Protein or Target Summary
General transcription and DNA repair factor IIH helicase subunit XPB
| Gene ID | 2071 |
|---|---|
| uniprot | P19447 |
| Gene Name | ERCC3 |
| Ensernbl ID | ENSP00000285398 |
| Family | Belongs to the helicase family. RAD25/XPB subfamily. |
| Sequence | MGKRDRADRDKKKSRKRHYEDEEDDEEDAPGNDPQEAVPSAAGKQVDESGTKVDEYGAKDYRLQMPLKDDHTSRPLWVAPDGHIFLEAFSPVYKYAQDFLVAIAEPVCRPTHVHEYKLTAYSLYAAVSVGLQTSDITEYLRKLSKTGVPDGIMQFIKLCTVSYGKVKLVLKHNRYFVESCHPDVIQHLLQDPVIRECRLRNSEGEATELITETFTSKSAISKTAESSGGPSTSRVTDPQGKSDIPMDLFDFYEQMDKDEEEEEETQTVSFEVKQEMIEELQKRCIHLEYPLLAEYDFRNDSVNPDINIDLKPTAVLRPYQEKSLRKMFGNGRARSGVIVLPCGAGKSLVGVTAACTVRKRCLVLGNSAVSVEQWKAQFKMWSTIDDSQICRFTSDAKDKPIGCSVAISTYSMLGHTTKRSWEAERVMEWLKTQEWGLMILDEVHTIPAKMFRRVLTIVQAHCKLGLTATLVREDDKIVDLNFLIGPKLYEANWMELQNNGYIAKVQCAEVWCPMSPEFYREYVAIKTKKRILLYTMNPNKFRACQFLIKFHERRNDKIIVFADNVFALKEYAIRLNKPYIYGPTSQGERMQILQNFKHNPKINTIFISKVGDTSFDLPEANVLIQISSHGGSRRQEAQRLGRVLRAKKGMVAEEYNAFFYSLVSQDTQEMAYSTKRQRFLVDQGYSFKVITKLAGMEEEDLAFSTKEEQQQLLQKVLAATDLDAEEEVVAGEFGSRSSQASRRFGTMSSMSGADDTVYMEYHSSRSKAPSKHVHPLFKRFRK Show more |
Gene and Protein Information
| Species | Gene ID | Gene Symbol | Gene Name | Uniprot |
|---|---|---|---|---|
| HUMAN | 2071 | ERCC3 | General transcription and DNA repair factor IIH helicase subunit XPB | P19447 |
| MOUSE | 13872 | Ercc3 | General transcription and DNA repair factor IIH helicase subunit XPB | P49135 |
| MOUSE | Ercc3 | Uncharacterized protein | Q3U3I5 | |
| MOUSE | Ercc3 | Uncharacterized protein | Q3TVD8 | |
| MOUSE | Ercc3 | Ercc3 protein | Q8R1K9 | |
| RAT | 291703 | Ercc3 | General transcription and DNA repair factor IIH helicase subunit XPB | Q4G005 |
Protein Classes
PANTHER Classes
protein / nucleic acid binding / DNA binding protein / TFIIH basal transcription factor complex helicase XPB subunit
protein / nucleic acid binding / DNA helicase / TFIIH basal transcription factor complex helicase XPB subunit
protein / nucleic acid binding / helicase / TFIIH basal transcription factor complex helicase XPB subunit
protein / nucleic acid binding / hydrolase / TFIIH basal transcription factor complex helicase XPB subunit
protein / nucleic acid binding / DNA binding protein / TFIIH basal transcription factor complex helicase XPB subunit
protein / nucleic acid binding / DNA helicase / TFIIH basal transcription factor complex helicase XPB subunit
protein / nucleic acid binding / helicase / TFIIH basal transcription factor complex helicase XPB subunit
protein / nucleic acid binding / hydrolase / TFIIH basal transcription factor complex helicase XPB subunit
DTO Classes
protein / Enzyme / Helicase / DNA helicase / TFIIH basal transcription factor complex helicase XPB subunit
protein / Enzyme / Helicase / DNA helicase / TFIIH basal transcription factor complex helicase XPB subunit
Associated Recombinant Proteins
| Name | Specification and purity | Expression system | Protein label | Activity | View Details |
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Associated Antibodies
| Name | Specifications | Species reactivity | species | Application | View Details |
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Associated Approved Drugs
Associated Active Ligands
Associated Diseases
| Name | Disease Type | Mondoid |
|---|
Pathway
| Data Source | Name | Explore more targets | Explore in Source |
|---|
Source: DataSourcesLicenses.xlsx