TPCN1

DescriptionTwo pore calcium channel protein 1

Gene and Protein Information

Gene ID53373
Uniprot Accession IDs A7E258 Q86XS9 Q8NC20
Ensembl ID ENSP00000448083
Symbol KIAA1169 TPC1 TPC1
FamilyBelongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. Two pore calcium channel subfamily.
Sequence
MAVSLDDDVPLILTLDEGGSAPLAPSNGLGQEELPSKNGGSYAIHDSQAPSLSSGGESSPSSPAHNWEMNYQEAAIYLQEGENNDKFFTHPKDAKALAAYLFAHNHLFYLMELATALLLLLLSLCEAPAVPALRLGIYVHATLELFALMVVVFELCMKLRWLGLHTFIRHKRTMVKTSVLVVQFVEAIVVLVRQMSHVRVTRALRCIFLVDCRYCGGVRRNLRQIFQSLPPFMDILLLLLFFMIIFAILGFYLFSPNPSDPYFSTLENSIVSLFVLLTTANFPDVMMPSYSRNPWSCVFFIVYLSIELYFIMNLLLAVVFDTFNDIEKRKFKSLLLHKRTAIQHAYRLLISQRRPAGISYRQFEGLMRFYKPRMSARERYLTFKALNQNNTPLLSLKDFYDIYEVAALKWKAKKNREHWFDELPRTALLIFKGINILVKSKAFQYFMYLVVAVNGVWILVETFMLKGGNFFSKHVPWSYLVFLTIYGVELFLKVAGLGPVEYLSSGWNLFDFSVTVFAFLGLLALALNMEPFYFIVVLRPLQLLRLFKLKERYRNVLDTMFELLPRMASLGLTLLIFYYSFAIVGMEFFCGIVFPNCCNTSTVADAYRWRNHTVGNRTVVEEGYYYLNNFDNILNSFVTLFELTVVNNWYIIMEGVTSQTSHWSRLYFMTFYIVTMVVMTIIVAFILEAFVFRMNYSRKNQDSEVDGGITLEKEISKEELVAVLELYREARGASSDVTRLLETLSQMERYQQHSMVFLGRRSRTKSDLSLKMYQEEIQEWYEEHAREQEQQRQLSSSAAPAAQQPPGSRQRSQTVT
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Homologous gene and protein info.
SpeciesGene IDGene SymbolNameTax IDOther Gene IDSources
Chimp452272TPCN1two pore segment channel 19598VGNC:13480OMA, EggNOG
Macaque712964TPCN1two pore segment channel 19544Inparanoid, OMA, EggNOG
Mouse252972Tpcn1two pore channel 110090MGI:2182472Inparanoid, OMA, EggNOG
Rat246215Tpcn1two pore segment channel 110116RGD:708494Inparanoid, OMA
Dog477492TPCN1two pore segment channel 19615VGNC:47732Inparanoid, OMA
Horse100051154TPCN1two pore segment channel 19796VGNC:24426Inparanoid, OMA
Cow510830TPCN1two pore segment channel 19913VGNC:36243Inparanoid, OMA, EggNOG
Opossum100028547TPCN1two pore segment channel 113616Inparanoid, OMA, EggNOG
Chicken417033TPCN1two pore segment channel 19031CGNC:6333Inparanoid, OMA, EggNOG
Zebrafish567534tpcn1two pore segment channel 17955ZDB-GENE-060526-199Inparanoid, OMA, EggNOG

Protein Classes

DTO Classes
protein    /    Ion channel    /    Calcium channel alpha-1 subunit family    /    Two pore calcium channel subfamily    /    Two pore calcium channel protein 1

Associated Recombinant Proteins

NameSpecification and purityExpression systemProtein labelActivityView Details

Associated Antibodies

NameSpecificationsSpecies reactivityspeciesApplicationView Details

Associated Approved Drugs

    Associated Active Ligands

      Associated Diseases

      NameDisease TypeMondoid

      Pathway

      Data SourceNameExplore more targetsExplore in Source