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Protein or Target Summary

Sodium- and chloride-dependent GABA transporter 1

Gene ID6529
uniprotP30531
Gene NameSLC6A1
Ensernbl IDENSP00000287766
FamilyBelongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. SLC6A1 subfamily.
Sequence
MATNGSKVADGQISTEVSEAPVANDKPKTLVVKVQKKAADLPDRDTWKGRFDFLMSCVGYAIGLGNVWRFPYLCGKNGGGAFLIPYFLTLIFAGVPLFLLECSLGQYTSIGGLGVWKLAPMFKGVGLAAAVLSFWLNIYYIVIISWAIYYLYNSFTTTLPWKQCDNPWNTDRCFSNYSMVNTTNMTSAVVEFWERNMHQMTDGLDKPGQIRWPLAITLAIAWILVYFCIWKGVGWTGKVVYFSATYPYIMLIILFFRGVTLPGAKEGILFYITPNFRKLSDSEVWLDAATQIFFSYGLGLGSLIALGSYNSFHNNVYRDSIIVCCINSCTSMFAGFVIFSIVGFMAHVTKRSIADVAASGPGLAFLAYPEAVTQLPISPLWAILFFSMLLMLGIDSQFCTVEGFITALVDEYPRLLRNRRELFIAAVCIISYLIGLSNITQGGIYVFKLFDYYSASGMSLLFLVFFECVSISWFYGVNRFYDNIQEMVGSRPCIWWKLCWSFFTPIIVAGVFIFSAVQMTPLTMGNYVFPKWGQGVGWLMALSSMVLIPGYMAYMFLTLKGSLKQRIQVMVQPSEDIVRPENGPEQPQAGSSTSKEAYI
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Gene and Protein Information

SpeciesGene IDGene SymbolGene NameUniprot
HUMAN6529SLC6A1Sodium- and chloride-dependent GABA transporter 1P30531
MOUSESlc6a1Sodium- and chloride-dependent GABA transporter 1A0A0N4SVF5
MOUSE232333Slc6a1TransporterQ6PCX2
MOUSE232333Slc6a1Sodium- and chloride-dependent GABA transporter 1P31648
RAT79212Slc6a1Sodium- and chloride-dependent GABA transporter 1P23978

Protein Classes

PANTHER Classes
protein    /    transporter    /    cation transporter    /    Sodium- and chloride-dependent GABA transporter 1
DTO Classes
protein    /    Transporter    /    SLC superfamily of solute carriers    /    SLC6 neurotransmitter transporter family    /    GABA transporter subfamily    /    Sodium- and chloride-dependent GABA transporter 1

Associated Recombinant Proteins

NameSpecification and purityExpression systemProtein labelActivityView Details

Associated Antibodies

NameSpecificationsSpecies reactivityspeciesApplicationView Details

Associated Approved Drugs

    Associated Active Ligands

      Associated Diseases

      NameDisease TypeMondoid

      Pathway

      Data SourceNameExplore more targetsExplore in Source