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TLR4
| Description | Toll-like receptor 4 |
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Gene and Protein Information
| Gene ID | 7099 |
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| Uniprot Accession IDs | A8K1Y8 A9XLP9 A9XLQ0 A9XLQ1 B4E194 D1CS52 D1CS53 Q5VZI8 Q5VZI9 Q9UK78 Q9UM57 |
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| Ensembl ID | ENSP00000363089 |
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| Symbol | TOLL CD284 TLR-4 ARMD10 |
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| Family | Belongs to the Toll-like receptor family. |
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| Sequence | MMSASRLAGTLIPAMAFLSCVRPESWEPCVEVVPNITYQCMELNFYKIPDNLPFSTKNLDLSFNPLRHLGSYSFFSFPELQVLDLSRCEIQTIEDGAYQSLSHLSTLILTGNPIQSLALGAFSGLSSLQKLVAVETNLASLENFPIGHLKTLKELNVAHNLIQSFKLPEYFSNLTNLEHLDLSSNKIQSIYCTDLRVLHQMPLLNLSLDLSLNPMNFIQPGAFKEIRLHKLTLRNNFDSLNVMKTCIQGLAGLEVHRLVLGEFRNEGNLEKFDKSALEGLCNLTIEEFRLAYLDYYLDDIIDLFNCLTNVSSFSLVSVTIERVKDFSYNFGWQHLELVNCKFGQFPTLKLKSLKRLTFTSNKGGNAFSEVDLPSLEFLDLSRNGLSFKGCCSQSDFGTTSLKYLDLSFNGVITMSSNFLGLEQLEHLDFQHSNLKQMSEFSVFLSLRNLIYLDISHTHTRVAFNGIFNGLSSLEVLKMAGNSFQENFLPDIFTELRNLTFLDLSQCQLEQLSPTAFNSLSSLQVLNMSHNNFFSLDTFPYKCLNSLQVLDYSLNHIMTSKKQELQHFPSSLAFLNLTQNDFACTCEHQSFLQWIKDQRQLLVEVERMECATPSDKQGMPVLSLNITCQMNKTIIGVSVLSVLVVSVVAVLVYKFYFHLMLLAGCIKYGRGENIYDAFVIYSSQDEDWVRNELVKNLEEGVPPFQLCLHYRDFIPGVAIAANIIHEGFHKSRKVIVVVSQHFIQSRWCIFEYEIAQTWQFLSSRAGIIFIVLQKVEKTLLRQQVELYRLLSRNTYLEWEDSVLGRHIFWRRLRKALLDGKSWNPEGTVGTGCNWQEATSI Show more |
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Homologous gene and protein info.
| Species | Gene ID | Gene Symbol | Name | Tax ID | Other Gene ID | Sources |
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| Chimp | 743242 | TLR4 | toll like receptor 4 | 9598 | VGNC:13978 | Inparanoid, OMA, EggNOG |
| Macaque | 574360 | TLR4 | toll like receptor 4 | 9544 | | Inparanoid, OMA, EggNOG |
| Mouse | 21898 | Tlr4 | toll-like receptor 4 | 10090 | MGI:96824 | Inparanoid, OMA, EggNOG |
| Rat | 29260 | Tlr4 | toll-like receptor 4 | 10116 | RGD:3870 | Inparanoid, OMA, EggNOG |
| Dog | 403417 | TLR4 | toll like receptor 4 | 9615 | VGNC:51765 | Inparanoid, OMA, EggNOG |
| Horse | 100066890 | TLR4 | toll like receptor 4 | 9796 | | Inparanoid, OMA, EggNOG |
| Cow | 281536 | TLR4 | toll like receptor 4 | 9913 | VGNC:52834 | Inparanoid, OMA, EggNOG |
| Pig | 399541 | TLR4 | toll like receptor 4 | 9823 | | Inparanoid, OMA |
| Opossum | 100014467 | TLR4 | toll like receptor 4 | 13616 | | Inparanoid, EggNOG |
| Platypus | | TLR4 | toll like receptor 4 [Source:HGNC Symbol;Acc:HGNC:11850] | 9258 | | OMA, EggNOG |
| Chicken | 417241 | TLR4 | toll like receptor 4 | 9031 | CGNC:5282 | Inparanoid, OMA, EggNOG |
| Anole lizard | 100559216 | tlr4 | toll like receptor 4 | 28377 | | Inparanoid, OMA, EggNOG |
| Zebrafish | 403131 | tlr4ba | toll-like receptor 4b, duplicate a | 7955 | ZDB-GENE-040219-8 | OMA, EggNOG |
| Zebrafish | 403132 | tlr4bb | toll-like receptor 4b, duplicate b | 7955 | ZDB-GENE-040219-9 | Inparanoid, OMA |
Associated Recombinant Proteins
| Name | Specification and purity | Expression system | Protein label | Activity | View Details |
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Associated Antibodies
| Name | Specifications | Species reactivity | species | Application | View Details |
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Associated Approved Drugs
Associated Active Ligands
Pathway
| Data Source | Name | Explore more targets | Explore in Source |
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