TGFBR1
| Description | TGF-beta receptor type-1 |
|---|
Gene and Protein Information
| Gene ID | 7046 |
|---|---|
| Uniprot Accession IDs | Q6IR47 Q706C0 Q706C1 TGFR-1 |
| Ensembl ID | ENSP00000364133 |
| Symbol | ALK5 SKR4 AAT5 ALK5 ESS1 LDS1 MSSE SKR4 TBRI ALK-5 LDS1A LDS2A TBR-i TGFR-1 ACVRLK4 tbetaR-I |
| Family | Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. |
| Sequence | MEAAVAAPRPRLLLLVLAAAAAAAAALLPGATALQCFCHLCTKDNFTCVTDGLCFVSVTETTDKVIHNSMCIAEIDLIPRDRPFVCAPSSKTGSVTTTYCCNQDHCNKIELPTTVKSSPGLGPVELAAVIAGPVCFVCISLMLMVYICHNRTVIHHRVPNEEDPSLDRPFISEGTTLKDLIYDMTTSGSGSGLPLLVQRTIARTIVLQESIGKGRFGEVWRGKWRGEEVAVKIFSSREERSWFREAEIYQTVMLRHENILGFIAADNKDNGTWTQLWLVSDYHEHGSLFDYLNRYTVTVEGMIKLALSTASGLAHLHMEIVGTQGKPAIAHRDLKSKNILVKKNGTCCIADLGLAVRHDSATDTIDIAPNHRVGTKRYMAPEVLDDSINMKHFESFKRADIYAMGLVFWEIARRCSIGGIHEDYQLPYYDLVPSDPSVEEMRKVVCEQKLRPNIPNRWQSCEALRVMAKIMRECWYANGAARLTALRIKKTLSQLSQQEGIKM Show more |
Homologous gene and protein info.
| Species | Gene ID | Gene Symbol | Name | Tax ID | Other Gene ID | Sources |
|---|---|---|---|---|---|---|
| Chimp | 472992 | TGFBR1 | transforming growth factor beta receptor 1 | 9598 | VGNC:4876 | OMA, EggNOG |
| Macaque | 714952 | TGFBR1 | transforming growth factor beta receptor 1 | 9544 | Inparanoid, OMA, EggNOG | |
| Mouse | 21812 | Tgfbr1 | transforming growth factor, beta receptor I | 10090 | MGI:98728 | Inparanoid, OMA, EggNOG |
| Rat | 29591 | Tgfbr1 | transforming growth factor, beta receptor 1 | 10116 | RGD:3852 | Inparanoid, EggNOG |
| Dog | 481628 | TGFBR1 | transforming growth factor beta receptor 1 | 9615 | VGNC:51764 | Inparanoid, OMA, EggNOG |
| Horse | 100034117 | TGFBR1 | transforming growth factor beta receptor 1 | 9796 | VGNC:49281 | Inparanoid, OMA, EggNOG |
| Cow | 282382 | TGFBR1 | transforming growth factor beta receptor 1 | 9913 | VGNC:35804 | Inparanoid, OMA, EggNOG |
| Opossum | 100011507 | TGFBR1 | transforming growth factor beta receptor 1 | 13616 | Inparanoid, OMA, EggNOG | |
| Platypus | TGFBR1 | transforming growth factor beta receptor 1 [Source:HGNC Symbol;Acc:HGNC:11772] | 9258 | OMA, EggNOG | ||
| Anole lizard | 100566944 | tgfbr1 | transforming growth factor beta receptor 1 | 28377 | Inparanoid, OMA, EggNOG | |
| Xenopus | 548715 | tgfbr1 | transforming growth factor beta receptor I | 8364 | XB-GENE-478587 | Inparanoid, OMA, EggNOG |
| Zebrafish | 792928 | tgfbr1b | transforming growth factor, beta receptor 1 b | 7955 | ZDB-GENE-091027-1 | Inparanoid, OMA |
Protein Classes
PANTHER Classes
protein / receptor / protein kinase receptor / Tgf-beta receptor type-1
protein / receptor / TGF-beta receptor / Tgf-beta receptor type-1
protein / receptor / serine/threonine protein kinase receptor / Tgf-beta receptor type-1
protein / receptor / protein kinase / Tgf-beta receptor type-1
protein / receptor / transferase / Tgf-beta receptor type-1
protein / receptor / kinase / Tgf-beta receptor type-1
protein / receptor / protein kinase receptor / Tgf-beta receptor type-1
protein / receptor / TGF-beta receptor / Tgf-beta receptor type-1
protein / receptor / serine/threonine protein kinase receptor / Tgf-beta receptor type-1
protein / receptor / protein kinase / Tgf-beta receptor type-1
protein / receptor / transferase / Tgf-beta receptor type-1
protein / receptor / kinase / Tgf-beta receptor type-1
DTO Classes
protein / Kinase / Protein kinase / TKL group / STKR family / STKR Type 1 subfamily / Tgf-beta receptor type-1
protein / Kinase / Protein kinase / TKL group / STKR family / STKR Type 1 subfamily / Tgf-beta receptor type-1
Associated Recombinant Proteins
| Name | Specification and purity | Expression system | Protein label | Activity | View Details |
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Associated Antibodies
| Name | Specifications | Species reactivity | species | Application | View Details |
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Associated Approved Drugs
Associated Active Ligands
Associated Diseases
| Name | Disease Type | Mondoid |
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Pathway
| Data Source | Name | Explore more targets | Explore in Source |
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