Protein or Target Summary
Sodium channel protein type 8 subunit alpha
| Gene ID | 6334 |
|---|---|
| uniprot | Q9UQD0 |
| Gene Name | SCN8A |
| Ensernbl ID | ENSP00000346534 |
| Family | Belongs to the sodium channel (TC 1.A.1.10) family. Nav1.6/SCN8A subfamily. |
| Sequence | MAARLLAPPGPDSFKPFTPESLANIERRIAESKLKKPPKADGSHREDDEDSKPKPNSDLEAGKSLPFIYGDIPQGLVAVPLEDFDPYYLTQKTFVVLNRGKTLFRFSATPALYILSPFNLIRRIAIKILIHSVFSMIIMCTILTNCVFMTFSNPPDWSKNVEYTFTGIYTFESLVKIIARGFCIDGFTFLRDPWNWLDFSVIMMAYITEFVNLGNVSALRTFRVLRALKTISVIPGLKTIVGALIQSVKKLSDVMILTVFCLSVFALIGLQLFMGNLRNKCVVWPINFNESYLENGTKGFDWEEYINNKTNFYTVPGMLEPLLCGNSSDAGQCPEGYQCMKAGRNPNYGYTSFDTFSWAFLALFRLMTQDYWENLYQLTLRAAGKTYMIFFVLVIFVGSFYLVNLILAVVAMAYEEQNQATLEEAEQKEAEFKAMLEQLKKQQEEAQAAAMATSAGTVSEDAIEEEGEEGGGSPRSSSEISKLSSKSAKERRNRRKKRKQKELSEGEEKGDPEKVFKSESEDGMRRKAFRLPDNRIGRKFSIMNQSLLSIPGSPFLSRHNSKSSIFSFRGPGRFRDPGSENEFADDEHSTVEESEGRRDSLFIPIRARERRSSYSGYSGYSQGSRSSRIFPSLRRSVKRNSTVDCNGVVSLIGGPGSHIGGRLLPEATTEVEIKKKGPGSLLVSMDQLASYGRKDRINSIMSVVTNTLVEELEESQRKCPPCWYKFANTFLIWECHPYWIKLKEIVNLIVMDPFVDLAITICIVLNTLFMAMEHHPMTPQFEHVLAVGNLVFTGIFTAEMFLKLIAMDPYYYFQEGWNIFDGFIVSLSLMELSLADVEGLSVLRSFRLLRVFKLAKSWPTLNMLIKIIGNSVGALGNLTLVLAIIVFIFAVVGMQLFGKSYKECVCKINQDCELPRWHMHDFFHSFLIVFRVLCGEWIETMWDCMEVAGQAMCLIVFMMVMVIGNLVVLNLFLALLLSSFSADNLAATDDDGEMNNLQISVIRIKKGVAWTKLKVHAFMQAHFKQREADEVKPLDELYEKKANCIANHTGADIHRNGDFQKNGNGTTSGIGSSVEKYIIDEDHMSFINNPNLTVRVPIAVGESDFENLNTEDVSSESDPEGSKDKLDDTSSSEGSTIDIKPEVEEVPVEQPEEYLDPDACFTEGCVQRFKCCQVNIEEGLGKSWWILRKTCFLIVEHNWFETFIIFMILLSSGALAFEDIYIEQRKTIRTILEYADKVFTYIFILEMLLKWTAYGFVKFFTNAWCWLDFLIVAVSLVSLIANALGYSELGAIKSLRTLRALRPLRALSRFEGMRVVVNALVGAIPSIMNVLLVCLIFWLIFSIMGVNLFAGKYHYCFNETSEIRFEIEDVNNKTECEKLMEGNNTEIRWKNVKINFDNVGAGYLALLQVATFKGWMDIMYAAVDSRKPDEQPKYEDNIYMYIYFVIFIIFGSFFTLNLFIGVIIDNFNQQKKKFGGQDIFMTEEQKKYYNAMKKLGSKKPQKPIPRPLNKIQGIVFDFVTQQAFDIVIMMLICLNMVTMMVETDTQSKQMENILYWINLVFVIFFTCECVLKMFALRHYYFTIGWNIFDFVVVILSIVGMFLADIIEKYFVSPTLFRVIRLARIGRILRLIKGAKGIRTLLFALMMSLPALFNIGLLLFLVMFIFSIFGMSNFAYVKHEAGIDDMFNFETFGNSMICLFQITTSAGWDGLLLPILNRPPDCSLDKEHPGSGFKGDCGNPSVGIFFFVSYIIISFLIVVNMYIAIILENFSVATEESADPLSEDDFETFYEIWEKFDPDATQFIEYCKLADFADALEHPLRVPKPNTIELIAMDLPMVSGDRIHCLDILFAFTKRVLGDSGELDILRQQMEERFVASNPSKVSYEPITTTLRRKQEEVSAVVLQRAYRGHLARRGFICKKTTSNKLENGGTHREKKESTPSTASLPSYDSVTKPEKEKQQRAEEGRRERAKRQKEVRESKC Show more |
Gene and Protein Information
| Species | Gene ID | Gene Symbol | Gene Name | Uniprot |
|---|---|---|---|---|
| HUMAN | 6334 | SCN8A | Sodium channel protein type 8 subunit alpha | Q9UQD0 |
| MOUSE | 20273 | Scn8a | Sodium channel protein | A0A0R5RP22 |
| MOUSE | 20273 | Scn8a | Sodium channel protein | F7D6J5 |
| MOUSE | Scn8a | Sodium channel protein type 8 subunit alpha | A0A0J9YUK3 | |
