SCN4A
| Description | Sodium channel protein type 4 subunit alpha |
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Gene and Protein Information
| Gene ID | 6329 |
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| Uniprot Accession IDs | Q15478 Q16447 Q7Z6B1 |
| Ensembl ID | ENSP00000396320 |
| Symbol | HYPP SkM1 CMS16 HYKPP NAC1A HOKPP2 Nav1.4 Na(V)1.4 |
| Family | Belongs to the sodium channel (TC 1.A.1.10) family. Nav1.4/SCN4A subfamily. |
| Sequence | MARPSLCTLVPLGPECLRPFTRESLAAIEQRAVEEEARLQRNKQMEIEEPERKPRSDLEAGKNLPMIYGDPPPEVIGIPLEDLDPYYSNKKTFIVLNKGKAIFRFSATPALYLLSPFSVVRRGAIKVLIHALFSMFIMITILTNCVFMTMSDPPPWSKNVEYTFTGIYTFESLIKILARGFCVDDFTFLRDPWNWLDFSVIMMAYLTEFVDLGNISALRTFRVLRALKTITVIPGLKTIVGALIQSVKKLSDVMILTVFCLSVFALVGLQLFMGNLRQKCVRWPPPFNDTNTTWYSNDTWYGNDTWYGNEMWYGNDSWYANDTWNSHASWATNDTFDWDAYISDEGNFYFLEGSNDALLCGNSSDAGHCPEGYECIKTGRNPNYGYTSYDTFSWAFLALFRLMTQDYWENLFQLTLRAAGKTYMIFFVVIIFLGSFYLINLILAVVAMAYAEQNEATLAEDKEKEEEFQQMLEKFKKHQEELEKAKAAQALEGGEADGDPAHGKDCNGSLDTSQGEKGAPRQSSSGDSGISDAMEELEEAHQKCPPWWYKCAHKVLIWNCCAPWLKFKNIIHLIVMDPFVDLGITICIVLNTLFMAMEHYPMTEHFDNVLTVGNLVFTGIFTAEMVLKLIAMDPYEYFQQGWNIFDSIIVTLSLVELGLANVQGLSVLRSFRLLRVFKLAKSWPTLNMLIKIIGNSVGALGNLTLVLAIIVFIFAVVGMQLFGKSYKECVCKIALDCNLPRWHMHDFFHSFLIVFRILCGEWIETMWDCMEVAGQAMCLTVFLMVMVIGNLVVLNLFLALLLSSFSADSLAASDEDGEMNNLQIAIGRIKLGIGFAKAFLLGLLHGKILSPKDIMLSLGEADGAGEAGEAGETAPEDEKKEPPEEDLKKDNHILNHMGLADGPPSSLELDHLNFINNPYLTIQVPIASEESDLEMPTEEETDTFSEPEDSKKPPQPLYDGNSSVCSTADYKPPEEDPEEQAEENPEGEQPEECFTEACVQRWPCLYVDISQGRGKKWWTLRRACFKIVEHNWFETFIVFMILLSSGALAFEDIYIEQRRVIRTILEYADKVFTYIFIMEMLLKWVAYGFKVYFTNAWCWLDFLIVDVSIISLVANWLGYSELGPIKSLRTLRALRPLRALSRFEGMRVVVNALLGAIPSIMNVLLVCLIFWLIFSIMGVNLFAGKFYYCINTTTSERFDISEVNNKSECESLMHTGQVRWLNVKVNYDNVGLGYLSLLQVATFKGWMDIMYAAVDSREKEEQPQYEVNLYMYLYFVIFIIFGSFFTLNLFIGVIIDNFNQQKKKLGGKDIFMTEEQKKYYNAMKKLGSKKPQKPIPRPQNKIQGMVYDLVTKQAFDITIMILICLNMVTMMVETDNQSQLKVDILYNINMIFIIIFTGECVLKMLALRQYYFTVGWNIFDFVVVILSIVGLALSDLIQKYFVSPTLFRVIRLARIGRVLRLIRGAKGIRTLLFALMMSLPALFNIGLLLFLVMFIYSIFGMSNFAYVKKESGIDDMFNFETFGNSIICLFEITTSAGWDGLLNPILNSGPPDCDPNLENPGTSVKGDCGNPSIGICFFCSYIIISFLIVVNMYIAIILENFNVATEESSEPLGEDDFEMFYETWEKFDPDATQFIAYSRLSDFVDTLQEPLRIAKPNKIKLITLDLPMVPGDKIHCLDILFALTKEVLGDSGEMDALKQTMEEKFMAANPSKVSYEPITTTLKRKHEEVCAIKIQRAYRRHLLQRSMKQASYMYRHSHDGSGDDAPEKEGLLANTMSKMYGHENGNSSSPSPEEKGEAGDAGPTMGLMPISPSDTAWPPAPPPGQTVRPGVKESLV Show more |
Homologous gene and protein info.
