TBK1

DescriptionSerine/threonine-protein kinase TBK1

Gene and Protein Information

Gene ID29110
Uniprot Accession IDs A8K4S4 Q8IYV3 Q9NUJ5
Ensembl ID ENSP00000329967
Symbol NAK NAK T2K IIAE8 FTDALS4
FamilyBelongs to the protein kinase superfamily. Ser/Thr protein kinase family. I-kappa-B kinase subfamily.
Sequence
MQSTSNHLWLLSDILGQGATANVFRGRHKKTGDLFAIKVFNNISFLRPVDVQMREFEVLKKLNHKNIVKLFAIEEETTTRHKVLIMEFCPCGSLYTVLEEPSNAYGLPESEFLIVLRDVVGGMNHLRENGIVHRDIKPGNIMRVIGEDGQSVYKLTDFGAARELEDDEQFVSLYGTEEYLHPDMYERAVLRKDHQKKYGATVDLWSIGVTFYHAATGSLPFRPFEGPRRNKEVMYKIITGKPSGAISGVQKAENGPIDWSGDMPVSCSLSRGLQVLLTPVLANILEADQEKCWGFDQFFAETSDILHRMVIHVFSLQQMTAHKIYIHSYNTATIFHELVYKQTKIISSNQELIYEGRRLVLEPGRLAQHFPKTTEENPIFVVSREPLNTIGLIYEKISLPKVHPRYDLDGDASMAKAITGVVCYACRIASTLLLYQELMRKGIRWLIELIKDDYNETVHKKTEVVITLDFCIRNIEKTVKVYEKLMKINLEAAELGEISDIHTKLLRLSSSQGTIETSLQDIDSRLSPGGSLADAWAHQEGTHPKDRNVEKLQVLLNCMTEIYYQFKKDKAERRLAYNEEQIHKFDKQKLYYHATKAMTHFTDECVKKYEAFLNKSEEWIRKMLHLRKQLLSLTNQCFDIEEEVSKYQEYTNELQETLPQKMFTASSGIKHTMTPIYPSSNTLVEMTLGMKKLKEEMEGVVKELAENNHILERFGSLTMDGGLRNVDCL
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Homologous gene and protein info.
SpeciesGene IDGene SymbolNameTax IDOther Gene IDSources
Chimp452047TBK1TANK binding kinase 19598VGNC:8581OMA, EggNOG
Macaque717427TBK1TANK binding kinase 19544Inparanoid, OMA, EggNOG
Mouse56480Tbk1TANK-binding kinase 110090MGI:1929658Inparanoid, OMA, EggNOG
Rat299827Tbk1TANK-binding kinase 110116RGD:1588588Inparanoid, OMA, EggNOG
Dog481145TBK1TANK binding kinase 19615VGNC:47160Inparanoid, OMA, EggNOG
Horse100051650TBK1TANK binding kinase 19796VGNC:23923Inparanoid, OMA, EggNOG
Cow533141TBK1TANK binding kinase 19913VGNC:35656Inparanoid, OMA, EggNOG
Platypus100076520TBK1TANK binding kinase 19258Inparanoid, OMA, EggNOG
Chicken417825TBK1TANK binding kinase 19031CGNC:7475Inparanoid, OMA
Anole lizard100553575tbk1TANK binding kinase 128377Inparanoid, OMA
Xenopus100216212tbk1TANK binding kinase 18364XB-GENE-955452Inparanoid, OMA

Protein Classes

PANTHER Classes
protein    /    non-receptor serine/threonine protein kinase    /    Serine/threonine-protein kinase tbk1
protein    /    protein kinase    /    Serine/threonine-protein kinase tbk1
protein    /    transferase    /    Serine/threonine-protein kinase tbk1
protein    /    kinase    /    Serine/threonine-protein kinase tbk1
DTO Classes
protein    /    Kinase    /    Protein kinase    /    Other group    /    IKK family    /    Serine/threonine-protein kinase tbk1

Associated Recombinant Proteins

NameSpecification and purityExpression systemProtein labelActivityView Details

Associated Antibodies

NameSpecificationsSpecies reactivityspeciesApplicationView Details

Associated Approved Drugs

    Associated Active Ligands

      Associated Diseases

      NameDisease TypeMondoid

      Pathway

      Data SourceNameExplore more targetsExplore in Source