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ERBB3
| Description | Receptor tyrosine-protein kinase erbB-3 |
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Gene and Protein Information
| Gene ID | 2065 |
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| Uniprot Accession IDs | A8K6L6 B4DIK7 B4DV32 E9PDT8 Q9BUD7 |
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| Ensembl ID | ENSP00000267101 |
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| Symbol | HER3 HER3 FERLK LCCS2 ErbB-3 c-erbB3 erbB3-S MDA-BF-1 c-erbB-3 p180-ErbB3 p45-sErbB3 p85-sErbB3 |
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| Family | Belongs to the protein kinase superfamily. Tyr protein kinase family. EGF receptor subfamily. |
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| Sequence | MRANDALQVLGLLFSLARGSEVGNSQAVCPGTLNGLSVTGDAENQYQTLYKLYERCEVVMGNLEIVLTGHNADLSFLQWIREVTGYVLVAMNEFSTLPLPNLRVVRGTQVYDGKFAIFVMLNYNTNSSHALRQLRLTQLTEILSGGVYIEKNDKLCHMDTIDWRDIVRDRDAEIVVKDNGRSCPPCHEVCKGRCWGPGSEDCQTLTKTICAPQCNGHCFGPNPNQCCHDECAGGCSGPQDTDCFACRHFNDSGACVPRCPQPLVYNKLTFQLEPNPHTKYQYGGVCVASCPHNFVVDQTSCVRACPPDKMEVDKNGLKMCEPCGGLCPKACEGTGSGSRFQTVDSSNIDGFVNCTKILGNLDFLITGLNGDPWHKIPALDPEKLNVFRTVREITGYLNIQSWPPHMHNFSVFSNLTTIGGRSLYNRGFSLLIMKNLNVTSLGFRSLKEISAGRIYISANRQLCYHHSLNWTKVLRGPTEERLDIKHNRPRRDCVAEGKVCDPLCSSGGCWGPGPGQCLSCRNYSRGGVCVTHCNFLNGEPREFAHEAECFSCHPECQPMEGTATCNGSGSDTCAQCAHFRDGPHCVSSCPHGVLGAKGPIYKYPDVQNECRPCHENCTQGCKGPELQDCLGQTLVLIGKTHLTMALTVIAGLVVIFMMLGGTFLYWRGRRIQNKRAMRRYLERGESIEPLDPSEKANKVLARIFKETELRKLKVLGSGVFGTVHKGVWIPEGESIKIPVCIKVIEDKSGRQSFQAVTDHMLAIGSLDHAHIVRLLGLCPGSSLQLVTQYLPLGSLLDHVRQHRGALGPQLLLNWGVQIAKGMYYLEEHGMVHRNLAARNVLLKSPSQVQVADFGVADLLPPDDKQLLYSEAKTPIKWMALESIHFGKYTHQSDVWSYGVTVWELMTFGAEPYAGLRLAEVPDLLEKGERLAQPQICTIDVYMVMVKCWMIDENIRPTFKELANEFTRMARDPPRYLVIKRESGPGIAPGPEPHGLTNKKLEEVELEPELDLDLDLEAEEDNLATTTLGSALSLPVGTLNRPRGSQSLLSPSSGYMPMNQGNLGESCQESAVSGSSERCPRPVSLHPMPRGCLASESSEGHVTGSEAELQEKVSMCRSRSRSRSPRPRGDSAYHSQRHSLLTPVTPLSPPGLEEEDVNGYVMPDTHLKGTPSSREGTLSSVGLSSVLGTEEEDEDEEYEYMNRRRRHSPPHPPRPSSLEELGYEYMDVGSDLSASLGSTQSCPLHPVPIMPTAGTTPDEDYEYMNRQRDGGGPGGDYAAMGACPASEQGYEEMRAFQGPGHQAPHVHYARLKTLRSLEATDSAFDNPDYWHSRLFPKANAQRT Show more |
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Homologous gene and protein info.
| Species | Gene ID | Gene Symbol | Name | Tax ID | Other Gene ID | Sources |
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| Macaque | | RPS26 | erb-b2 receptor tyrosine kinase 3 [Source:HGNC Symbol;Acc:HGNC:3431] | 9544 | | OMA, EggNOG |
| Mouse | 13867 | Erbb3 | erb-b2 receptor tyrosine kinase 3 | 10090 | MGI:95411 | Inparanoid, OMA, EggNOG |
| Rat | 29496 | Erbb3 | erb-b2 receptor tyrosine kinase 3 | 10116 | RGD:69323 | Inparanoid, OMA, EggNOG |
| Dog | 481105 | ERBB3 | erb-b2 receptor tyrosine kinase 3 | 9615 | VGNC:54147 | Inparanoid, OMA, EggNOG |
| Horse | 100059216 | ERBB3 | erb-b2 receptor tyrosine kinase 3 | 9796 | VGNC:17650 | Inparanoid, OMA, EggNOG |
| Cow | 785655 | ERBB3 | erb-b2 receptor tyrosine kinase 3 | 9913 | VGNC:28564 | Inparanoid, OMA, EggNOG |
| Opossum | | ERBB3 | erb-b2 receptor tyrosine kinase 3 [Source:HGNC Symbol;Acc:HGNC:3431] | 13616 | | Inparanoid, OMA, EggNOG |
| Anole lizard | 100556326 | erbb3 | erb-b2 receptor tyrosine kinase 3 | 28377 | | Inparanoid, OMA |
| Xenopus | 100493384 | erbb3 | erb-b2 receptor tyrosine kinase 3 | 8364 | XB-GENE-853369 | Inparanoid, OMA, EggNOG |
| Zebrafish | 544664 | erbb3b | erb-b2 receptor tyrosine kinase 3b | 7955 | ZDB-GENE-050107-1 | Inparanoid, OMA |
| C. elegans | 174462 | let-23 | Receptor protein-tyrosine kinase | 6239 | | OMA, EggNOG |
Associated Recombinant Proteins
| Name | Specification and purity | Expression system | Protein label | Activity | View Details |
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Associated Antibodies
| Name | Specifications | Species reactivity | species | Application | View Details |
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Associated Approved Drugs
Associated Active Ligands
Pathway
| Data Source | Name | Explore more targets | Explore in Source |
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