MPL

DescriptionThrombopoietin receptor

Gene and Protein Information

Gene ID4352
Uniprot Accession IDs Q5JUZ0 TPO-R
Ensembl ID ENSP00000361548
Symbol TPOR MPLV TPOR C-MPL CD110 THPOR THCYT2
FamilyBelongs to the type I cytokine receptor family. Type 1 subfamily.
Sequence
MPSWALFMVTSCLLLAPQNLAQVSSQDVSLLASDSEPLKCFSRTFEDLTCFWDEEEAAPSGTYQLLYAYPREKPRACPLSSQSMPHFGTRYVCQFPDQEEVRLFFPLHLWVKNVFLNQTRTQRVLFVDSVGLPAPPSIIKAMGGSQPGELQISWEEPAPEISDFLRYELRYGPRDPKNSTGPTVIQLIATETCCPALQRPHSASALDQSPCAQPTMPWQDGPKQTSPSREASALTAEGGSCLISGLQPGNSYWLQLRSEPDGISLGGSWGSWSLPVTVDLPGDAVALGLQCFTLDLKNVTCQWQQQDHASSQGFFYHSRARCCPRDRYPIWENCEEEEKTNPGLQTPQFSRCHFKSRNDSIIHILVEVTTAPGTVHSYLGSPFWIHQAVRLPTPNLHWREISSGHLELEWQHPSSWAAQETCYQLRYTGEGHQDWKVLEPPLGARGGTLELRPRSRYRLQLRARLNGPTYQGPWSSWSDPTRVETATETAWISLVTALHLVLGLSAVLGLLLLRWQFPAHYRRLRHALWPSLPDLHRVLGQYLRDTAALSPPKATVSDTCEEVEPSLLEILPKSSERTPLPLCSSQAQMDYRRLQPSCLGTMPLSVCPPMAESGSCCTTHIANHSYLPLSYWQQP
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Homologous gene and protein info.
SpeciesGene IDGene SymbolNameTax IDOther Gene IDSources
Macaque723813MPLMPL proto-oncogene, thrombopoietin receptor9544OMA, EggNOG
Mouse17480Mplmyeloproliferative leukemia virus oncogene10090MGI:97076Inparanoid, OMA, EggNOG
Rat366455MplMPL proto-oncogene, thrombopoietin receptor10116RGD:1311069Inparanoid, OMA, EggNOG
Dog610801MPLMPL proto-oncogene, thrombopoietin receptor9615VGNC:43338Inparanoid, OMA, EggNOG
Horse100066544MPLMPL proto-oncogene, thrombopoietin receptor9796VGNC:20287Inparanoid, OMA, EggNOG
Cow528492MPLMPL proto-oncogene, thrombopoietin receptor9913VGNC:31578Inparanoid, OMA, EggNOG
Pig100626347MPLMPL proto-oncogene, thrombopoietin receptor9823Inparanoid, EggNOG
Chicken414804MPLMPL proto-oncogene, thrombopoietin receptor9031CGNC:7572Inparanoid, OMA
Zebrafish445381mplMPL proto-oncogene, thrombopoietin receptor7955ZDB-GENE-060421-1Inparanoid, OMA, EggNOG

Protein Classes

PANTHER Classes
protein    /    receptor    /    type I cytokine receptor    /    Thrombopoietin receptor
DTO Classes
protein    /    Receptor    /    Cytokine receptor    /    Type I cytokine receptor    /    Thrombopoietin receptor

Associated Recombinant Proteins

NameSpecification and purityExpression systemProtein labelActivityView Details

Associated Antibodies

NameSpecificationsSpecies reactivityspeciesApplicationView Details

Associated Approved Drugs

    Associated Active Ligands

      Associated Diseases

      NameDisease TypeMondoid

      Pathway

      Data SourceNameExplore more targetsExplore in Source