TMPRSS6

DescriptionTransmembrane protease serine 6

Gene and Protein Information

Gene ID164656
Uniprot Accession IDs B0QYB4 B0QYB7 B0QYB8 Q5TI06 Q6ICC2 Q6UXD8 Q8IUE2 Q8IXV8
Ensembl ID ENSP00000371211
Symbol IRIDA
FamilyBelongs to the peptidase S1 family.
Sequence
MLLLFHSKRMPVAEAPQVAGGQGDGGDGEEAEPEGMFKACEDSKRKARGYLRLVPLFVLLALLVLASAGVLLWYFLGYKAEVMVSQVYSGSLRVLNRHFSQDLTRRESSAFRSETAKAQKMLKELITSTRLGTYYNSSSVYSFGEGPLTCFFWFILQIPEHRRLMLSPEVVQALLVEELLSTVNSSAAVPYRAEYEVDPEGLVILEASVKDIAALNSTLGCYRYSYVGQGQVLRLKGPDHLASSCLWHLQGPKDLMLKLRLEWTLAECRDRLAMYDVAGPLEKRLITSVYGCSRQEPVVEVLASGAIMAVVWKKGLHSYYDPFVLSVQPVVFQACEVNLTLDNRLDSQGVLSTPYFPSYYSPQTHCSWHLTVPSLDYGLALWFDAYALRRQKYDLPCTQGQWTIQNRRLCGLRILQPYAERIPVVATAGITINFTSQISLTGPGVRVHYGLYNQSDPCPGEFLCSVNGLCVPACDGVKDCPNGLDERNCVCRATFQCKEDSTCISLPKVCDGQPDCLNGSDEEQCQEGVPCGTFTFQCEDRSCVKKPNPQCDGRPDCRDGSDEEHCDCGLQGPSSRIVGGAVSSEGEWPWQASLQVRGRHICGGALIADRWVITAAHCFQEDSMASTVLWTVFLGKVWQNSRWPGEVSFKVSRLLLHPYHEEDSHDYDVALLQLDHPVVRSAAVRPVCLPARSHFFEPGLHCWITGWGALREGGPISNALQKVDVQLIPQDLCSEVYRYQVTPRMLCAGYRKGKKDACQGDSGGPLVCKALSGRWFLAGLVSWGLGCGRPNYFGVYTRITGVISWIQQVVT
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Homologous gene and protein info.
SpeciesGene IDGene SymbolNameTax IDOther Gene IDSources
Chimp458805TMPRSS6transmembrane serine protease 69598VGNC:53409OMA, EggNOG
Macaque696094TMPRSS6transmembrane protease, serine 69544Inparanoid, OMA, EggNOG
Mouse71753Tmprss6transmembrane serine protease 610090MGI:1919003Inparanoid, OMA, EggNOG
Rat315388Tmprss6transmembrane serine protease 610116RGD:1307138Inparanoid, OMA, EggNOG
Dog608593TMPRSS6transmembrane serine protease 69615VGNC:47636Inparanoid, OMA, EggNOG
Horse100069647TMPRSS6transmembrane serine protease 69796VGNC:24345Inparanoid, OMA, EggNOG
Cow614844TMPRSS6transmembrane serine protease 69913VGNC:36144Inparanoid, OMA, EggNOG
Pig100516673TMPRSS6transmembrane protease, serine 69823OMA, EggNOG
Opossum100025330TMPRSS6transmembrane protease, serine 613616Inparanoid, OMA, EggNOG
PlatypusTMPRSS6transmembrane serine protease 6 [Source:HGNC Symbol;Acc:HGNC:16517]9258OMA, EggNOG
Chicken418046TMPRSS6transmembrane protease, serine 69031CGNC:9483Inparanoid, OMA, EggNOG
Anole lizardTMPRSS6transmembrane serine protease 6 [Source:HGNC Symbol;Acc:HGNC:16517]28377Inparanoid, OMA, EggNOG
Xenopustmprss6transmembrane serine protease 6 [Source:Xenbase;Acc:XB-GENE-1011573]8364OMA, EggNOG

Protein Classes

PANTHER Classes
protein    /    serine protease    /    Transmembrane protease serine 6
DTO Classes
protein    /    Enzyme    /    Protease    /    Serine protease    /    Transmembrane protease serine 6

Associated Recombinant Proteins

NameSpecification and purityExpression systemProtein labelActivityView Details

Associated Antibodies

NameSpecificationsSpecies reactivityspeciesApplicationView Details

Associated Approved Drugs

    Associated Active Ligands

      Associated Diseases

      NameDisease TypeMondoid

      Pathway

      Data SourceNameExplore more targetsExplore in Source