SLC6A1

Description	Sodium- and chloride-dependent GABA transporter 1

Gene and Protein Information

Gene ID	6529
Uniprot Accession IDs	Q8N4K8 GAT-1
Ensembl ID	ENSP00000287766
Symbol	GABATR GABT1 GAT1 MAE GAT1 GABATR GABATHG
Family	Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. SLC6A1 subfamily.
Sequence	MATNGSKVADGQISTEVSEAPVANDKPKTLVVKVQKKAADLPDRDTWKGRFDFLMSCVGYAIGLGNVWRFPYLCGKNGGGAFLIPYFLTLIFAGVPLFLLECSLGQYTSIGGLGVWKLAPMFKGVGLAAAVLSFWLNIYYIVIISWAIYYLYNSFTTTLPWKQCDNPWNTDRCFSNYSMVNTTNMTSAVVEFWERNMHQMTDGLDKPGQIRWPLAITLAIAWILVYFCIWKGVGWTGKVVYFSATYPYIMLIILFFRGVTLPGAKEGILFYITPNFRKLSDSEVWLDAATQIFFSYGLGLGSLIALGSYNSFHNNVYRDSIIVCCINSCTSMFAGFVIFSIVGFMAHVTKRSIADVAASGPGLAFLAYPEAVTQLPISPLWAILFFSMLLMLGIDSQFCTVEGFITALVDEYPRLLRNRRELFIAAVCIISYLIGLSNITQGGIYVFKLFDYYSASGMSLLFLVFFECVSISWFYGVNRFYDNIQEMVGSRPCIWWKLCWSFFTPIIVAGVFIFSAVQMTPLTMGNYVFPKWGQGVGWLMALSSMVLIPGYMAYMFLTLKGSLKQRIQVMVQPSEDIVRPENGPEQPQAGSSTSKEAYI Show more

Homologous gene and protein info.

Species	Gene ID	Gene Symbol	Name	Tax ID	Other Gene ID	Sources
Chimp	460170	SLC6A1	solute carrier family 6 member 1	9598	VGNC:8856	OMA, EggNOG
Macaque	696617	SLC6A1	solute carrier family 6 member 1	9544		Inparanoid, OMA, EggNOG
Mouse	232333	Slc6a1	solute carrier family 6 (neurotransmitter transporter, GABA), member 1	10090	MGI:95627	Inparanoid, OMA, EggNOG
Rat	79212	Slc6a1	solute carrier family 6 member 1	10116	RGD:620533	Inparanoid, OMA, EggNOG
Dog	484655	SLC6A1	solute carrier family 6 member 1	9615	VGNC:46453	Inparanoid, OMA, EggNOG
Horse	100051613	SLC6A1	solute carrier family 6 member 1	9796	VGNC:23251	Inparanoid, OMA, EggNOG
Cow	407118	SLC6A1	solute carrier family 6 member 1	9913	VGNC:34913	Inparanoid, OMA, EggNOG
Pig	100156668	SLC6A1	solute carrier family 6 member 1	9823		Inparanoid, OMA, EggNOG
Opossum	100015027	SLC6A1	solute carrier family 6 member 1	13616		Inparanoid, OMA, EggNOG
Chicken	415960	SLC6A1	solute carrier family 6 member 1	9031	CGNC:3654	Inparanoid, OMA
Anole lizard	100556107	slc6a1	solute carrier family 6 member 1	28377		Inparanoid, OMA, EggNOG
Xenopus		XB-GENE-5944458	hypothetical protein LOC100127682 [Source:Xenbase;Acc:XB-GENE-5944458]	8364		OMA, EggNOG
Zebrafish	492490	slc6a1b	solute carrier family 6 (neurotransmitter transporter), member 1b	7955	ZDB-GENE-041114-57	OMA, EggNOG
Zebrafish	692318	slc6a1a	solute carrier family 6 (neurotransmitter transporter), member 1a	7955	ZDB-GENE-060519-23	Inparanoid, OMA
C. elegans	191770	snf-11	Transporter	6239		Inparanoid, OMA

Protein Classes

PANTHER Classes
protein / transporter / cation transporter / Sodium- and chloride-dependent GABA transporter 1

DTO Classes
protein / Transporter / SLC superfamily of solute carriers / SLC6 neurotransmitter transporter family / GABA transporter subfamily / Sodium- and chloride-dependent GABA transporter 1

Associated Recombinant Proteins

Name	Specification and purity	Expression system	Protein label	Activity	View Details

Associated Antibodies

Name	Specifications	Species reactivity	species	Application	View Details

Associated Approved Drugs

Associated Active Ligands

Associated Diseases

Name	Disease Type	Mondoid

Pathway

Data Source	Name	Explore more targets	Explore in Source

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