC6A5	solute carrier family 6 member 5	9615	VGNC:46466	Inparanoid, OMA, EggNOG
Horse	100057380	SLC6A5	solute carrier family 6 member 5	9796	VGNC:23262	Inparanoid, OMA, EggNOG
Cow		SLC6A5	solute carrier family 6 member 5 [Source:HGNC Symbol;Acc:HGNC:11051]	9913		OMA, EggNOG
Opossum	100030555	SLC6A5	solute carrier family 6 member 5	13616		Inparanoid, OMA, EggNOG
Chicken	422974	SLC6A5	solute carrier family 6 member 5	9031	CGNC:2862	Inparanoid, OMA
Anole lizard	100566982	slc6a5	solute carrier family 6 member 5	28377		Inparanoid, OMA
Xenopus	100495275	slc6a5	solute carrier family 6 member 5	8364	XB-GENE-993852	Inparanoid, OMA
Zebrafish	494450	slc6a5	solute carrier family 6 (neurotransmitter transporter), member 5	7955	ZDB-GENE-050105-2	Inparanoid, OMA

Protein Classes

PANTHER Classes
protein / transporter / cation transporter / Sodium- and chloride-dependent glycine transporter 2

DTO Classes
protein / Transporter / SLC superfamily of solute carriers / SLC6 neurotransmitter transporter family / Glycine transporter subfamily / Sodium- and chloride-dependent glycine transporter 2

Associated Recombinant Proteins

Name	Specification and purity	Expression system	Protein label	Activity	View Details

Associated Antibodies

Name	Specifications	Species reactivity	species	Application	View Details

Associated Approved Drugs

Associated Active Ligands

Associated Diseases

Name	Disease Type	Mondoid

Pathway

Data Source	Name	Explore more targets	Explore in Source

🔙[Back to Target (Human)]