Protein or Target Summary
Werner syndrome ATP-dependent helicase
| Gene ID | 7486 |
|---|---|
| uniprot | Q14191 |
| Gene Name | WRN |
| Ensernbl ID | ENSP00000298139 |
| Family | Belongs to the helicase family. RecQ subfamily. |
| Sequence | MSEKKLETTAQQRKCPEWMNVQNKRCAVEERKACVRKSVFEDDLPFLEFTGSIVYSYDASDCSFLSEDISMSLSDGDVVGFDMEWPPLYNRGKLGKVALIQLCVSESKCYLFHVSSMSVFPQGLKMLLENKAVKKAGVGIEGDQWKLLRDFDIKLKNFVELTDVANKKLKCTETWSLNSLVKHLLGKQLLKDKSIRCSNWSKFPLTEDQKLYAATDAYAGFIIYRNLEILDDTVQRFAINKEEEILLSDMNKQLTSISEEVMDLAKHLPHAFSKLENPRRVSILLKDISENLYSLRRMIIGSTNIETELRPSNNLNLLSFEDSTTGGVQQKQIREHEVLIHVEDETWDPTLDHLAKHDGEDVLGNKVERKEDGFEDGVEDNKLKENMERACLMSLDITEHELQILEQQSQEEYLSDIAYKSTEHLSPNDNENDTSYVIESDEDLEMEMLKHLSPNDNENDTSYVIESDEDLEMEMLKSLENLNSGTVEPTHSKCLKMERNLGLPTKEEEEDDENEANEGEEDDDKDFLWPAPNEEQVTCLKMYFGHSSFKPVQWKVIHSVLEERRDNVAVMATGYGKSLCFQYPPVYVGKIGLVISPLISLMEDQVLQLKMSNIPACFLGSAQSENVLTDIKLGKYRIVYVTPEYCSGNMGLLQQLEADIGITLIAVDEAHCISEWGHDFRDSFRKLGSLKTALPMVPIVALTATASSSIREDIVRCLNLRNPQITCTGFDRPNLYLEVRRKTGNILQDLQPFLVKTSSHWEFEGPTIIYCPSRKMTQQVTGELRKLNLSCGTYHAGMSFSTRKDIHHRFVRDEIQCVIATIAFGMGINKADIRQVIHYGAPKDMESYYQEIGRAGRDGLQSSCHVLWAPADINLNRHLLTEIRNEKFRLYKLKMMAKMEKYLHSSRCRRQIILSHFEDKQVQKASLGIMGTEKCCDNCRSRLDHCYSMDDSEDTSWDFGPQAFKLLSAVDILGEKFGIGLPILFLRGSNSQRLADQYRRHSLFGTGKDQTESWWKAFSRQLITEGFLVEVSRYNKFMKICALTKKGRNWLHKANTESQSLILQANEELCPKKLLLPSSKTVSSGTKEHCYNQVPVELSTEKKSNLEKLYSYKPCDKISSGSNISKKSIMVQSPEKAYSSSQPVISAQEQETQIVLYGKLVEARQKHANKMDVPPAILATNKILVDMAKMRPTTVENVKRIDGVSEGKAAMLAPLLEVIKHFCQTNSVQTDLFSSTKPQEEQKTSLVAKNKICTLSQSMAITYSLFQEKKMPLKSIAESRILPLMTIGMHLSQAVKAGCPLDLERAGLTPEVQKIIADVIRNPPVNSDMSKISLIRMLVPENIDTYLIHMAIEILKHGPDSGLQPSCDVNKRRCFPGSEEICSSSKRSKEEVGINTETSSAERKRRLPVWFAKGSDTSKKLMDKTKRGGLFS Show more |
Gene and Protein Information
| Species | Gene ID | Gene Symbol | Gene Name | Uniprot |
|---|---|---|---|---|
| HUMAN | 7486 | WRN | Werner syndrome ATP-dependent helicase | Q14191 |
| MOUSE | Wrn | Uncharacterized protein | Q3TZ13 | |
| MOUSE | Wrn | ATP-dependent DNA helicase | O35948 | |
| MOUSE | Wrn | Uncharacterized protein | Q3TMV6 | |
| MOUSE | 22427 | Wrn | Uncharacterized protein | Q3TB25 |
| MOUSE | 22427 | Wrn | Uncharacterized protein | Q8BWH5 |
| MOUSE | Wrn | Werner syndrome ATP-dependent helicase homolog | A0A1B0GR54 | |
| MOUSE | 22427 | Wrn | Werner syndrome ATP-dependent helicase homolog | O09053 |
| RAT | 290805 | Wrn | Werner syndrome RecQ-like helicase | F1LTH9 |
Protein Classes
PANTHER Classes
protein / nucleic acid binding / DNA binding protein / Werner syndrome ATP-dependent helicase
protein / nucleic acid binding / DNA helicase / Werner syndrome ATP-dependent helicase
protein / nucleic acid binding / helicase / Werner syndrome ATP-dependent helicase
protein / nucleic acid binding / DNA binding protein / Werner syndrome ATP-dependent helicase
protein / nucleic acid binding / DNA helicase / Werner syndrome ATP-dependent helicase
protein / nucleic acid binding / helicase / Werner syndrome ATP-dependent helicase
Associated Recombinant Proteins
| Name | Specification and purity | Expression system | Protein label | Activity | View Details |
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Associated Antibodies
| Name | Specifications | Species reactivity | species | Application | View Details |
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Associated Approved Drugs
Associated Active Ligands
Associated Diseases
| Name | Disease Type | Mondoid |
|---|
Pathway
| Data Source | Name | Explore more targets | Explore in Source |
|---|
Source: DataSourcesLicenses.xlsx