| Species | Gene ID | Gene Symbol | Name | Tax ID | Other Gene ID | Sources |
|---|---|---|---|---|---|---|
| Chimp | 100612017 | SCN4A | sodium voltage-gated channel alpha subunit 4 | 9598 | VGNC:12667 | Inparanoid, OMA |
| Macaque | 718194 | SCN4A | sodium voltage-gated channel alpha subunit 4 | 9544 | Inparanoid, OMA | |
| Mouse | 110880 | Scn4a | sodium channel, voltage-gated, type IV, alpha | 10090 | MGI:98250 | Inparanoid, OMA, EggNOG |
| Rat | 25722 | Scn4a | sodium voltage-gated channel alpha subunit 4 | 10116 | RGD:3636 | Inparanoid, OMA, EggNOG |
| Dog | 610754 | SCN4A | sodium voltage-gated channel alpha subunit 4 | 9615 | VGNC:45920 | Inparanoid, OMA |
| Horse | 100049793 | SCN4A | sodium voltage-gated channel alpha subunit 4 | 9796 | VGNC:22738 | Inparanoid, OMA |
| Opossum | SCN4A | sodium voltage-gated channel alpha subunit 4 [Source:HGNC Symbol;Acc:HGNC:10591] | 13616 | Inparanoid, OMA | ||
| Anole lizard | 100555864 | scn4a | sodium voltage-gated channel alpha subunit 4 | 28377 | Inparanoid, OMA, EggNOG |
Protein Classes
PANTHER Classes
protein / transporter / calcium channel / Sodium channel protein type 4 subunit alpha
protein / transporter / voltage-gated sodium channel / Sodium channel protein type 4 subunit alpha
protein / transporter / voltage-gated calcium channel / Sodium channel protein type 4 subunit alpha
protein / transporter / sodium channel / Sodium channel protein type 4 subunit alpha
protein / transporter / voltage-gated ion channel / Sodium channel protein type 4 subunit alpha
protein / transporter / calcium channel / Sodium channel protein type 4 subunit alpha
protein / transporter / voltage-gated sodium channel / Sodium channel protein type 4 subunit alpha
protein / transporter / voltage-gated calcium channel / Sodium channel protein type 4 subunit alpha
protein / transporter / sodium channel / Sodium channel protein type 4 subunit alpha
protein / transporter / voltage-gated ion channel / Sodium channel protein type 4 subunit alpha
DTO Classes
protein / Ion channel / Sodium channel family / Nav1.4/SCN4A subfamily / Sodium channel protein type 4 subunit alpha
protein / Ion channel / Sodium channel family / Nav1.4/SCN4A subfamily / Sodium channel protein type 4 subunit alpha
Associated Recombinant Proteins
| Name | Specification and purity | Expression system | Protein label | Activity | View Details |
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Associated Antibodies
| Name | Specifications | Species reactivity | species | Application | View Details |
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Associated Approved Drugs
Associated Active Ligands
Associated Diseases
| Name | Disease Type | Mondoid |
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Pathway
| Data Source | Name | Explore more targets | Explore in Source |
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