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TERT

DescriptionTelomerase reverse transcriptase

Gene and Protein Information

Gene ID7015
Uniprot Accession IDs O14783 Q2XS35 Q8N6C3 Q8NG38 Q8NG46
Ensembl ID ENSP00000309572
Symbol EST2 TCS1 TRT TP2 TRT CMM9 EST2 TCS1 hTRT DKCA2 DKCB4 hEST2 PFBMFT1
FamilyBelongs to the reverse transcriptase family. Telomerase subfamily.
Sequence
MPRAPRCRAVRSLLRSHYREVLPLATFVRRLGPQGWRLVQRGDPAAFRALVAQCLVCVPWDARPPPAAPSFRQVSCLKELVARVLQRLCERGAKNVLAFGFALLDGARGGPPEAFTTSVRSYLPNTVTDALRGSGAWGLLLRRVGDDVLVHLLARCALFVLVAPSCAYQVCGPPLYQLGAATQARPPPHASGPRRRLGCERAWNHSVREAGVPLGLPAPGARRRGGSASRSLPLPKRPRRGAAPEPERTPVGQGSWAHPGRTRGPSDRGFCVVSPARPAEEATSLEGALSGTRHSHPSVGRQHHAGPPSTSRPPRPWDTPCPPVYAETKHFLYSSGDKEQLRPSFLLSSLRPSLTGARRLVETIFLGSRPWMPGTPRRLPRLPQRYWQMRPLFLELLGNHAQCPYGVLLKTHCPLRAAVTPAAGVCAREKPQGSVAAPEEEDTDPRRLVQLLRQHSSPWQVYGFVRACLRRLVPPGLWGSRHNERRFLRNTKKFISLGKHAKLSLQELTWKMSVRDCAWLRRSPGVGCVPAAEHRLREEILAKFLHWLMSVYVVELLRSFFYVTETTFQKNRLFFYRKSVWSKLQSIGIRQHLKRVQLRELSEAEVRQHREARPALLTSRLRFIPKPDGLRPIVNMDYVVGARTFRREKRAERLTSRVKALFSVLNYERARRPGLLGASVLGLDDIHRAWRTFVLRVRAQDPPPELYFVKVDVTGAYDTIPQDRLTEVIASIIKPQNTYCVRRYAVVQKAAHGHVRKAFKSHVSTLTDLQPYMRQFVAHLQETSPLRDAVVIEQSSSLNEASSGLFDVFLRFMCHHAVRIRGKSYVQCQGIPQGSILSTLLCSLCYGDMENKLFAGIRRDGLLLRLVDDFLLVTPHLTHAKTFLRTLVRGVPEYGCVVNLRKTVVNFPVEDEALGGTAFVQMPAHGLFPWCGLLLDTRTLEVQSDYSSYARTSIRASLTFNRGFKAGRNMRRKLFGVLRLKCHSLFLDLQVNSLQTVCTNIYKILLLQAYRFHACVLQLPFHQQVWKNPTFFLRVISDTASLCYSILKAKNAGMSLGAKGAAGPLPSEAVQWLCHQAFLLKLTRHRVTYVPLLGSLRTAQTQLSRKLPGTTLTALEAAANPALPSDFKTILD
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Homologous gene and protein info.
SpeciesGene IDGene SymbolNameTax IDOther Gene IDSources
Chimp101058547TERTtelomerase reverse transcriptase9598VGNC:4192Inparanoid, OMA, EggNOG
Macaque709865TERTtelomerase reverse transcriptase9544Inparanoid, OMA, EggNOG
Mouse21752Terttelomerase reverse transcriptase10090MGI:1202709Inparanoid, OMA, EggNOG
Rat301965Terttelomerase reverse transcriptase10116RGD:70494Inparanoid, OMA, EggNOG
Dog403412TERTtelomerase reverse transcriptase9615VGNC:47255Inparanoid, OMA, EggNOG
Cow518884TERTtelomerase reverse transcriptase9913VGNC:35751Inparanoid, OMA, EggNOG
Pig492280TERTtelomerase reverse transcriptase9823Inparanoid, OMA, EggNOG
Opossum103104146TERTtelomerase reverse transcriptase13616Inparanoid, OMA, EggNOG
PlatypusTERTtelomerase reverse transcriptase [Source:HGNC Symbol;Acc:HGNC:11730]9258OMA, EggNOG
Chicken420972TERTtelomerase reverse transcriptase9031CGNC:9953Inparanoid, OMA, EggNOG
Anole lizard103278585terttelomerase reverse transcriptase28377Inparanoid, OMA, EggNOG
Xenopusterttelomerase reverse transcriptase [Source:Xenbase;Acc:XB-GENE-6451333]8364OMA, EggNOG
Zebrafish796551terttelomerase reverse transcriptase7955ZDB-GENE-080405-1Inparanoid, OMA, EggNOG
S.cerevisiae851028EST2Est2p4932S000004310Inparanoid, EggNOG

Protein Classes

PANTHER Classes
protein    /    nucleic acid binding    /    reverse transcriptase    /    Telomerase reverse transcriptase
DTO Classes
protein    /    Enzyme    /    Transferase    /    Nucleotidyltransferase    /    Polymerase    /    Reverse transcriptase    /    Telomerase reverse transcriptase

Associated Recombinant Proteins

NameSpecification and purityExpression systemProtein labelActivityView Details

Associated Antibodies

NameSpecificationsSpecies reactivityspeciesApplicationView Details

Associated Approved Drugs

    Associated Active Ligands

      Associated Diseases

      NameDisease TypeMondoid

      Pathway

      Data SourceNameExplore more targetsExplore in Source
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