| MOUSE | Scn8a | Sodium channel protein type 8 subunit alpha | A0A0J9YTW2 | |
| MOUSE | Scn8a | Sodium channel protein type 8 subunit alpha | A0A0J9YUL0 | |
| MOUSE | Scn8a | Truncated voltage-gated sodium channel alpha subunit | O35953 | |
| MOUSE | 20273 | Scn8a | Sodium channel protein | A0A0J9YUW5 |
| MOUSE | Scn8a | Sodium channel protein type 8 subunit alpha | A0A0J9YTW4 | |
| MOUSE | Scn8a | Scn8a protein | Q4KL32 | |
| MOUSE | 20273 | Scn8a | Sodium channel protein | F6U329 |
| MOUSE | 20273 | Scn8a | Sodium channel protein | F7D6K4 |
| MOUSE | 20273 | Scn8a | Sodium channel protein type 8 subunit alpha | Q9WTU3 |
| RAT | Scn8a | Sodium channel protein | F1LMH2 | |
| RAT | Scn8a | Sodium channel protein | A0A0G2KB93 | |
| RAT | 29710 | Scn8a | Sodium channel protein type 8 subunit alpha | O88420 |
Protein Classes
PANTHER Classes
protein / transporter / calcium channel / Sodium channel protein type 8 subunit alpha
protein / transporter / voltage-gated sodium channel / Sodium channel protein type 8 subunit alpha
protein / transporter / voltage-gated calcium channel / Sodium channel protein type 8 subunit alpha
protein / transporter / sodium channel / Sodium channel protein type 8 subunit alpha
protein / transporter / voltage-gated ion channel / Sodium channel protein type 8 subunit alpha
protein / transporter / calcium channel / Sodium channel protein type 8 subunit alpha
protein / transporter / voltage-gated sodium channel / Sodium channel protein type 8 subunit alpha
protein / transporter / voltage-gated calcium channel / Sodium channel protein type 8 subunit alpha
protein / transporter / sodium channel / Sodium channel protein type 8 subunit alpha
protein / transporter / voltage-gated ion channel / Sodium channel protein type 8 subunit alpha
DTO Classes
protein / Ion channel / Sodium channel family / Nav1.6/SCN8A subfamily / Sodium channel protein type 8 subunit alpha
protein / Ion channel / Sodium channel family / Nav1.6/SCN8A subfamily / Sodium channel protein type 8 subunit alpha
Associated Recombinant Proteins
| Name | Specification and purity | Expression system | Protein label | Activity | View Details |
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Associated Antibodies
| Name | Specifications | Species reactivity | species | Application | View Details |
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Associated Approved Drugs
Associated Active Ligands
Associated Diseases
| Name | Disease Type | Mondoid |
|---|
Pathway
| Data Source | Name | Explore more targets | Explore in Source |
|---|
Source: DataSourcesLicenses.xlsx